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Effectiveness of highly active antiretroviral therapy using non-brand name drugs in Brazil BJMBR
May,S.B.; Barroso,P.F.; Nunes,E.P.; Barcaui,H.S.; Almeida,M.M.T.; Costa,M.D.; Faulhaber,J.C.; Santoro-Lopes,G.; Schechter,M..
In Brazil, HIV-infected individuals receive drugs (including non-brand name drugs which comprise locally produced generics and drugs that have not been tested in bioequivalence trials) free of charge from the government. The objective of the present study was to evaluate the effectiveness of highly active antiretroviral therapy (HAART) in Rio de Janeiro, Brazil, where non-brand drugs are widely used. For this purpose, we estimated the proportion of subjects with virologic failure (plasma HIV viral load greater than 400 copies/mL at 6 months after initiation of treatment). This was a retrospective cohort study of drug-naive HIV-infected subjects who initiated HAART. Subjects were included in the analysis if they were 18 years of age or older, were treatment...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV/AIDS; Antiretroviral; Non-brand name drugs; Brazil; Virologic failure.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000400014
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