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Ritterbusch,G.A.; Esteves,P.A.; Trevisol,I.M.; Okino,C.H.; Jaenisch,F.R.F.; Morés,M.A.Z.; Caron,L.; Silva,A.D.; Finger,P.F.; Hübner,S.O.. |
RESUMO A vacinação é a forma mais utilizada para prevenir a bronquite infecciosa causada pelo vírus da bronquite infecciosa das galinhas (IBV). Contudo, as vacinas convencionais são incapazes de diferenciar aves infectadas de vacinadas. No presente trabalho foi construído, caracterizado, e avaliado como candidato vacinal, um adenovírus recombinante expressando o gene N do IBV. O gene N foi clonado em um adenovírus humano tipo 5 defectivo e transfectado para as células HEK-293A para gerar rAd5_N. Após o vetor ser obtido como esperado e a confirmação da expressão da proteína N em HEK-293ª, foi realizada inoculação pela via oculo-nasal na dose de 10 7 TCID 50 /0,1mL para imunização de galinhas livres de patógenos específicos (SPF). A resposta imunológica do... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Infectious bronchitis virus; Nucleocapsid protein; Adenovirus vector; Immune responses. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000401428 |
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Roschel,H.; Barroso,R.; Batista,M.; Ugrinowitsch,C.; Tricoli,V.; Arsati,F.; Lima-Arsati,Y.B.; Araújo,V.C.; Moreira,A.. |
A single bout of resistance exercise (RE) induces hormonal and immune responses, playing an important role in a long-term adaptive process. Whole-body vibration (WBV) has also been shown to affect hormonal responses. Evidence suggests that combining WBV with RE may amplify hormonal and immune responses due to the increased neuromuscular load. Therefore, the aim of this study was to evaluate salivary cortisol (Scortisol) and salivary IgA (SIgA) concentrations following a RE session combined or not with WBV. Nine university students (22.9 ± 5.1 years, 175.8 ± 5.2 cm, and 69.2 ± 7.3 kg) performed five sets of squat exercise (70% one-repetition-maximum) combined (R+V30) or not (R) with WBV at 30 Hz. Saliva samples were obtained before and after exercise.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Upper respiratory tract infection; Hormonal responses; Immune responses; Neuromuscular training. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000600013 |
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Sorgi,Sara; Bonezi,Vivian; Dominguez,Mariana R.; Gimenez,Alba Marina; Dobrescu,Irina; Boscardin,Silvia; Nakaya,Helder I.; Bargieri,Daniel Y.; Soares,Irene S.; Silveira,Eduardo L. V.. |
Abstract Two years ago, we held an exciting event entitled the São Paulo School of Advanced Sciences on Vaccines (SPSASV). Sixty-eight Ph.D. students, postdoctoral fellows and independent researchers from 37 different countries met at the Mendes Plaza Hotel located in the city of Santos, SP - Brazil to discuss the challenges and the new frontiers of vaccinology. The SPSASV provided a critical and comprehensive view of vaccine research from basics to the current state-of-the-art techniques performed worldwide. For 10 days, we discussed all the aspects of vaccine development in 36 lectures, 53 oral presentations and 2 poster sessions. At the end of the course, participants were further encouraged to present a model of a grant proposal related to vaccine... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vaccine history; WHO priorities and challenges; Immune responses; Antigen search; Delivery systems and strategies. |
Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100201 |
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Sayehban,P; Seidavi,A; Dadashbeiki,M; Ghorbani,A; Araújo,WAG; Albino,LFT. |
ABSTRACT The effects of the dietary inclusion of olive pulp (OP) and the supplementation of a commercial enzyme blend (ENZ) on the gastrointestinal tract (GIT) size, and immune and hematological parameters were evaluated. In total, 600 one-day-old Ross 308 male broiler chicks were divided into 6 treatments according to a completely randomized design, in a 2×2×2 factorial scheme, consisting of the dietary inclusion of two olive pulp levels (50 and 100 g/kg in diet), two pulp categories (processed and unprocessed), and the inclusion or not of an enzyme blend. On d 42, birds were euthanized and blood samples were collected, and lymphoid, hematologic, and GIT organs were measured. The inclusion of 100g/kg OP in the diets increased jejunum relative weight (J%)... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Alternative feedstuffs; Immune responses; Natural antioxidants; Processing; Visceral physiology.. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2015001000073 |
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