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| Gatto,Larissa Junqueira; Fabri,Natasha Tiemi; Souza,Angela Maria de; Fonseca,Natasha Stopinski Triaquim da; Furusho,Alethéia dos Santos; Miguel,Obdulio Gomes; Dias,Josiane de Fatima Gaspari; Zanin,Sandra Maria Warumby; Miguel,Marilis Dallarmi. |
| Myrcia hatschbachii D. Legrand (Myrtaceae) is a native and endemic species from Brazil. This study investigated the essential oil composition, phytotoxic potential, in vitro toxicity, antioxidant properties and antibacterial activity of species. Chromatographic analysis of essential oil identified trans-calamanene, (E)-caryophyllene and spathulenol as major components. Antioxidant capacity was determined by the DPPH• scavenging method and phosphomolybdenum complex formation assay. Antibacterial activity was evaluated using the Minimal Inhibitory Concentration test, demonstrating that the essential oil was active toward Enterococcus faecalis and Staphylococcus aureus. Phytotoxic activity of essential oil was analyzed by testing interference on germination... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Essential oil; Phytotoxic; Antioxidant; Antibacterial; Hemolysis; Artemia salina. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100560 |
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| Cansian,Fernanda Colombi; Merino,Francis José Zortéa; Dias,Josiane de Fátima Gaspari; Zanin,Sandra Maria Warumby; Miguel,Obdulio Gomes; Miguel,Marilis Dallarmi. |
| Species from the Bignoniaceae Family, including the genus Tynanthus, are very prevalent in the tropical Americas, with specimens found in a large part of the Brazilian territory. These plants are commonly used in traditional medicine for several purposes, and some studies have described their chemical structure, in addition to other reports related to some species from this genus. This review aimed to gather information from published works concerning species of the genus Tynanthus, as well as to detect flaws in research related to these plants, which may have great biological and pharmaceutical importance. Also, this review points out some common chemical characteristics of these species, providing information that may help new researchers to improve... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tynanthus/pharmacognosy; Tynanthus/phytochemistry; Tynanthus/biological activity; Bignoniaceae/pharmacognosy; Bignoniaceae/phytochemistry; Medicinal plants. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300515 |
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| Fabri,Natasha Tiemi; Gatto,Larissa Junqueira; Furusho,Alethéia Santos; Garcia,Meira Janette Ballestros; Marques,Francisco de Assis; Miguel,Marilis Dallarmi; Montrucchio,Deise Prehs; Zanin,Sandra Maria Warumby; Miguel,Obdulio Gomes; Dias,Josiane de Fátima Gaspari. |
| The article has aimed to characterize the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. leaves, in terms of its chemical composition and antioxidant, hemolytic, and phytotoxic potentials, as well as its toxicity against Artemia salina. The major constituents identified by CG-MS were d-elemene, spathulenol, and b-atlantol. When screened for potential biological activities, the essential oil presented low toxicity against Artemia salina, and a capacity of lysing red blood cells. Also, the evaluation of its in vitro antioxidant activity, using the phosphomolybdenum method, showed better results when compared to butylhydroxytoluene (BHT) and rutin. In conclusion, the results obtained showed certain in vitro toxicity, leading to an interesting... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ocotea diospyrifolia; Lauraceae; Spathulenol; Antioxidant; Toxicity. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100593 |
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| Betim,Fernando Cesar Martins; Oliveira,Camila Freitas de; Souza,Angela Maria de; Szabo,Ellis Marina; Zanin,Sandra Maria Warumby; Miguel,Obdulio Gomes; Miguel,Marilis Dallarmi; Dias,Josiane de Fátima Gaspari. |
| The present study was undertaken to assess the potential uses of the essential oil obtained from Ocotea nutans (Nees) Mez. The hydrodistilled essential oil from O. nutans leaves was analyzed by gas chromatography-mass spectrometry. Fifty-eight compounds representing 87,29% of the total leaf essential oil components were identified, of which biciclogermacrene(11.41%), germacrene-D (4.89%), bisabolol-11-ol(3.73%) and spathulenol (3.71%) were the major compounds. The essential oil from O. nutans were tested for antibacterial activity using the minimum inhibitory concentracion (MIC) method, Artemia salina method, larvicidal activity in Aedes aegypti, and antioxidant capacity.The antioxidant activity measured by the phosphomolybdenum complex and Prussian blue... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ocoteanutans/essential oil/evaluation; Antioxidant capacity; Aedesaegypti; Toxic potential. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100513 |
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| Oliveira,Camila Freitas de; Oliveira,Vinicius Bednarczuk; Bobek,Vanessa Barbosa; Rech,Katlin Suellen; Betim,Fernando Cesar Martins; Dias,Josiane de Fatima Gaspari; Zanin,Sandra Maria Warumby; Miguel,Obdulio Gomes; Miguel,Marilis Dallarmi. |
| Psychotria fractistipula L.B.Sm, R.M. Klein & Delprete (Rubiaceae) is found in the existing Atlantic Forest in the South of Brazil, in the Paraná and Santa Catarina States. The members of Rubiaceae are characterized chemically by the presence of alkaloids, some pharmacological properties of which include antifungal, antibacterial, analgesic, antioxidant, antimutagenic, and antiviral activities. In this study, we report the results of anatomical, morphological, and histochemical analyses of the leaves and stems of the Rubiaceae family member, P. fractistipula. The anatomical analysis involved of light microscopy and scanning electron microscopy. Morpho-anatomical and histochemical characterization were made using standard methodology. The isolated... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Psychotria; Morpho-anatomical; Phytochemistry. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100565 |
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| Kalegari,Milena; Miguel,Marilis Dallarmi; Dias,Josiane de Fátima Gaspari; Lordello,Ana Luísa Lacava; Lima,Cristina Peitz de; Miyazaki,Cristina Mayumi Sasaki; Zanin,Sandra Maria Warumby; Verdam,Maria Christina dos Santos; Miguel,Obdulio Gomes. |
| Most active plants are toxic at high doses and it is therefore important to investigate the preliminary toxicity of plant extracts. The Rourea induta species is a potential drug with no phytochemical or biological studies registered in the literature. Thus, a phytochemical study and a toxicity analysis of the ethanolic extract obtained from the leaves of Rourea induta Planch., Connaraceae, was run. A long chain hydrocarbon, n-tetracosane, and four flavonoids were identified: quercetin, and three glycosylated derivates, quercetin-3-O-α-arabinofuranoside, quercetin-3-O-β-xyloside and quercetin-3-O-β-galactoside. This is the first time these have been isolated in this species. The structures were elucidated by 13C NMR, ¹H NMR, UV and IR spectroscopy. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rourea induta/phytochemistry; Connaraceae/phytochemistry; Flavonoids; N-tetracosane; Plant extracts/toxicity. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300023 |
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| Fujiwara,Gislene Mari; Campos,Ranieri; Costa,Camila Klocker; Dias,Josiane de Fátima Gaspari; Miguel,Obdulio Gomes; Miguel,Marilis Dallarmi; Marques,Francisco de Assis; Zanin,Sandra Maria Warumby. |
| Stigmasterol - a plant sterol with several pharmacological activities - is susceptible to oxidation when exposed to air, a process enhanced by heat and humidity. In this context, microencapsulation is a way of preventing oxidation, allowing stigmasterol to be incorporated into various pharmaceutical forms while increasing its absorption. Microparticles were obtained using a blend of polymers of sodium alginate, starch and chitosan as the coating material through a one-stage process using the external gelation technique. Resultant microparticles were spherical, averaging 1.4 mm in size. Encapsulation efficiency was 90.42% and method yield 94.87%. The amount of stigmasterol in the oil recovered from microparticles was 9.97 mg/g. This technique proved... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Stigmasterol/microencapsulation; Microencapsulation; Sodium alginate/drugs coating; Chitosan/drugs coating; Starch/drugs coating; Natural polymers/drugs coating. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000300015 |
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| Nunes,Patrícia Mayra Pavan; Silva,Cristiane Bezerra da; Paula,Cristiane da Silva; Smolarek,Fernanda Ferreira; Zeviani,Walmes Marques; Chaves,Suelen Cristina; Lorini,Fernando; Dias,Josiane de Fátima Gaspari; Miguel,Obdulio Gomes; Zanin,Sandra Maria Warumby; Miguel,Marilis Dallarmi. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: <; Italic>; Citrus sinensis<; /italic>; (L.) Osbeck/residues/utilization <; Italic>; Citrus sinensis<; /italic>; (L.) Osbeck/seeds/allelopathic potential Rutaceae/residues/utilization Fixed oil Fatty acid. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000200479 |
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