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Registros recuperados: 11
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BJPS as strategical for Pharmaceutical Sciences BJPS
Ferreira,Elizabeth Igne.
Tipo: Info:eu-repo/semantics/article
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000100001
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Celebrating the 70th Anniversary with increased international visibility! BJPS
Ferreira,Elizabeth Igne.
Tipo: Info:eu-repo/semantics/article
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000100001
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Chalcones and N-acylhydrazones: direct analogues? Exploratory data analysis applied to potential novel antileishmanial agents BJPS
Rando,Daniela Gonçalves; Giarolla,Jeanine; Pasqualoto,Kerly Fernanda Mesquita; Ferreira,Elizabeth Igne.
Leishmaniasis is an important health and social problem for which there is limited effective therapy. Chalcones and N-acylhydrazones have been studied as promising antileishmanial agents in enzymatic inhibition and in vitro assays. Since these chemical classes of compounds also resemble each other structurally, it would be useful to investigate whether they share direct analogy. Exploratory data analysis was applied to a library of chalcones and nitrated N-acylhydrazones assayed against Leishmania donovani to investigate their similarity. Under the conditions applied in the present study, the two classes did not present functional or structural analogy.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chalcones; N-acylhydrazones; Antileishmanial agents; Leishmaniasis; Chemometrics.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200019
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Chemistry and pharmaceutical sciences always together BJPS
Ferreira,Elizabeth Igne.
Tipo: Info:eu-repo/semantics/article
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300001
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Internationalizing Brazilian Pharmaceutical Sciences BJPS
Ferreira,Elizabeth Igne.
Tipo: Info:eu-repo/semantics/other
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000300001
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One year of BJPS! BJPS
Ferreira,Elizabeth Igne.
Tipo: Info:eu-repo/semantics/other
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400001
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Pharmaceutical Sciences is in the agenda! BJPS
Ferreira,Elizabeth Igne.
Tipo: Info:eu-repo/semantics/other
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000400001
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Prodrugs available on the Brazilian pharmaceutical market and their corresponding bioactivation pathways BJPS
Parise Filho,Roberto; Polli,Michelle Carneiro; Barberato Filho,Silvio; Garcia,Monique; Ferreira,Elizabeth Igne.
The aim of this paper was to emphasize the importance of prodrug design to therapy, by examining examples available on the Brazilian pharmaceutical market. The principles of prodrug design are briefly discussed herein. Examples of prodrugs from many important therapeutic classes are shown and their advantages relative to the drugs they are derived from are also discussed. Considering the importance of these therapeutic classes, from both therapy and economic standpoints, prodrug design is a very valuable aspect in the research of new drugs and for the pharmaceutical industry as a whole.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Prodrug design; Molecular modification; Drug development.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300003
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Reverse phase high-performance liquid chromatography for quantification of hydroxymethylnitrofurazone in polymeric nanoparticles BJPS
Monteiro,Lis Marie; Tavares,Guilherme Diniz; Ferreira,Elizabeth Igne; Consiglieri,Vladi Olga; Bou-Chacra,Nadia Araci; Löbenberg,Raimar.
Hydroxymethylnitrofurazone (NFOH) is a new compound with potential leishmanicidal and trypanocidal activity. Despite its effectiveness, the formulators have to overcome its poor aqueous solubility. Recently, polymeric nano-scale drug delivery systems have proposed for the treatment of neglected diseases. As several studies have confirmed the advantages of such formulations, and this approach provides new analytical challenges, including the need to detect trace amounts of the drug. A suitable method was developed and validated for NFOH determination bound to poly (n-butylcyanoacrylate) (PBCA) nanoparticles. The chromatographic separation was achieved using a C18 column maintained at 25 ºC and an isocratic mobile phase consisting of water and acetonitrile:...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hydroxymethylnitrofurazone/determinação; Nanoparticle; High-performance liquid chromatography/reverse phase/quantitative analysis; Poly(n-butylcyanoacrylate)/nanoparticles/encapsulation.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300561
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Twenty years of LASSBio, the laboratory of evaluation and synthesis of bioactive substances! BJPS
Ferreira,Elizabeth Igne.
Tipo: Info:eu-repo/semantics/other
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000300005
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XII National Meeting of Pharmaceutical Chemistry Professors: could we have now a subarea of Pharmaceutical and Medicinal Chemistry in the CNPq Pharmacy Comittee? BJPS
Ferreira,Elizabeth Igne; Barreiro,Eliezer L.; Andrade,Carolina Horta.
Tipo: Info:eu-repo/semantics/other
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000100001
Registros recuperados: 11
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