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| PAZIN,WALLANCE M.; SANTOS,SUIKINAI N. DOS; QUEIROZ,SONIA C.N.; BAGATOLLI,LUIS A.; SOARES,ADEMILSON E.E.; MELO,ITAMAR S. DE; ITO,AMANDO S.. |
| Abstract: We have established how natural compounds from green propolis collected by the species Apis mellifera act against the growth of Pythium aphanidermatum. On the basis of mass spectrometry (Q-ToF MS), we determined that Artepillin C, the major constituent of green propolis, underlies the effect and displays activity against P. aphanidermatum at a minimal inhibitory concentration of 750 µg.mL-1. Biophysical studies based on model membranes showed that this inhibitory effect may be linked with a membrane-related phenomenon: Artepillin C increases the permeability of membranes with relatively high fluidity in their lateral structure, a feature that is in line with the lipid composition reported for the cytoplasmic membrane of P. aphanidermatum.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Green propolis; Artepillin C; Fungicide; Pythium aphanidermatum; Model membranes. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300617 |
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