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| Pazin-Filho,A.; de Jesus,A.M.X.; Magalhães,P.K.R.; Melato,L.H.; Campos,D.; Maciel,B.C.; Maciel,L.M.Z.. |
| Amiodarone-induced thyroid dysfunction (AITD) is a common complication of amiodarone therapy and its prevalence varies according to iodine intake, subclinical thyroid disorders and the definition of AITD. There is no consensus about the frequency of screening for this condition. We evaluated 121 patients on chronic regular intake of amiodarone (mean intake = 248.5 ± 89 mg; duration of treatment = 5.3 ± 3.9 years, range = 0.57-17 years) and with stable baseline cardiac condition. Those with no AITD were followed up for a median period of 3.2 years (range: 0.6-6.7) and the incidence rate of AITD, defined by clinical and laboratorial findings as proposed by international guidelines, was obtained (62.8 per 1000 patients/year). We applied the Cox proportional... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amiodarone; Chagas’ disease; Thyroid dysfunction; Antiarrhythmic drug. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000800009 |
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