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| Torki,Akram; Khalaji-Pirbalouty,Valiallah; Lorigooini,Zahra; Rafieian-Kopaei,Mahmoud; Sadeghimanesh,Arezo; Rabiei,Zahra. |
| Abstract Stroke is the third leading cause of mortality and disability in industrial countries. Treatment with herbs with antioxidant properties has been reported to be an alternative to the conventional treatments. This study was conducted to investigate the effect of Anchusa italica extract on hippocampal injury induced by transient global cerebral ischemia and reperfusion in the rat. To do so, 50 rats were randomly assigned to five groups; control, sham, ischemia, and 50 or 100 mg/kg of Anchusa italica treated animals. Ischemia was induced by occlusion of carotid artery for 30 minutes. Afterward, behavioral tests and biochemical analyses were conducted. Induction of ischemia/reperfusion caused a decline in learning and passive avoidance memory in rats.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Boraginaceae/phytochemistry; Brain ischemia; Spatial memory/drug effects; Malondialdehyde/pharmacology; Neuroprotection/drug effects; Lipidic peroxidation/drug effects; Antioxidant capacity; Passive avoidance memory.. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100613 |
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| Rabiei,Zahra; Setorki,Mahbubeh. |
| Depression is one of the most common psychiatric disorders with a prevalence of 15%-25%. Monoamine aminotransferases, in particular, norepinephrine, serotonin, and dopamine, change in the brain of depressed people. Adiantum capillus-veneris is one of the species of the maidenhair fern genus that have traditionally been used to treat cough, cold symptoms, and local hair loss.In this experimental study, white male rats weighing 250-300 g were assigned to 5 groups of 10 each; group 1: Receiving normal saline; groups 2-4: Receiving A.capillus-veneris extract at 50, 100, and 200 mg/kg, respectively; and group 5: Receiving fluoxetine at 10 mg/kg. Chronic unpredictable stress (CUS) was induced by 3-week exposure to chronic stress. The forced swim test and plus... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Adiantum capillus-veneris /extract/effects; Forced swim test.Anti-anxiety.. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100554 |
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| Salehi,Azadeh; Rabiei,Zahra; Setorki,Mahbubeh. |
| Learning and memory play main roles in daily life of human, and memory represents the basis of all trainings and learning. The aim of the current study is to investigate the effects of gallic acid and physical exercise on the levels of passive avoidance memory in rat. In this experimental study, 46 rats weighing 200-300 g were randomLy divided to six groups of eight each: including control group, groups treated with 10 and 20 mg/kg gallic acid, group undergoing physical exercise alone, and groups both undergoing physical exercise and treated with 10 and 20 mg/kg gallic acid. The interventions continued for 10 days. After the intervention, passive avoidance memory was measured by shuttle box, blood samples were taken, and serum and brain antioxidant... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gallic Acid/adverse effects; Learning/drug effects; Memory/drug effects; Physical Exercise/physiology; MDA; Avoidance Learning/drug effects; Exercise/physiology; Rats/physiology; Malondialdehyde/analysis. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100568 |
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