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A factorial design applied to the study of chromium toxicity on the glutathione levels of Brachiaria brizantha and Brachiaria ruziziensis seedlings. Repositório Alice
MARQUES, R.; OLIVEIRA, M. A. L. de; REIS, C. R. G. dos; KOPP, M. M.; PASSOS, L. P..
2015
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Brachiaria ruziziensis; Brachiaria brizantha; Glutathione; Chromium-toxicity; Oxidative stress.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1035418
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A single dose of purple grape juice improves physical performance and antioxidant activity in runners: a randomized, crossover, double‑blind, placebo study. Repositório Alice
TOSCANO, L. de L. T.; SILVA, A. S.; FRANÇA, A. C. L. de; SOUSA, B. R. V. de; ALMEIDA FILHO, E. J. B. de; COSTA, M. da S.; BIASOTO, A. C. T.; SILVA, D. F. da; SENA, K. de F.; CERQUEIRA, G. S.; GONÇALVES, M. da C. R..
PurposeTo investigate the effects of a single dose of juice on physical performance, oxidative stress, inflammation and muscle damage in runners.Methods Fourteen recreational male runners (39 ± 9 years, VO2peak = 55.9 ± 6.5 ml/kg/min) performed two running tests to exhaustion at 80% of VO2max after ingesting grape juice or a placebo drink (10 ml/kg/day) randomly. Blood samples were taken before and 2 h after supplementation and immediately after running to analyze total antioxidant capacity (TAC), malondialdehyde (MDA), alpha-1 acid glycoprotein (A1GPA), high-sensitivity C-reactive protein (hs-CRP), creatine kinase (CK) and lactate dehydrogenase (LDH).ResultsThe participants ran for an average of 59.2 ± 27.8 min until exhaustion in the placebo group and...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Sumo de uva roxa; Desempenho físico; Atividade antioxidante; Nutrição; Uva; Dieta; Polyphenols; Oxidative stress; Athletic performance.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1120803
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Active and passive biomonitoring suggest metabolic adaptation in blue mussels (Mytilus spp.) chronically exposed to a moderate contamination in Brest harbor (France) ArchiMer
Lacroix, Camille; Richard, Gaelle; Seguineau, Catherine; Guyomarch, Julien; Moraga, Dario; Auffret, Michel.
Brest harbor (Bay of Brest, Brittany, France) has a severe past of anthropogenic chemical contamination, but inputs tended to decrease, indicating a reassessment of its ecotoxicological status should be carried out. Here, native and caged mussels (Mytilus spp.) were used in combination to evaluate biological effects of chronic chemical contamination in Brest harbor. Polycyclic aromatic hydrocarbon (PAH) contamination was measured in mussel tissues as a proxy of harbor and urban pollution. Biochemical biomarkers of xenobiotic biotransformation, antioxidant defenses, generation of reducing equivalents, energy metabolism and oxidative damage were studied in both gills and digestive glands of native and caged mussels. In particular, activities of...
Tipo: Text Palavras-chave: Marine biomonitoring; Chronic pollution; Blue mussel Mytilus spp.; Caging; Oxidative stress; Energetic metabolism; Bay of Brest.
Ano: 2015 URL: http://archimer.ifremer.fr/doc/00255/36654/35795.pdf
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Activity of alternative oxidase and plant uncoupling mitochondrial protein in potato tubers stored at low temperature or submitted to artificial aging Braz. J. Plant Physiol.
Pinheiro,Hugo Alves; Borges,Regis; Silva,Marco Aurélio Pedron e; Centeno,Danilo Cruz.
Potato tubers (Solanum tuberosum L. cv. Binje) were stored at 18 and 4ºC in order to verify changes in mitochondrial metabolism, especially in the activities of the alternative oxidase (AOX) and plant uncoupling mitochondria protein (PUMP). Tubers were also sliced and submitted to artificial aging. The oxygen consumption rate (OCR), respiratory control (RC) and ADP/O ratio for mitochondria obtained after storage at 18ºC were not altered, regardless of the time of storage. Considerable increment in OCR, for both respiratory states 3 and 4, was observed after storing the tubers for five and ten days at 4ºC; and it was accomplished by reductions in RC and ADP/O. The AOX activity was evident after five days at 4ºC, and it was enhanced after ten days of storage...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Solanum tuberosum L.; Mitochondrial swelling; Oxidative stress; Respiration.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202004000200001
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Acute toxicity of commercial atrazine in Piaractus mesopotamicus: histopathological, ultrastructural, molecular, and genotoxic evaluation. Repositório Alice
PAIVA, P. P. de; DELCORSO, M. C.; MATHEUS, V. A.; QUEIROZ, S. C. do N. de; COLLARES-BUZATO, C. B.; ARANA, S..
The aim of this work was to evaluate the sensitivity of Pacu fingerlings (Piaractus mesopotamicus) by measuring the effects of median lethal concentration (LC50) of atrazine (ATZ - 28.58 mg/L) after acute exposure (up to 96 h). The fish were exposed to the LC50 of ATZ for 96 h (28.58 mg/L) in a static system. During the experiment, the fingerlings were randomly distributed in four glass tanks (50 L) containing dechlorinated water. Four glass tanks were for the control group, and four were for the ATZ-exposed group (n=4 per glass tank), given a total number of 16 animals tested per group. The genotoxicity was evaluated by micronucleus (MN) test in erythrocytes from peripheral blood. Qualitative and semi-quantitative histopathological analyses, and also...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Brazilian ichthyofauna; Kidney lesions; Liver lesions; Micronucleus test; Pacu; Herbicida; Toxidez; Poluição da água; Piaractus mesopotamicus; Water pollution; Atrazine; Oxidative stress; Nephrotoxicity; Hepatotoxicity.
Ano: 2017 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1080546
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Adaptive response: some underlying mechanisms and open questions Genet. Mol. Biol.
Dimova,Evgeniya G.; Bryant,Peter E.; Chankova,Stephka G..
Organisms are affected by different DNA damaging agents naturally present in the environment or released as a result of human activity. Many defense mechanisms have evolved in organisms to minimize genotoxic damage. One of them is induced radioresistance or adaptive response. The adaptive response could be considered as a nonspecific phenomenon in which exposure to minimal stress could result in increased resistance to higher levels of the same or to other types of stress some hours later. A better understanding of the molecular mechanism underlying the adaptive response may lead to an improvement of cancer treatment, risk assessment and risk management strategies, radiation protection, e.g. of astronauts during long-term space flights. In this mini-review...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adaptive response; Oxidative stress; DNA repair up-regulation; DNA-binding proteins; Antioxidant defense system.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000300002
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Algicidal effects of aqueous leaf extracts of neem (Azadirachta indica) on Scenedesmus quadricauda (Turp.) de Brébission Acta Botanica
Chia,Mathias Ahii; Akinsanmi,Jamiu Taiwo; Tanimu,Yahuza; Ladan,Zakari.
The application of synthetic algaecides for the control of algae produces by-products that are sometimes toxic to the environment. There is a need for natural and cheap alternatives to synthetic algaecides. In the present study, we investigated the potential of aqueous crude extract of Azadirachta indica to inhibit the growth of Scenedesmus quadricauda. Phytochemical screening of the extract revealed the presence of groups of bioactive compounds that are capable of inhibiting microalgal growth. Chlorophyll a concentration, dry weight production and cell density of microalga decreased with increasing crude extract concentration. After three days of exposure, the 1000 mg/L extract concentration resulted in complete growth inhibition and cell lysis....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Algaecide; Growth inhibition; Microalgae; Neem; Oxidative stress; Phenotypic plasticity.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-33062016000100001
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Aluminum stress tolerance in potato genotypes grown with silicon Bragantia
Dorneles,Athos Odin Severo; Pereira,Aline Soares; Sasso,Victória Martini; Possebom,Gessieli; Tarouco,Camila Peligrinotti; Schorr,Márcio Renan Weber; Rossato,Liana; Ferreira,Paulo Ademar Avela; Tabaldi,Luciane Almeri.
ABSTRACT Potato cultivation is widespread around the world, being exposed to several abiotic stresses, including soils with high aluminum (Al) availability. Silicon (Si) is recognized for alleviating the stress caused by Al in various plant species. Thus, the aim of this study was to investigate the potential of Si to mitigate the oxidative stress caused by Al in potato genotypes, exhibiting differential sensitivity toward this element. Plants of the Al-sensitive genotype (SMIJ319-7) and Al-tolerant genotype (SMIF212-3) were grown for two weeks in a hydroponic system with the nutrient solution containing combinations of Al (0 and 1.85 mM) and Si (0, 0.5 and 1.0 mM). At the end of the experiment, photosynthetic parameters, pigment content, root and shoot...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Solanum tuberosum; Beneficial elements; Enzyme activity; Oxidative stress; Toxic elements.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0006-87052019000100012
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Ameliorative potential of Ocimum sanctum in chronic constriction injury-induced neuropathic pain in rats Anais da ABC (AABC)
KAUR,GURPREET; BALI,ANJANA; SINGH,NIRMAL; JAGGI,AMTESHWAR S..
The present study was designed to investigate the ameliorative potential of Ocimumsanctum and its saponin rich fraction in chronic constriction injury-induced neuropathic pain in rats. The chronic constriction injury was induced by placing four loose ligatures around the sciatic nerve, proximal to its trifurcation. The mechanical hyperalgesia, cold allodynia, paw heat hyperalgesia and cold tail hyperalgesia were assessed by performing the pinprick, acetone, hot plate and cold tail immersion tests, respectively. Biochemically, the tissue thio-barbituric acid reactive species, super-oxide anion content (markers of oxidative stress) and total calcium levels were measured. Chronic constriction injury was associated with the development of mechanical...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronic constriction injury; Ocimum sanctum; Saponin rich fraction; Calcium; Oxidative stress.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100417
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An association study of FOXO3 variant and longevity Genet. Mol. Biol.
Silva-Sena,Geralda Gillian; Camporez,Daniela; Santos,Lígia Ramos dos; Silva,Aline Sesana da; Sagrillo Pimassoni,Lúcia Helena; Tieppo,Alessandra; Pimentel Batitucci,Maria do Carmo; Morelato,Renato Lírio; Paula,Flavia de.
Abstract Human longevity is a polygenic and multifactorial trait. Pathways related to lifespan are complex and involve molecular, cellular, and environmental processes. In this analytical observational study, we evaluated the relationship between environment factors, oxidative stress status, DNA integrity level, and the association of FOXO3 (rs2802292), SOD2 (rs4880), APOE (rs429358 and rs7412), and SIRT1 (rs2273773) polymorphisms with longevity in oldest-old individuals from southeastern Brazil. We found an association between the FOXO3 GG genotype and gender. While lifestyle, anthropometric, and biochemical characteristics showed significant results, DNA damage and oxidative stress were not related to lifespan. We found that long-lived individuals with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lifespan; SNPs; Environmental factors; Oxidative stress; Genomic damage.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000300386
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Analysis of Myenteric Neurons of the Cecum of Diabetic Rats After Supplementation with Ascorbic Acid International Journal of Morphology
Zanoni,Jacqueline Nelisis; Pereira,Priscila Goncalves Cardoso; dos Santos Pereira,Marli Aparecida.
The objective of this work was to investigate the neuroprotective action of the ascorbic acid over the myenteric neurons in the cecum of Wistar rats, four months after induction of the diabetes mellitus experimental with streptozotocin. Three groups with five rats each were used: C- controls, D- diabetic, DA- diabetic treated with ascorbic acid. For evidentiation of the myenteric neurons was carried out to Giemsa's technique. Were evaluated the areas of cell bodies of 500 neurons in each group studied. The quantitative analysis was carried out in an area of 16.6 mm2 in each cecum studied. In the animals diabetic observed elevation of the glycemia and glycated hemoglobin. The supplementation with ascorbic acid was effective under the myenteric neurons of...
Tipo: Journal article Palavras-chave: Ascorbic acid; Diabetes mellitus; Oxidative stress; Cecum; Streptozotocin.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000200013
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Annona crassiflora Mart. fruit pulp effects on biochemical parameters and rat colon carcinogenesis Ciência e Agrotecnologia
Venâncio,Vinícius Paula; Ferreira,Eric Batista; Brigagão,Maísa Ribeiro Pereira Lima; Paula,Fernanda Borges de Araújo; Barbisan,Luis Fernando; Azevedo,Luciana.
A. crassiflora Mart. a Brazilian savannah fruit, is a source of phytochemical compounds that possess a wide array of biological activities, including free radical scavenging. This native fruit proved to potentialize the mutagenic process in previous in vivo investigations. The aim of the present study was to investigate the effects of A. crassiflora Mart. pulp intake on colonic cell proliferation and on the development of Aberrant Crypt Foci (ACF) in male Wistar rats. The animals were fed with either a commercial diet or a diet supplemented with A. crassiflora Mart. pulp mixed in 1%, 10% or 20% (w/w) for 4 weeks or 20 weeks. The carcinogen 1,2-dimethylhydrazine dihydrochloride (4 doses, 40 mg kg-1 each) was used to induce colonic ACF. After euthanasia, the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aberrant crypt foci; Brazilian savannah; Dimethylhydrazine; Immunohistochemistry; Oxidative stress.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542013000400008
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Anti-inflammatory effect of water extracts obtained from doenjang in LPS-stimulated RAW 264.7 cells Ciênc. Tecnol. Aliment.
LEE,Sang Hyun; LEE,Hyesook; KIM,Jae Cherl.
Abstract The effect of water extracts of doenjang (WED) on cyclooxygenase pathway and cytokine production in lipopolysaccharide (LPS)-treated RAW 264.7 macrophage cells was investigated. WED was fractionated by ultrafiltration into five individual groups of molecular weights. All of the WED fractions significantly inhibited the production of prostaglandin E2 (PGE2) and expression of cyclooxygenase-2 (COX-2) in LPS-stimulated RAW 264.7 macrophages. Furthermore, each of the WED fractions significantly decreased production of pro-inflammatory cytokine such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) (p<0.05). The fraction between 10 to 30 kDa of WED showed the highest inhibition of pro-inflammatory cytokine production, LPS-induced COX-2...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Water extracts of doenjang (WED); Fermented soybean paste; Oxidative stress; Inflammation; Lipopolysaccharide.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612019000400947
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Antioxidant and anti hyperglycemic role of wine grape powder in rats fed with a high fructose diet Biol. Res.
Hernández-Salinas,Romina; Decap,Valerie; Leguina,Alberto; Cáceres,Patricio; Perez,Druso; Urquiaga,Ines; Iturriaga,Rodrigo; Velarde,Victoria.
BACKGROUND: Metabolic syndrome is a growing worldwide health problem. We evaluated the effects of wine grape powder (WGP), rich in antioxidants and fiber, in a rat model of metabolic syndrome induced by a high fructose diet. We tested whether WGP supplementation may prevent glucose intolerance and decrease oxidative stress in rats fed with a high fructose diet. METHODS: Male Sprague-Dawley rats weighing 180 g were divided into four groups according to their feeding protocols. Rats were fed with control diet (C), control plus 20 % WGP (C + WGP), 50 % high fructose (HF) or 50 % fructose plus 20 % WGP (HF + WGP) for 16 weeks. Blood glucose, insulin and triglycerides, weight, and arterial blood pressure were measured. Homeostasis model assessment (HOMA) index...
Tipo: Journal article Palavras-chave: Insulin resistance; Oxidative stress; Metabolic syndrome; Wine grape powder.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100053
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Antioxidant and hepatoprotective effects of ethanolic and ethyl acetate stem bark extracts of Copaifera multijuga (Fabaceae) in mice Acta Amazonica
PEREIRA,Débora Linsbinski; CUNHA,Ana Paula Simões DA; CARDOSO,Cássia Regina Primila; ROCHA,Cláudia Quintino DA; VILEGAS,Wagner; SINHORIN,Adilson Paulo; SINHORIN,Valéria Dornelles Gindri.
ABSTRACT The properties of oil-resin of copaiba, Copaifera multijuga are commonly mentioned in the literature, but there are few studies on extracts from its stem bark. We evaluated the antioxidant effects of ethanolic (EE) and ethyl acetate (EA) crude stem bark extracts from copaiba and compared them to rutin in a paracetamol (PCM)-induced oxidative stress model in mice. All test comparisons differed significantly. Hepatic catalase (CAT) and glutathione-S-transferase (GST) activity decreased in the PCM group, and there was an increase of protein carbonyls in the liver, kidney and brain. However, the protein carbonyls decreased in the liver for the PCM + EE group, in the kidneys for the PCM + EA and PCM + Rutin groups, and in the brain for all treatments....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Oxidative stress; Acute intoxication; Acetaminophen; Copaiba.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672018000400347
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Antioxidant and other biochemical defense responses of Macrotyloma uniflorum (Lam.) Verdc. (Horse gram) induced by high temperature and salt stress Braz. J. Plant Physiol.
Naji,Khalid Mohammed; Devaraj,V. R..
High temperature and salinity are the major ecological factors challenging crop productivity in the arid and semiarid regions of the world. Effects of high temperature (43-45°C) and salt stress (0.6 M) on Macrotyloma uniflorum (Lam.) Verdc. (Horse gram), were evaluated in terms of antioxidants and antioxidant enzymes. Both treatments caused typical stress responses in this tropical leguminosae. Oxidative stress indicators such as H2O2, TBARS, and proline were significantly elevated. Similarly, the antioxidant enzymes superoxide dismutase (SOD; EC 1.15.1.1), guaiacol peroxidase (POX; EC 1.11.1.7) and acid phosphates (AP; EC 3.1.3.2) were significantly elevated while catalase (CAT; EC 1.11.1.6) was reduced. These treatments had contrasting effects on...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant enzymes; Horse gram; Isozymes; Oxidative stress; Salinity; Stress markers.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202011000300002
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Antioxidant defenses of irrigated forage sorghum with saline aquaculture effluent. Repositório Alice
GUIMARÃES, M. J. M.; SIMOES, W. L.; CAMARA, T. de J. R.; SILVA, C. U. de C; WILLADINO, L. G..
The objective of this work was to evaluate the biomass production and antioxidant enzymatic system activity of irrigated forage sorghum with saline aquaculture effluent under different leaching fractions. The experiment was conducted in the Caatinga Experimental Field of the Embrapa Semiarido, in Petrolina, State of Pernambuco, Brazil. The experimental design was a complete randomized block in a split-plot arrangement with four replications, consisting of three forage sorghum varieties (Volumax, F305 and Sudan) and four leaching fractions (0, 5, 10 and 15%). The vegetal materials were collected when the plants were at the soft-dough stage. The biomass production and activity of the enzymes superoxide dismutase, catalase and ascorbate peroxidase were...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Água salina; Sorghum bicolor; Enzimas; Estresse oxidativo; Sorgo forrageiro; Irrigação; Enzymes; Oxidative stress; Sorghum.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1089388
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Antioxidant effect of phycocyanin on oxidative stress induced with monosodium glutamate in rats BABT
Bertolin,Telma Elita; Farias,Daniele; Guarienti,Cíntia; Petry,Fernanda Tais Souza; Colla,Luciane Maria; Costa,Jorge Alberto Vieira.
The objective of this work was to study the antioxidant effect of phycocyanin on the oxidative stress induced by monosodium glutamate in the rats. The tests were performed with 32 rats of Wistar breed, divided into four groups, which were administered saline solution of phycocyanin, monosodium glutamate and monosodium glutamate plus phycocyanin. Sulfhydryl groups and the secondary substances derived from lipid oxidation were determined through the level of TBA. The evaluation of these values and the level of sulfhydryl showed that the administration of phycocyanin presented significant antioxidant effect (p < 0.05) reducing the oxidative stress induced by the monosodium glutamate in vivo.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant; Oxidative stress; Phycocyanin.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000400012
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Antioxidant effect of simvastatin throught oxidative imbalance caused by lisdexamfetamine dimesylate Anais da ABC (AABC)
Eger,Guilherme A.; Ferreira,Vinícius V.; Batista,Camila R.; Bonde,Henrique; Lima,Daniela D. de; Wyse,Angela T.S.; Cruz,Júlia N. da; Rodrigues,André F.; Magro,Débora D. Dal; Cruz,José G.P. da.
The present study aims to directly investigate the behavioral and antioxidant effects of simvastatin in a model of bipolar mania induced by lisdexamfetamine dimesylate. Wistar rats were treated for 30 days with simvastatin. On the 24th day after the start of treatment, each rat was administered lisdexamfetamine dimesylate for 7 days. The results suggest that simvastatin combined with lisdexamfetamine dimesylate induced a significant increased locomotion and lisdexamfetamine dimesylate administration causes an oxidative imbalance determined by an increment in lipid peroxidation, protein oxidation and alterations in the activities of antioxidant enzymes in brain areas; moreover, in the presence of simvastatin, most of these effects were prevented. These...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Amphetamine; Lisdexamfetamine dimesylate; Oxidative stress; Simvastatin.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000100335
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Antioxidant Effects of Biochanin A in Streptozotocin Induced Diabetic Rats BABT
Sadri,Hamideh; Goodarzi,Mohammad Taghi; Salemi,Zahra; Seifi,Morteza.
ABSTRACT Bioflavonoid-containing diets have been reported to be beneficial in diabetes. In the current study, the effect of Biochanin A (BCA) on blood glucose, antioxidant enzyme activities and oxidative stress markers in diabetic rats were investigated. 30 male Wistar rats were divided into five groups. Two of them were selected as control; group1: control (receiving 0.5%DMSO), and group2: Control+BCA (receiving 10 mg/kg.bw BCA). Diabetes was induced in other rats with injection of (55 mg/kg.bw) streptozotocin; group3: diabetic control (receiving 0.5%DMSO), groups 4 and 5 were treated with 10 and 15 mg/kg.bw BCA respectively. After 6 weeks the following results were obtained. Fasting blood glucose (FBG), Triglyceride (TG), total cholesterol (TC), low...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biochanin A; Diabetic rats; Oxidative stress; STZ.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100313
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