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| Xavier,Melissa O.; Soares,Mauro P.; Meinerz,Ana Raquel M.; Nobre,Márcia O.; Osório,Luiza G.; Silva Filho,Rodolfo P. da; Meireles,Mário Carlos A.. |
| The article describes the epidemiology, macroscopic and histological lesions as well as the isolation of Aspergillus flavus and A. fumigatus from Magellanic penguins (Spheniscus magellanicus) during recovery in the Center for Recovery of Marine Animals (CRAM - 32ºS/52ºW), over a period of two years. From January 2004 to December 2005 the Center received 52 Magellanic penguins, and 23% (12/52) died. Necropsies were performed and tissue samples were collected for histological and microbiological examination. From 12 dead animals, aspergillosis was confirmed in five animals, corresponding to 42% of the mortality. Granulomatous nodules were observed mainly on air sacs and lungs. Histologically, septate and branching hyphae, measuring 3-5 µm and PAS positive... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aspergillosis; Rehabilitation; Penguins; Captivity. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000300018 |
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| 豊留, 孝仁; TOYOTOME, Takahito. |
| Aspergillus species (spp.) are medically important pathogens that cause aspergillosis, and A. fumigatus is the most prevalent causative agent of the disease. Aspergillus spp. produce various secondary metabolites; however, the role of these metabolites in aspergillosis remains unclear. Gliotoxin is a major secondary metabolite produced by A. fumigatus. Several recent studies have reported that gliotoxin contributes to the virulence of A. fumigatus. Here I review studies related to gliotoxin and its contribution to the infection caused by A. fumigatus. |
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Palavras-chave: Aspergillosis; Aspergillus fumigatus; Gliotoxin; Secondary metabolite. |
| Ano: 2015 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4157 |
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