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Registros recuperados: 3
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AmpC beta lactamases among Gram negative clinical isolates from a tertiary hospital, South India BJM
Mohamudha,Parveen R.; Harish,B.N.; Parija,S.C..
AmpC β-lactamases are cephalosporinases that hydrolyze cephamycins as well as other extended-spectrum cephalosporins and are poorly inhibited by clavulanic acid. Although reported with increasing frequency, the true rate of occurrence of AmpC β-lactamases in different organisms, including members of Enterobacteriaceae, remains unknown. The present study was designed to determine the occurrence of AmpC enzyme-harbouring Gram-negative clinical isolates in a tertiary care hospital in Pondicherry state, South India. A total of 235 Gram negative clinical isolates were tested for resistance to cefoxitin, third generation cephalosporin (3GC) antibiotics, ampicillin, amikacin, co-trimoxazole, gentamicin, meropenem and tetracycline by disc diffusion method....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Gram negative organisms; Drug resistance; Three-dimensional technique; AmpC β-lactamases.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000300009
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Detection of multi drug resistant bacteria in major hospitals in Kano, North-West, Nigeria BJM
Yusuf,I.; Arzai,A.H.; Haruna,M.; Sharif,A.A.; Getso,M.I..
Two major hospitals in Kano, North West Nigeria have recorded increasing resistance of clinical pathogens to broad spectrum β lactams, mediated by extended spectrum β- lactamase (ESβL) and non ESBLs. A study was therefore undertaken to determine the occurrence and prevalence of plasmid and chromosomal mediated AmpC βL and carbapenemase in addition to already known ESBL due to increasing resistance of pathogens from the two hospitals to carbapenems, cephamycins and flouroquinolones. Antibiogram tests and ESBL, AmpC and carbapenemase production tests were performed on all the isolates. AmpC and carbapenemase producers were further screened for AmpC inducibility and metallo beta lactamase production respectively. Majority of the isolates (> 80%) were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: AmpC β-lactamases; Extended spectrum β-lactamases; Coexistence; Prevalence; Gram negative bacteria.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300005
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Molecular characterization and epidemiology of cefoxitin resistance among Enterobacteriaceae lacking inducible chromosomal ampC genes from hospitalized and non-hospitalized patients in Algeria: description of new sequence type in Klebsiella pneumoniae isolates BJID
Gharout-Sait,Alima; Touati,Abdelaziz; Guillard,Thomas; Brasme,Lucien; Champs,Christophe de.
In this study, 922 consecutive non-duplicate clinical isolates of Enterobacteriaceae obtained from hospitalized and non-hospitalized patients at Bejaia, Algeria were analyzed for AmpC-type β-lactamases production. The ampC genes and their genetic environment were characterized using polymerase chain reaction (PCR) and sequencing. Plasmid incompatibility groups were determined by using PCR-based replicon typing. Phylogenetic grouping and multilocus sequence typing were determined for molecular typing of the plasmid-mediated AmpC (pAmpC) isolates.Of the isolates, 15 (1.6%) were identified as AmpC producers including 14 CMY-4- producing isolates and one DHA-1-producing Klebsiella pneumoniae . All AmpC-producing isolates co-expressed the broad-spectrum TEM-1...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Enterobacteriaceae; AmpC β-lactamases; Genotyping; Algeria.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000200187
Registros recuperados: 3
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