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Evaluation of the predisposition and clinical impact of BK virus replication in kidney transplant patients Anais da ABC (AABC)
MOURA,ELVIANI B.; PETZHOLD,SILVIA V.; AMARAL,AUGUSTO R.; DEBONI,LUCIANE M.; FRANÇA,PAULO H.C. DE.
ABSTRACT The BK virus (BKV) produces a subclinical kidney infection in immunocompetent individuals. However, viremia may occur in kidney transplant patients with ongoing immunosuppression. BKV-associated nephropathy (BKVN) has no specific treatment and is a leading cause of organ transplant loss. In this study, we evaluated the predisposition and the clinical impact of BKV replication in kidney transplant patients during post-transplant monitoring in a reference institution in Brazil. Demographic, clinical and laboratory data generated during routine outpatient follow-up were retrospectively collected. BK viremia was investigated using real-time polymerase chain reaction. Of the 553 participants, 7.4% (n = 41) presented BKV replication. Of these, 16 (39%)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: BK virus; Nephropathy; Renal transplantation; Viremia.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000200675
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