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Evaluation of the genotoxicity of zinc oxide-eugenol cement to Allium cepa L. - doi: 10.4025/actascibiolsci.v35i4.17925 Biological Sciences
Rezende, Elisângela de Fátima; Centro Universitário de Lavras; Mendes-Costa, Maria Cristina; Centro Universitário de Lavras; Fonseca, Johnson Campideli; Centro Universitário de Lavras; Ribeiro, Alex Oliveira; Centro Universitário de Lavras.
Evaluation of the Genotoxicity of Zinc Oxide-Eugenol Cement in Allium cepa L. Dental materials can induce local and systemic effects. The Allium cepa assay was used to evaluate the genotoxicity and/or cytotoxicity of zinc oxide and eugenol (ZOE) at different proportions. The ZOE solution was tested at the concentration of 1 drop of eugenol (in each drop of liquid, the approximate concentration of eugenol is 85%) and 1 portion of zinc oxide cement (treatment I), and twice the concentration of eugenol (treatment II). Treated roots appeared to be yellowish-brown, fewer in number, thicker and less turgid compared with the control, suggesting a cytotoxic activity of ZOE. A significant difference was found in the root size between the control and treatment II....
Tipo: Info:eu-repo/semantics/article Palavras-chave: 2.00.00.00-6; 2.02.00.00-5; 2.02.06.00-3 cytotoxicity; Micronucleus (MN); Dental materials; Mutagenesis Genética.
Ano: 2013 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/17925
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Nuclear anomalies in the buccal cells of calcite factory workers Genet. Mol. Biol.
Diler,Songül Budak; Ergene,Serap.
The micronucleus (MN) assay on exfoliated buccal cells is a useful and minimally invasive method for monitoring genetic damage in humans. To determine the genotoxic effects of calcite dust that forms during processing, MN assay was carried out in exfoliated buccal cells of 50 (25 smokers and 25 non-smokers) calcite factory workers and 50 (25 smokers and 25 non-smokers) age- and sex-matched control subjects. Frequencies of nuclear abnormalities (NA) other than micronuclei, such as binucleates, karyorrhexis, karyolysis and 'broken eggs', were also evaluated. Micronuclei and the other aforementioned anomalies were analysed by two way analysis of covariance. The linear correlations between the types of micronucleus and nuclear abnormalities were determined by...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Calcite; Exfoliated buccal cells; Micronucleus (MN); Genotoxicity.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000200028
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