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| Cunha-Silva,Marlone; Marinho,Fábio R.T.; Oliveira,Paulo F.; Lopes,Tirzah M.; Sevá-Pereira,Tiago; Lorena,Sonia L.S.; Almeida,Jazon R.S.. |
| Abstract Background: Chronic hepatitis B is a major cause of cirrhosis, and the natural history of the disease has several clinical stages that should be thoroughly understood for the implementation of proper treatment. Nonetheless, curing the disease with antiviral treatment remains a challenge. Aims: To describe the clinical course, response to treatment, and poor prognostic factors in 247 hepatitis B virus chronic infection patients treated in a tertiary hospital in Brazil. Methods: This was a retrospective and observational study, by analyzing the medical records of HBV infected patients between January 2000 and January 2015. Results: Most patients were male (67.2%) and 74.1% were HBeAg negative. Approximately 41% had cirrhosis and 8.5% were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis B; Clinical stages; Treatment; Liver cirrhosis; Hepatocellular carcinoma. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000400441 |
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| Vezozzo,Denise Cerqueira Paranaguá; Mendes-Correa,Maria Cassia; Cunha-Silva,Marlone; Alvarado-Mora,Mónica Viviana; França,João Ítalo Dias; Sebba,José Luiz; Nicodemo,Antonio Carlos; Oliveira,Claudia P.M.S.; Carrilho,Flair José. |
| OBJECTIVES: Progression of hepatic fibrosis is accelerated in patients co-infected with human immunodeficiency virus and hepatitis C virus compared to hepatitis C virus mono-infected patients. This study aimed to compare ultrasound features and selected clinical and biochemical variables between patients with human immunodeficiency virus/hepatitis C virus co-infection (n = 16) versus hepatitis C virus mono-infection (n = 16). METHODS: Each patient underwent abdominal ultrasound, and a specific evaluation was performed in order to detect findings consistent with chronic liver disease. Characterization of spleen size, liver structural pattern, diameter of the portal, spleen, and mesenteric veins was based on classical ultrasound parameters. Propensity score... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ultrasonography; HIV/HCV co-infection; Hepatomegaly; Liver size; Cirrhosis. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000200006 |
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