Consulta: subjectFacets:"Membrane fusion"
Registros recuperados: 1
Data/hora: 27/07/2024 02:56:41

Viral membrane fusion: is glycoprotein G of rhabdoviruses a representative of a new class of viral fusion proteins?
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Da Poian,A.T.; Carneiro,F.A.; Stauffer,F.
Enveloped viruses always gain entry into the cytoplasm by fusion of their lipid envelope with a cell membrane. Some enveloped viruses fuse directly with the host cell plasma membrane after virus binding to the cell receptor. Other enveloped viruses enter the cells by the endocytic pathway, and fusion depends on the acidification of the endosomal compartment. In both cases, virus-induced membrane fusion is triggered by conformational changes in viral envelope glycoproteins. Two different classes of viral fusion proteins have been described on the basis of their molecular architecture. Several structural data permitted the elucidation of the mechanisms of membrane fusion mediated by class I and class II fusion proteins. In this article, we review a number of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Membrane fusion; Fusion proteins; Rhabdovirus; G protein; Glycoprotein.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000600002