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Duration-controlled swimming exercise training induces cardiac hypertrophy in mice BJMBR
Evangelista,F.S.; Brum,P.C.; Krieger,J.E..
Exercise training associated with robust conditioning can be useful for the study of molecular mechanisms underlying exercise-induced cardiac hypertrophy. A swimming apparatus is described to control training regimens in terms of duration, load, and frequency of exercise. Mice were submitted to 60- vs 90-min session/day, once vs twice a day, with 2 or 4% of the weight of the mouse or no workload attached to the tail, for 4 vs 6 weeks of exercise training. Blood pressure was unchanged in all groups while resting heart rate decreased in the trained groups (8-18%). Skeletal muscle citrate synthase activity, measured spectrophotometrically, increased (45-58%) only as a result of duration and frequency-controlled exercise training, indicating that endurance...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Exercise training; Swimming; Cardiac hypertrophy; Mice; Myocardium.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001200018
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Loss of resting bradycardia with detraining is associated with intrinsic heart rate changes BJMBR
Evangelista,F.S.; Martuchi,S.E.D.; Negrão,C.E.; Brum,P.C..
The mechanisms underlying the loss of resting bradycardia with detraining were studied in rats. The relative contribution of autonomic and non-autonomic mechanisms was studied in 26 male Wistar rats (180-220 g) randomly assigned to four groups: sedentary (S, N = 6), trained (T, N = 8), detrained for 1 week (D1, N = 6), and detrained for 2 weeks (D2, N = 6). T, D1 and D2 were treadmill trained 5 days/week for 60 min with a gradual increase towards 50% peak VO2. After the last training session, D1 and D2 were detrained for 1 and 2 weeks, respectively. The effect of the autonomic nervous system in causing training-induced resting bradycardia and in restoring heart rate (HR) to pre-exercise training level (PET) with detraining was examined indirectly after...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Exercise training; Cardiac autonomic balance; Heart rate; Peak oxygen uptake; Detraining.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700018
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Physical training prevents body weight gain but does not modify adipose tissue gene expression BJMBR
Higa,T.S.; Bergamo,F.C.; Mazzucatto,F.; Fonseca-Alaniz,M.H.; Evangelista,F.S..
The relationship of body weight (BW) with white adipose tissue (WAT) mass and WAT gene expression pattern was investigated in mice submitted to physical training (PT). Adult male C57BL/6 mice were submitted to two 1.5-h daily swimming sessions (T, N = 18), 5 days/week for 4 weeks or maintained sedentary (S, N = 15). Citrate synthase activity increased significantly in the T group (P < 0.05). S mice had a substantial weight gain compared to T mice (4.06 ± 0.43 vs 0.38 ± 0.28 g, P < 0.01). WAT mass, adipocyte size, and the weights of gastrocnemius and soleus muscles, lung, kidney, and adrenal gland were not different. Liver and heart were larger and the spleen was smaller in T compared to S mice (P < 0.05). Food intake was higher in T than S mice...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Swimming training; Energy balance; White adipose tissue; WAT gene expression; C57BL/6 mice.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001000016
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