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Primary open-angle glaucoma: association with cholesterol 24S-hydroxylase (CYP46A1) gene polymorphism and plasma 24-hydroxycholesterol levels Inra
Fourgeux, C.; Lucy, M.; Björkhem, I.; Diczfalusy, U.; Joffre, C.; Acar, N.; Creuzot Garcher, C.; Bron, A.; Bretillon, L..
Purpose. Genetics has made significant contributions to the study of glaucoma over the past few decades. Cholesterol-24S-hydroxylase (CYP46A1) is a cholesterol-metabolizing enzyme that is especially expressed in retinal ganglion cells. CYP46A1 and its metabolic product, 24S-hydroxycholesterol, have been linked to neurodegeneration. A single-nucleotide polymorphism (SNP) in the CYP46A1 gene, designated as rs754203 and associated with Alzheimer disease, was evaluated as a genetic risk factor for primary open-angle glaucoma (POAG), as well as plasma 24S-hydroxycholesterol levels. Methods. The frequency of the CYP46*C and CYP46*T alleles was analyzed in 150 patients with POAG and 118 control subjects. Plasma 24S-hydroxycholesterol levels were quantified. Sex,...
Tipo: Journal Article Palavras-chave: NORMAL-TENSION GLAUCOMA; ALZHEIMERS-DISEASE; ; PRESSURE; RISK-FACTORS.
Ano: 2009 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2010b05f88bb&uri=/notices/prodinra1/2010/07/
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Re-evaluation of the liming-fertilization interaction in grasslands on poor and acid soils Inra
Poozesh, V.; Castillon, P.; Cruz, P.; BERTONI, G..
The effect of surface liming on herbage production in permanent grasslands is rather uncertain. To better understand the effect of liming on the grassland, a study was made with a field experiment and a pot experiment with soil from the same field. In the field, the effects of liming and NPK fertilization on the production and composition of the vegetation were studied. In pots, the effects of liming and phosphate fertilization on different grass species were analysed. The effect of NPK fertilization (+3Æ96 t ha)1) on the production of the original grassland was greater than that of liming (+0Æ68 t ha)1),which was only observed (P < 0Æ05) on the unfertilized plots. Liming increased the total number of species and the proportion of dicotyledons. After...
Tipo: Journal Article Palavras-chave: SOIL ACIDITY; ROOT GROWTH; PHOSPHORUS; ALUMINIUM; ;  .
Ano: 2010 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2010a6593dcd&uri=/notices/prodinra1/2010/06/
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Sensibilité aux Pythium et mauvaise germination en sol froid chez le haricot (Phaseolus vulgaris L) Inra
Ginoux, J.P.; Messiaen, C.M..
Les manques à la levée observés sur haricot en semis précoce au printemps sont principalement dus aux attaques de Pythium. D’importantes différences de sensibilité peuvent être mises en évidence entre variétés par des méthodes de contamination les mettant en présence de souches de Pythium douées de divers niveaux d’agressivité. Les variétés à grain coloré sont, de façon générale, moins sensibles que celles à tégument incolore, et parmi celles-ci les flageolets verts sont les plus sensibles. L’étude de la descendance d’un croisement (noir résistant x flageolet vert) met en évidence l’effet sensibilisant de 2 gènes récessifs, l’un conditionnant l’absence de coloration, l’autre le caractère «flageolet». Cependant, il y a aussi des différences de sensibilité...
Tipo: Journal Article Palavras-chave: SOL FROID; PYTHIUM; ;  .
Ano: 1993 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2009ba6c1a9b&uri=/notices/prodinra1/2009/10/
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Social and semantic coevolution in knowledge networks Inra
Roth, C.; Cointet, J.P..
Socio-semantic networks involve agents creating and processing information: communities of scientists, software developers, wild Contributors and webloggers are, among others, examples Of Such knowledge networks. We aim at demonstrating that the dynamics of these communi ties can be adequately described as the coevolution of a social and a socio-semantic network. More precisely, we will first introduce a theoretical framework based on a social network and a socio-semantic network, i.e. an epistemic network featuring agents. concepts and links between agents and between agents and concepts. Adopting a relevant empirical protocol. we will then describe the joint dynamics of social and socio-semantic structures, at both macroscopic and microscopic scales,...
Tipo: Journal Article Palavras-chave: SCIENTIFIC COLLABORATION STATISTICAL EVALUATION; EPISTEMIC COMMUNITIES; GALOIS LATTICES; MODELS; DISTRIBUTIONS; BLOCKMODELS; EVOLUTION; DYNAMICS; KNOWLEDGE NETWORKS; SOCIO-SEMANTIC NETWORKS; HIERARCHIES; DYNAMICS; COHESIVENESS; EPISTEMIC COMMUNITIES; BICLIQUES; ; BLOGS; SCIENTIFIC NETWORKS.
Ano: 2010 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD20117c62aa39&uri=/notices/prodinra1/2011/07/
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Sorghum Variety ICSV 1 Open Agri
 

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