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Anti-inflammatory and antinociceptive effects of phonophoresis in animal models: a randomized experimental study BJMBR
Cardoso,L.C.P.; Pinto,N.B.; Nobre,M.E.P.; Silva,M.R.; Pires,G.M.; Lopes,M.J.P.; Viana,G.S.B.; Rodrigues,L.M.R..
The aim of this study was to evaluate the therapeutic effects of ultrasound (US)-mediated phonophoresis alone or in association with diclofenac diethylammonium (DCF) administered topically in animal models of inflammation. A pre-clinical, prospective, and randomized experimental study of quantitative and qualitative nature was carried out. Phonophoresis was performed using a therapeutic ultrasound apparatus in two distinct models of acute inflammation. Edema was induced by an intraplantar injection of carrageenan and measured by plethysmography. The Hargreaves test was used to evaluate the antinociceptive activity and investigate the action of phonophoresis on tumor necrosis factor (TNF)-α production. A histological analysis with hematoxylin-eosin was used...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Phonophoresis; Ultrasonic therapy; Inflammation; Nociception; Physiotherapy.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000200603
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