Data/hora: 26/07/2024 22:46:01

Provedor de dados: 	Ciência e Tecnologia de Alimentos	
País: 	Brazil	
Título: 	Investigation of cytotoxic and mutagenic effects of Malpighia glabra L. (barbados cherry) fruit pulp and vitamin C on plant and animal test systems	
Autores: 	Düsman,Elisângela; Ferreira,Márcia Flores da Silva; Berti,Alessandra Paim; Mariucci,Rosinete Gonçalves; Mantovani,Mário Sérgio; Vicentini,Veronica Elisa Pimenta.	
Data: 	2012-06-01	
Ano: 	2012	
Palavras-chave: 	Antioxidants; Cytotoxicity; Mutagenesis.	
Resumo: 	Fruits are important sources of nutrients in human diet, and Barbados Cherry (Malpighia glabra L.) is of particular interest due to its high content of antioxidants. Diets rich in fruits and vegetables protect individuals against diseases and cancer, but excessive intake of vitamins may act as pro-oxidant and generate changes in DNA. To evaluate the effect of different in natura (BAN) and frozen (BAF) Barbados Cherry pulp concentrations and synthetic vitamin C in liquid form (VC) on the chromosome level and the cell cycle division, root meristeme cells of Allium cepa L. and bone marrow cells of Wistar rats Rattus norvegicus, were used as test system. In Allium cepa L., BAN, at the highest concentration (0.4 mg.mL-1) and BAF, at the lowest concentration (0.2 mg.mL-1), inhibited cell division, and there was recovery of cell division after the recovery period in water only for BAN. In the Wistar rats, all treatments with Barbados Cherry, either acute or subchronic, were not cytotoxic or mutagenic; only the highest concentration of VC increased significantly the rate of chromosomal abnormalities. The data obtained are important to reinforce the use of Barbados Cherry fruit in the diet.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612012000200030	
Editor: 	Sociedade Brasileira de Ciência e Tecnologia de Alimentos	
Relação: 	10.1590/S0101-20612012005000054	
Formato: 	text/html	
Fonte: 	Food Science and Technology  v.32 n.2 2012	
Fonte: 	info:eu-repo/semantics/openAccess