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| Almeida,Flávia Jacqueline; Zaparoli,Mayra Simioni; Moreira,Denise Helena; Cavalcanti,Jaqueline de Souza; Rodrigues,Rosangela; Berezin,Eitan Naaman; Ferreira,João Leandro de Paula; Sáfadi,Marco Aurélio Palazzi; Brígido,Luis Fernando de Macedo. |
| Management of children with HIV/AIDS is specially challenging. Age-related issues do not allow for direct transposition of adult observations to this population. CXCR4 tropism has been associated with disease progression in adults. The geno2pheno web-base is a friendly tool to predict viral tropism on envelope V3 sequences, generating a false positive rate for a CXCR4 prediction. We evaluated the association of HIV-1 tropism prediction with clinical and laboratory outcome of 73 children with HIV/AIDS in São Paulo, Brazil. The CXCR4 tropism was strongly associated with a lower (nadir) CD4 documented during follow-up (p < 0.0001) and with disease severity (clinical event and/or CD4 below 200 cells/mm3) at the last observation, using commonly applied... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV-1; Children; Viral tropism; Disease progression. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000300300 |
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| Berezin,Eitan Naaman; Iazzetti,Marco Antonio. |
| We reviewed the incidence of occult bacteremia, to identify the most frequent etiological agents of bacteremias in otherwise healthy children from one month to 10 years old, who had fever of unknown origin attended at the emergency ward of an urban, university-affiliated pediatric referral center. This was a retrospective medical record review, evaluating children with fever. Data were collected from the initial visit, when blood cultures, hematological properties and hemosedimentation rates were examined. Fever was considered as the highest temperature assessed in the hospital or reported by the responsible adult. Occult bacteremia was discovered in 1.4% of the 1,051 children evaluated, and the most common etiologic agent was Streptococcus pneumoniae.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fever; Streptococcus pneumoniae; Occult bacteremia. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000600007 |
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| Pecchini,Rogério; Berezin,Eitan Naaman; Souza,Maria Cândida; Vaz-de-Lima,Lourdes de Andrade; Sato,Neuza; Salgado,Maristela; Ueda,Mirthes; Passos,Saulo Duarte; Rangel,Raphael; Catebelota,Ana. |
| Background: Human parainfluenza viruses account for a significant proportion of lower respiratory tract infections in children.Objective: To assess the prevalence of Human parainfluenza viruses as a cause of acute respiratory infection and to compare clinical data for this infection against those of the human respiratory syncytial virus.Methods: A prospective study in children younger than five years with acute respiratory infection was conducted. Detection of respiratory viruses in nasopharyngeal aspirate samples was performed using the indirect immunofluorescence reaction. Length of hospital stay, age, clinical history and physical exam, clinical diagnoses, and evolution (admission to Intensive Care Unit or general ward, discharge or death) were assessed.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Parainfluenza; Paramyxoviridae infections; Respiratory tract infections; Respiratory virus. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000400358 |
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