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Munhoz,Lívia Silveira; Vargas,Gilberto D'Ávila; Fischer,Geferson; Lima,Marcelo de; Esteves,Paulo Augusto; Hübner,Silvia de Oliveira. |
Immunoglobulin Y (IgY) is the major antibody isotype in birds, reptiles, amphibia, and lungfish, playing a similar biological role as mammal IgG. Due to its phylogenetic distance, immune diversification and presence in the egg yolk, IgY provide a number of advantages in immunodiagnostic compared to IgG from mammals. Moreover, IgY production is in agreement with international efforts to reduce, refine and if possible, to replace animals in experimentation, contributing substantially in favor of animal welfare. This article presents an overview about structural and functional features, production and applications of IgY in immunodiagnostic, as well as the advantages of chicken antibodies use. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Egg yolk antibody; Immunodiagnostics; Immunoglobulin Y; Polyclonal antibodies. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782014000100025 |
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Paula,Marília Ribeiro De; Rocha,Nathália Brito; Miqueo,Evangelina; Silva,Fernanda Lavínia Moura; Coelho,Marina Gavanski; Bittar,Carla Maris Machado. |
ABSTRACT The objective of this study was to evaluate passive immunity transfer, health, performance, and metabolism of Holstein calves fed colostrum supplement associated with medium-quality colostrum. After birth, calves were blocked according to birth weight and date and distributed into the following treatments: high-quality colostrum (> 50 mg of Ig/mL; n = 15; 150 g kg−1 BW; positive control group); medium-quality colostrum (30-40 mg of Ig/mL; n = 14; 150 g kg−1 BW), and medium-quality colostrum (30-40 mg of Ig/mL; n = 15; 150 g kg−1 BW) + colostrum supplement (15 mL) given with the colostrum. Colostrum was given within the first 12 h of life in two meals by nipple bottle, and colostrum replacer was administered by a blister syringe. Blood samples... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Blood parameters; Colostrum supply; Immunity; Immunoglobulin Y; Intake. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982019000100717 |
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SILVA, M. C. da; SCHAEFER, R.; GAVA, D.; SOUZA, C. K.; VENANCIO, E. J.. |
Introduction and objectives: Influenza is a disease caused by infection of the host respiratory tract by influenza type A virus that affects a wide variety of species, including human, swine, equine, poultry and sea mammals. The viral RNA is encapsidated by the nucleoprotein (NP), which is a highly conserved protein among influenza A viruses. Detection of influenza virus can be accomplished by assessing specific immune response to the virus, by direct detection of viral RNA or virus antigen in infected tissues. Some diagnostic tests use antibodies produced in mammals to influenza virus detection. However, due to high cost and concerns related to animal welfare, alternative production of antibodies in mammals has been described. The immunoglobulin Y (IgY)... |
Tipo: Separatas |
Palavras-chave: Imunocitoquímica; IgY.; Sanidade animal; Virologia; Imunologia.; Immunoglobulin Y; Influenza.. |
Ano: 2017 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1078687 |
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