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	Provedor de dados BJPS (2) Autor Pereira,Gislaine Ribeiro (2) Perissinato,Aline Gravinez (2) Ruela,André Luís Morais (2) Araújo,Magali Benjamim (1) Figueiredo,Eduardo Costa (1) Lima,Ana Carolina Zogbi (1) Lino,Mônica Esselin de Sousa (1) Mudrik,Paula Silva (1) Mais... Palavra-chave Nicotine/release and skin permeation (1) Skin absorption/effects/study (1) Skin absorption/topical formulations (1) Skin absorption/transdermal formulations (1) Skin absorptions/enhancers. (1) Skin permeation (1) Transdermal delivery patches/evaluation (1) Transdermal formulations/nicotine delivery systems (1) Vertical diffusion cell (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2016 (1) 2013 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Evaluation of skin absorption of drugs from topical and transdermal formulations BJPS Ruela,André Luís Morais; Perissinato,Aline Gravinez; Lino,Mônica Esselin de Sousa; Mudrik,Paula Silva; Pereira,Gislaine Ribeiro. ABSTRACT The skin barrier function has been attributed to the stratum corneum and represents a major challenge in clinical practice pertaining to cutaneous administration of drugs. Despite this, a large number of bioactive compounds have been successfully administered via cutaneous administration because of advances in the design of topical and transdermal formulations. In vitro and in vivo evaluations of these novel drug delivery systems are necessary to characterize their quality and efficacy. This review covers the most well-known methods for assessing the cutaneous absorption of drugs as an auxiliary tool for pharmaceutical formulation scientists in the design of drug delivery systems. In vitro methods as skin permeation assays using Franz-type... Tipo: Info:eu-repo/semantics/article Palavras-chave: Skin absorption/effects/study; Skin absorption/topical formulations; Skin absorption/transdermal formulations; Skin absorptions/enhancers.. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000300527 In vitro evaluation of transdermal nicotine delivery systems commercially available in Brazil BJPS Ruela,André Luís Morais; Figueiredo,Eduardo Costa; Perissinato,Aline Gravinez; Lima,Ana Carolina Zogbi; Araújo,Magali Benjamim; Pereira,Gislaine Ribeiro. The aim of this study was to develop and validate a method for evaluating the release and skin permeation from transdermal nicotine patches using the vertical diffusion cell (VDC). The VDC is an experimental apparatus employed in research, development, and the pharmaceutical field because it can simulate conditions closest to those established in clinical trials. Two transdermal nicotine delivery systems marketed in Brazil to release 14 mg over 24 hours were evaluated. Release studies were carried out using a regenerated cellulose dialysis membrane and permeation studies were carried out using excised porcine ear skin. The results indicated that nicotine release from both evaluated patches follows Higuchi's release kinetics, while skin permeation studies... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nicotine/release and skin permeation; Transdermal delivery patches/evaluation; Vertical diffusion cell; Skin permeation; Transdermal formulations/nicotine delivery systems. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000300020 Registros recuperados: 2 Primeira ... 1 ... Última

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