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Uncovering sub-structure and genomic profiles in across-countries subpopulations of Angus Cattle. Repositório Alice
CARDOSO, D. F.; FERNANDES JÚNIOR, G. A.; SCALEZ, D. C. B.; ALVEZ, A. A. C.; MAGALHÃES, A. F. B.; BRESOLIN, T.; VENTURA, R. V.; LI, C.; OLIVEIRA, M. C. de S.; PORTO NETO, L. R.; CARVALHEIRO, R.; OLIVEIRA, H. N. de; TONHATI, H.; ALBUQUERQUE, L. G..
Highlighting genomic profiles for geographically distinct subpopulations of the same breed may provide insights into adaptation mechanisms to different environments, reveal genomic regions divergently selected, and offer initial guidance to joint genomic analysis. Here, we characterized similarities and differences between the genomic patterns of Angus subpopulations, born and raised in Canada (N?= 382) and Brazil (N = 566). Furthermore, we systematically scanned for selection signatures based on the detection of autozygosity islands common between the two subpopulations, and signals of divergent selection, via FST and varLD tests. The principal component analysis revealed a sub-structure with a close connection between the two subpopulations. The averages...
Tipo: Artigo de periódico Palavras-chave: Autozygosity islands; Rather similar across; Overall genomic diversity; ROH islands; FST; VarLD signals; Angus.
Ano: 2020 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1127803
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Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle. Repositório Alice
PERIPOLLI, E.; STAFUZZA, N. B.; MUNARI, D. P.; LIMA, A. L. F.; IRGANG, R.; MACHADO, M. A.; PANETTO, J. C. do C.; VENTURA, R. V.; BALDI, F.; SILVA, M. V. G. B..
Abstract BACKGROUND: Runs of homozygosity (ROH) are continuous homozygous segments of the DNA sequence. They have been applied to quantify individual autozygosity and used as a potential inbreeding measure in livestock species. The aim of the present study was (i) to investigate genome-wide autozygosity to identify and characterize ROH patterns in Gyr dairy cattle genome; (ii) identify ROH islands for gene content and enrichment in segments shared by more than 50% of the samples, and (iii) compare estimates of molecular inbreeding calculated from ROH (FROH), genomic relationship matrix approach (FGRM) and based on the observed versus expected number of homozygous genotypes (FHOM), and from pedigree-based coefficient (FPED). RESULTS: ROH were identified in...
Tipo: Separatas Palavras-chave: Dairy traits; Inbreeding coefficients; ROH islands; Bos Indicus.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1100275
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