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Registros recuperados: 3
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Celecoxib/PLGA Suprime Angiogénesis y Metástasis Pulmonar de un Cáncer Mamario Murino Experimental International Journal of Morphology
Roa,Ignacio; Cantín,Mario; Muñoz,Mariela; Rosas,Carlos; Lemus,David.
La angiogénesis y metástasis son eventos esenciales en el proceso de invasión tumoral. Su relación íntima los hace buenos blancos en la terapia antitumoral. El objetivo fue analizar el patrón de metástasis pulmonar y angiogénesis, luego de la aplicación del antiangiogénico Celecoxib microencapsulado en ácido poli(láctico-co-glicólico) en ratones. Se utilizó un modelo de tumor experimental, inducido por células TA3-MTX-R, en 18 ratones, separados en 3 grupos de 6 animales, los cuales fueron tratados con dos presentaciones de Celecoxib en administración intramuscular (Grupo Control; Grupo Cx 1000 ppm y Grupo Cx 1000 ppm+PLGA). Los ratones fueron sacrificados y procesados histológicamente para ser teñidos con H&E y Tricrómico de Arteta. El estudio reveló...
Tipo: Journal article Palavras-chave: Angiogénesis; Metástasis; Pulmón; Cáncer; Celecoxib; PLGA.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100048
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Mandibular Condyle Repair after Partial Condylectomy in Patients with Active Condylar Hyperplasia International Journal of Morphology
Olate,Sergio; Cantín,Mario; Palmieri,Celso; Alister,Juan Pablo; Muñoz,Mariela; de Moraes,Márcio.
The different aspects of unilateral condylar hyperplasia have been studied and continue to be controversial; nevertheless, treatment based on condylectomy has been established as part of the working protocol. The aim of this investigation was to identify the bone repair observed in surgically treated condyles after 1 year using cone beam computed tomography (CBCT). Nine subjects were included in this study (6 female and 3 male) with an average age of 18.5 years. They had been diagnosed with active unilateral condylar hyperplasia using SPECT, clinical follow-up of progressive facial asymmetry and CBCT. Patients underwent exclusive condylectomy surgery with a piezoelectric system without disc replacement, orthognatic surgery or any other type of adjunct...
Tipo: Journal article Palavras-chave: Condylectomy; Bone remodeling; Condylar hyperplasia.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200054
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Soft and Hard Tissue Relations in Facial Asymmetry International Journal of Morphology
Olate,Sergio; Cantín,Mario; Muñoz,Mariela; Vásquez,Bélgica.
The aim of this study was to determine the relations between hard and soft tissues in subjects with facial asymmetry. Included were subjects aged between 15 and 35 years who presented a chin deviation greater than 5 mm from the midline and a unilateral posterior crossbite. Cone beam computed tomography was used to determine the measurements, positioning them on the three spatial planes; then, 5 bilateral bone points were selected on the coronal image, and parallel measurements were taken to determine the range between the bone point and the most lateral soft tissue point. The statistical analysis was done using the Shapiro-Wilk test, presenting normality in the sample distribution and Levene's test, considering a value of p < 0.05 to obtain significant...
Tipo: Journal article Palavras-chave: Facial asymmetry; Facial analysis; Soft tissues.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000300039
Registros recuperados: 3
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