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| Santos-Machado,T.M.; Cristófani,L.M.; Almeida,M.T.A.; Maluf,P.T.; Costa,P.A.; Pereira,M.A.; Brito,J.L.B.C.; Odone-Filho,V.. |
| Symptomatic involvement of the gastrointestinal (GI) tract as a prominent symptom in Langerhans' cell histiocytosis (LCH) is uncommon, occurring in less than 1 to 5% of all cases, even when the disease is in its disseminated form. Up to now, there have been reports of 18 cases of LCH with GI manifestations, including our 2 cases, with diarrhea (77.7%), protein-losing enteropathy (33.3%) and bloody stool being the most frequent findings. The authors present two patients with severe diarrhea and refractory hypoalbuminemia, and with the protein-losing enteropathy documented by Cr51-labeled albumin studies. A review of the literature indicated that the presence of GI symptoms is often associated with systemic disease as well as with poor prognosis, mainly... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Langerhans' cell histiocytosis; Histiocytosis X; Gastrointestinal involvement; Protein-losing enteropathy; Hypoalbuminemia; Cr51-labeled albumin test. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000900007 |
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