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Intraoperative topical administration of mitomycin C, in different concentrations, on the cicatrization of mioplasties of the dorsal rectus of rabbits Ciência Rural
Mamede,Fabrício Villela; Martins,Bianca da Costa; Souza,Ana Letícia Groszewicz; Brunelli,Adriana Torrecilhas Jorge; Pontin,Karina; Soares,Edson Garcia; Albuquerque,Sérgio de; Laus,José Luiz.
Myoplasties of the extraocular muscle may cause adhesions between the operated muscle and the adjacent tissues, commonly generating cicatricial strabismus. With the purpose of reducing to a minimum the occurrence of adhesion, the effects of mitomycin C, an antifibrotic agent, were studied in concentrations of 0.008%, 0.02%, and 0.04% applied during intraoperative of myoplasties of the superior rectus muscle of rabbits. Fifty six animals were divided in five groups. During the postoperative, the operated areas were washed with physiological solution. Eye drop instillation to prevent inflammation and bacterial infection were used. The method to analyze the results consisted of clinical and histological evaluation and statistical analyzes. We also evaluated...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adhesions; Mitomycin C; Myoplasty; Eye.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782008000100021
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