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Registros recuperados: 12
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An extract of a formula used in the traditional chinese medicine (Buzhong Yi Qi Wan) alters the labeling of blood constituents with technetium-99m BABT
Giani,Tania Santos; Paoli,Severo de; Presta,Giuseppe Antonio; Maiworm,Adalgisa Ieda; Santos-Filho,Sebastião David; Brandão-Neto,José; Medeiros,Aldo da Cunha; Fonseca,Adenilson de Souza da; Bernardo-Filho,Mario.
Buzhong Yi Qi Wan (Buzhong) is a medicinal herb widely used in Traditional Chinese Medicine to treat the digestive and circulatory systems. Red blood cell and plasma proteins labeled with technetium-99m (99mTc) are used in nuclear medicine. The aim of this work was to investigate the effects of an aqueous Buzhong extract on the labeling of blood constituents with 99mTc. Heparinized blood (Wistar rats) was incubated in vitro with different Buzhong extract concentrations and 99mTc-labeling was performed. Plasma (P) and blood cells (BC) were separated and soluble (SF-P, SF-BC) and insoluble (IF-P, IF-BC) fractions were isolated. The radioactivity on blood constituents was determined and the percentage of incorporated radioactivity (%ATI) was calculated....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Technetium-99m; Red blood cell; Oxidant agent; Radiobiocomplex; Plasma proteins; Buzhong Yi Qi Wan.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600013
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Atividade antibacteriana e cicatrizante do óleo de buriti Mauritia flexuosa L. Ciência Rural
Batista,Jael Soares; Olinda,Roberio Gomes; Medeiros,Vitor Brasil; Rodrigues,Carla Monadeli Filgueira; Oliveira,Andréia Freitas; Paiva,Erika Souza; Freitas,Carlos Iberê Alves; Medeiros,Aldo da Cunha.
O objetivo deste estudo foi avaliar a atividade antibacteriana in vitro e cicatrizante do óleo de buriti (M. flexuosa) em feridas realizadas em ratos (Rattus norvegicus albinus). Para a avaliação antibacteriana in vitro, foram utilizados cinco patógenos bacterianos incluindo espécies gram-positivas e espécies gram-negativas mediante o uso do método de difusão em ágar. Para a avaliação da atividade cicatrizante, foram utilizados 40 ratos da linhagem Wistar, divididos em dois grupos: o grupo I, composto por 20 ratos com feridas cutâneas, tratados com aplicação tópica do creme base com 10% de óleo de buriti, e o grupo II, controle, com o mesmo número de animais que receberam a aplicação tópica do creme base. A aplicação do produto foi realizada em feridas...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ação antibacteriana; Processo cicatricial; Ferida; Óleo de buriti; M. flexuosa.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782012000100022
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Consequences of the magnetic field, sonic and radiofrequency waves and intense pulsed light on the labeling of blood constituents with technetium-99m BABT
Meyer,Patricia Froes; Santos-Filho,Sebastião David; Ronzio,Oscar Ariel; Bonelli,Ludmila; Fonseca,Adenilson de Souza da; Costa,Iris do Ceu Clara; Brandão Neto,José; Medeiros,Aldo da Cunha; Bernardo-Filho,Mario.
Sources of magnetic field, radiofrequency and audible sonic waves and pulsed light have been used in physiotherapy to treat different disorders. In nuclear medicine, blood constituents(Bl-Co) are labeled with technetium-99m (99mTc) are used. This study evaluated the consequences of magnetic field, radiofrequency and audible sonic waves and intense pulsed light sources on the labeling of Bl-Co with 99mTc. Blood from Wistar rats was exposed to the cited sources. The labeling of Bl-Co with 99mTc was performed. Blood not exposed to the physical agents was used(controls). Data showed that the exposure to the different studied sources did not alter significantly (p>0.05) the labeling of Bl-Co. Although the results were obtained with animals, the data suggest...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Blood constituents; Magnetic field; Sonic and radiofrequency waves; Technetium-99m.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600014
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Effect of a peel passion fruit flour (Passiflora edulis f. flavicarpa) extract on the labeling of blood constituents with technetium-99m and on the morphology of red blood cells BABT
Rebello,Bernardo Machado; Moreno,Silvana Ramos Farias; Ribeiro,Camila Godinho; Neves,Rosane de Figueiredo; Fonseca,Adenilson de Souza da; Caldas,Luis Querino de Araújo; Bernardo-Filho,Mario; Medeiros,Aldo da Cunha.
Passiflora edulis f. flavicarpa (maracuja) is a fruit consumed in Brazil and worldwide. Blood constituents labeled with technetium-99m (99mTc) are used in nuclear medicine. The effect of P. flavicarpa extract on the radiolabeling of blood constituents and on red blood cells morphology was evaluated. Blood samples from Wistar rats was incubated with P. flavicarpa extract. After that, the labeling of blood constituents with 99mTc was carried out. Samples of plasma and blood cells were precipitated with trichloroacetic acid to isolate the soluble and insoluble fractions of plasma and blood cells. The radioactivity in each fractions was counted and the percentage of radioactivity was determined. Blood smears were also prepared to morphological evaluation and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Labeling; Blood; Passiflora edulis f. flavicarpa; Radiobiocomplexes; Technetium-99m.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600019
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Effect of an Arctium lappa (burdock) extract on the labeling of blood constituents with technetium-99m and on the morphology of the red blood cells BABT
Neves,Rosane de Figueiredo; Moreno,Silvana Ramos Farias; Rebello,Bernardo Machado; Caldas,Luiz Querino de Araújo; Fonseca,Adenilson de Souza da; Bernardo-Filho,Mario; Medeiros,Aldo da Cunha.
Arctium lappa (burdock) has been used to treat inflammatory processes. Blood constituents labeled with technetium-99m (99mTc) have been utilized in nuclear medicine. It was evaluated the influence of a burdock extract on the labeling of blood constituents with 99mTc and on the morphometry of red blood cells. Blood samples from Wistar rats were incubated with burdock extract and the radiolabeling procedure was carried out. Plasma and blood cells, soluble and insoluble fractions of plasma and blood cells were separated. The radioactivity in each fraction was counted and the percentages of radioactivity (%ATI) were determined. Morphology and morphometric (perimeter/area ratio) measurements of red blood cells (RBC) were performed. The incubation with burdock...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Arctium lappa; Technetium-99m; Blood constituents; Morphometry.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600021
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Effect of an extract of Artemisia vulgaris L. (Mugwort) on the in vitro labeling of red blood cells and plasma proteins with technetium-99m BABT
Terra,Danielle Amorim; Amorim,Lúcia de Fátima; Catanho,Maria Tereza Jansen de Almeida; Fonseca,Adenilson de Souza da; Santos-Filho,Sebastião David; Brandão-Neto,José; Medeiros,Aldo da Cunha; Bernardo-Filho,Mario.
The aim of this work was to evaluate the effect of an extract of the Artemisia vulgaris L. (mugwort) on the labeling of blood constituents with technetium-99m (99mTc). Blood samples from Wistar rats were incubated with a mugwort extract and the radiolabeling of blood constituents was carried out. Plasma and blood cells were separated by centrifugation. Aliquots of plasma and blood cells were also precipitated with trichloroacetic acid and centrifuged to isolate soluble and insoluble fractions of plasma and blood cells. Radioactivity in each fraction was counted and the percentages of radioactivity (%ATI) was calculated. Mugwort extract decreased significantly (p<0.05) the %ATI on the blood compartments and on the blood cells proteins (insoluble...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Artemisia vulgaris L.; Technetium-99m; Blood constituents; Labeling.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600015
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Effect of medicinal plants on the parasitemia of Trypanosoma cruzi and on the biodistribution of sodium pertechnetate (Na99mTcO4) BABT
Silva,Roseane Pereira da; Holanda,Cecília Maria de Carvalho Xavier; Barbosa,Vanessa Santos de Arruda; Oliveira,Daniel Pereira de; Lima,Natália Alves; Câmara,Antônia Cláudia Jácome da; Medeiros,Aldo da Cunha; Constantino,Maria Helena Spyrides.
Artemisia vulgaris (AV) is an antihelmintic and antimalarial drug; Aloe vera(babosa) acts as antidiabetic, laxative and anti-inflammatory;Benznidazole (BZ) is a trypanocidal of Trypanosoma cruzi (TC). Technetium-99m (99mTc) has been used in nuclear medicine to obtain diagnostic images. This study evaluated the plant effects in TC parasitemia and on the biodistribution of 99mTc in mice. Twenty mice were infected by TC. At the peak of parasitemia, 5 mice received babosa; 5 received AV and 5 received BZ. The parasitemia was determined at 0, 2, 4 and 6 h of drugs administration. Five infected mice without drugs, 5 mice without TC and the group treated with AV, received 99mTc. The radioactivity was calculated. Infected mice that received babosa reduced...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aloe vera; Artemisia vulgaris; Technetium-99m; Trypanosoma cruzi; Parasitemia; Biodistribution.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700034
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Effect of paclitaxel (Taxol®) on the biodistribution of sodium pertechnetate (Na99mTcO4) in female Wistar rats BABT
Holanda,Cecília Maria de Carvalho Xavier; Oliveira,Elias Herculano de; Rocha,Louisianny Guerra da; Barbosa,Vanessa Santos de Arruda; Spyrides,Maria Helena Constantino; Aragão,Cícero Flávio Soares; Medeiros,Aldo da Cunha.
The evidence that natural or synthetic drugs can affect the biodistribution of radiopharmaceuticals (radiobiocomplexes) in setting of nuclear medicine clinic is already known. We studied the effect of Paclitaxel, an anti-neoplastic agent for the treatment of solid tumors, on the biodistribution of Na99mTcO4 in female rats. Paclitaxel (1mg/mL/week) was administered into animals in single dose during 3 weeks, with interval of 1 week among them. The control group received NaCl 0.9% solutions by the same via. One hour after the last dose, it was injected Na99mTcO4 in the animals. The percentage of activity per gram (%ATI/g) and biochemical and hematological determinations were performed. A significant increase were found in alanine aminotransferase, aspartate...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Paclitaxel; Drug interaction; Radiopharmaceuticals; Na99mTcO4; Antitumoral drug; Cancer.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700031
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Effects of Chrysobalanus icaco on the labeling of blood constituents with technetium-99m and on the shape of the red blood cells BABT
Presta,Giuseppe Antonio; Santos-Filho,Sebastião David; Paoli,Severo de; Giani,Tania Santos; Maiworm,Adalgisa Ieda; Brandão-Neto,José; Medeiros,Aldo da Cunha; Fonseca,Adenilson de Souza da; Bernardo-Filho,Mario.
Chrysobalanus icaco (abajeru; C.icaco) is recommended in the treatment of diabetes and other clinical disorders. Blood constituents labeled with technetium-99m (99mTc) are used in nuclear medicine. The aim of this study was to verify the effects of an abajeru extract on the labeling of blood constituents with 99mTc and on the shape of red blood cells (RBC). Blood samples(Wistar rats) were incubated with abajeru extract and the labeling of blood constituents with 99mTc and morphology of RBC were carried out. The results showed significant (P<0.05) alteration of labeling of blood constituents with 99mTc and the morphometry (perimeter/area ratio) of the RBC in presence of the extract. These data suggest that this abajeru extract could alter the labeling of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Red blood cells; Technetium-99m; Morphometry; Chrysobalanus icaco.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600018
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Effects of clove (Caryophyllus aromaticus L.) on the labeling of blood constituents with technetium-99m and on the morphology of red blood cells BABT
Paoli,Severo de; Giani,Tania Santos; Presta,Giuseppe Antonio; Pereira,Marcia Oliveira; Fonseca,Adenilson de Souza da; Brandão-Neto,José; Medeiros,Aldo da Cunha; Santos-Filho,Sebastião David; Bernardo-Filho,Mário.
Clove (Caryophyllus aromaticus L.) has been used for clinical procedures. Blood constituents labeled with technetium-99m (99mTc) are used in nuclear medicine. The aim of this work was to evaluate the effects of clove extract on the labeling blood constituents with 99mTc and on the morphology of red blood cells. Blood samples were incubated with clove, stannous chloride and 99mTc. Plasma, blood cells, insoluble fractions of plasma and blood cells were separated. The radioactivity was counted and percentage of radioactivity (%ATI) to each blood fraction was calculated. The shape and morphometric parameter (perimeter/area ratio) were evaluated. Clove extract altered significantly (p<0.05) the %ATI of blood constituents and the shape of red blood cells...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Technetium-99m; Blood constituents; Red blood cells; Morphology; Caryophyllus aromaticus L.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600022
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Evaluation of the effect of an extract of sabugueiro (Sambucus australis) on the labeling of blood constituents with technetium-99m BABT
Ribeiro,Camila Godinho; Rebello,Bernardo Machado; Neves,Rosane de Figueiredo; Santos-Filho,Sebastião David; Fonseca,Adenilson de Souza da; Medeiros,Aldo da Cunha; Bernardo-Filho,Mario; Catanho,Maria Teresa Jansem de Almeida.
Sambucus australis (sabugueiro) has been used to treat inflammatory and rheumatologic disorders. Blood constituents labeled with technetium-99m (99mTc) have been used in nuclear medicine to obtain diagnostic images. The aim of this work was to evaluate the effect of a sabugueiro extract on the labeling of blood cells with 99mTc. Blood samples from Wistar rats were incubated with sabugueiro extract and the radiolabeling assay of blood constituents was carried out. After centrifugation, samples of plasma and blood cells were separated. Aliquots of plasma and blood cells were precipitated with trichloroacetic acid and centrifuged to isolate soluble and insoluble fractions. The radioactivity in each fraction was counted and the percentage of activity (%ATI)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sambucus australis; Blood constituents; Technetium-99m.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600020
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Relationship between oxidative stress and diabetic osteopenia in premenopausal rats BJPS
Duarte,Valéria Morgiana Gualberto; Rodrigues,Alanna de Sousa; Rezende,Luciana Augusto de; Ramos,Ana Maria de Oliveira; Souza,Rodrigo Medeiros de; Freire Neto,Francisco Paulo; Medeiros,Aldo da Cunha; Brandão Neto,José; Almeida,Maria das Graças; Rezende,Adriana Augusto de.
The relationship between lipid peroxidation, antioxidant defense and diabetic osteopenia remains unclear. This study evaluated the relationship among lipid peroxidation index, antioxidant defense parameters and bone metabolism in a premenopausal diabetic model using measures including thiobarbituric acid-reactive substances concentration (TBARS) and reduced glutathione (GSH) content in brain homogenates, histomorphometric analysis, biomechanical testing and bone mineral density (BMD). Female Wistar rats with regular estrous cycle were divided into two groups: Group 1: control rats (n = 15) and Group 2: diabetic rats (n = 15). Diabetes was induced by alloxan and confirmed by glycemia &gt;250 mg/dL. The lipid peroxidation index, measured by TBARS...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Oxidative stress; Lipid peroxidation; Diabetes mellitus; Diabetic osteopenia/experimental study.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300018
Registros recuperados: 12
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