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	Provedor de dados 56 (1) Autor Wang,D. (1) Wang,H. (1) Wu,G. (1) Xuan,J.W. (1) Yuan,J. (1) Palavra-chave Gleason grading system (1) KIMAP mouse model (1) Prostate adenocarcinoma (1) Prostate cancer model (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2006 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Histopathological characteristics of a novel knock-in mouse prostate cancer model 56 Wu,G.; Wang,D.; Wang,H.; Yuan,J.; Xuan,J.W.. Prostate cancer is relatively unique to man. There is no naturally occurring prostate cancer in the mouse. Pre-clinical studies involve the establishment of a genetically engineered mouse prostate cancer model with features close to those of the human situation. A new knock-in mouse adenocarcinoma prostate (KIMAP) model was established, which showed close-to-human kinetics of tumor development. In order to determine if the similar kinetics is associated with heterogeneous tumor architecture similar to the human situation, we utilized a new mouse histological grading system (Gleason analogous grading system) similar to the Gleason human grading system and flow cytometry DNA analysis to measure and compare the adenocarcinoma of the KIMAP model with human... Tipo: Info:eu-repo/semantics/article Palavras-chave: Prostate cancer model; KIMAP mouse model; Gleason grading system; Prostate adenocarcinoma. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600008 Registros recuperados: 1 Primeira ... 1 ... Última

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