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	Provedor de dados BJID (28) BJMBR (6) Anais da ABC (AABC) (1) J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor Brites,Carlos (5) Bonolo,P.F. (2) Diaz,Ricardo Sobhie (2) Leite,José Carlos de Carvalho (2) Luz,Estela (2) Martins Netto,Eduardo (2) Matos,Vanessa Terezinha Gubert de (2) Silveira,Vera Lúcia da (2) Abreu,Thalita F. (1) Acurcio,F.A. (1) Acurcio,Francisco A. (1) Albuquerque,M.F.P.M. (1) Albuquerque,Maria de Fatima Pessoa Militão de (1) Albuquerque,Valeria Maria Gonçalves de (1) Alves,Carmosina R. (1) Amaral,Josefina Cláudia Zirpoli (1) Andrade,Ana Cristina O. (1) Angelis,Daniela Souza Araújo de (1) Araújo,F.S. (1) Arruda Junior,Evanizio Roque de (1) Mais... Palavra-chave Antiretroviral therapy (36) HIV (14) Brazil (6) Adherence (5) AIDS (4) HIV/AIDS (4) Children (3) Efavirenz (3) HIV-1 (3) Zidovudine (3) Acquired immunodeficiency syndrome (2) HIV infection (2) Highly active (2) Human immunodeficiency virus (2) Tuberculosis (2) Vertical transmission (2) Viral load (2) AIDS/morbidity (1) AIDS/mortality (1) Adverse events (1) Mais... Tipo do documento Info:eu-repo/semantics/article (32) Info:eu-repo/semantics/other (3) Info:eu-repo/semantics/report (1) Ano 2020 (1) 2019 (1) 2018 (3) 2017 (2) 2016 (3) 2014 (1) 2012 (1) 2011 (3) 2010 (1) 2009 (1) 2008 (4) 2007 (4) 2006 (4) 2005 (1) 2004 (1) 2003 (2) 2002 (3) Mais... País Brazil (36) Idioma Inglês (36)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 36 Primeira ... 1 2 ... Última Adherence to antiretroviral therapy of Brazilian HIV-infected children and their caregivers BJID Ricci,Gabriela; Netto,Eduardo Martins; Luz,Estela; Rodamilans,Cynthia; Brites,Carlos. Abstract Background Successful treatment of HIV-positive children requires a high level of adherence (at least 95%) to highly active antiretroviral therapy. Adherence is influenced by factors related to the child and caregivers. Objectives To evaluate children and caregivers characteristics associated to children's adherence. Methods Cross-sectional study, from September 2013 to June 2015, comprising a sample of caregivers of perinatally HIV-infected children, in the age group of 1–12 years, under antiretroviral therapy for at least 6 months and on follow-up in two AIDS reference centers in Salvador, Bahia. Caregiver self-reports were the sole source of 4 days adherence and sociodemographic information. Study participants who reported an intake >95%... Tipo: Info:eu-repo/semantics/article Palavras-chave: Adherence; Antiretroviral therapy; Children; Caregivers. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500429 Aerobic capacity and health-related quality of life in adults HIV-infected patients with and without lipodystrophy BJID Gomes Neto,Mansueto; Conceição,Cristiano Sena; Ogalha,Cecília; Brites,Carlos. Abstract Introduction HIV infection and its therapy which can affect their aerobic capacity and health-related quality of life of patients. Objective We conducted a cross-sectional study to determine if aerobic capacity and health related quality of life was decreased in HIV-infected patients receiving highly active antiretroviral therapy and comparing patients with and without lipodystrophy. Research design and methods HIV-infected patients older than 18 years, and in current use of highly active antiretroviral therapy drugs, were evaluated for blood count, fasting total cholesterol, high density lipoprotein, triglycerides, glucose, HIV viral load and CD4/CD8 counts, body composition, peak oxygen consumption (peak VO2) and metabolic equivalent. Health... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antiretroviral therapy; HIV infection; Quality of life; Disability. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000100076 An adherence trilogy is essential for long-term HAART success BJID Garcia,Rosa; Schooley,Robert T.; Badaró,Roberto. Adherence is the milestone of a successful therapy. Over the last decade several authors have addressed the importance of adherence for optimal results of antiretroviral (ARV) therapy. Many health care systems are investing substantial resources to make available contemporary antiretroviral therapy. Despite the large investment in medications, insufficient investments have been made into an integrated adherence component to maximize the impact of these medications. Adherence, unlike drug therapy, cannot be defined as a single method with a defined prescription or formula. Instead, it is the result of a complex interaction between the patient, a prescribed medication and the health system. Many reports are available analyzing each of these components. We... Tipo: Info:eu-repo/semantics/article Palavras-chave: Adherence; Compliance; Antiretroviral therapy. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000500005 Antiretroviral therapy-associated dyslipidemia in patients from a reference center in Brazil BJMBR Ceccato,M.G.B.; Bonolo,P.F.; Souza Neto,A.I.; Araújo,F.S.; Freitas,M.I.F.. The aim of this study was to determine the impact of antiretroviral therapy on the lipid profile of human immunodeficiency virus (HIV) patients before and after the initiation of highly active antiretroviral therapy (HAART). This was a cross-sectional analysis of patients receiving HAART at a reference center in Belo Horizonte, Brazil, on the basis of medical records from 2002 to 2006. Patients were included if they had at least one lipid test or a clinical or laboratory diagnosis of dyslipidemia/lipodystrophy. Among the 692 patients, 620 met the eligibility criteria. The majority were males (66.5%), middle age (average 39 years), had a low educational level (60.4%), and low income (51.0%). HAART duration ranged from 11 days to 4.6 years, with a mean of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antiretroviral therapy; Dyslipidemia; Lipodystrophy; Management. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001100015 Characteristics of HIV antiretroviral regimen and treatment adherence BJID Silveira,Vera Lúcia da; Drachler,Maria de Lourdes; Leite,José Carlos de Carvalho; Pinheiro,Cézar Arthur Tavares. The relationship between characteristics of HIV antiretroviral regimens and treatment adherence was studied in adolescent and adult patients who underwent antiretroviral therapy from January 1998 to September 2000, at the Service for Specialized Assistance in Pelotas. The patients were interviewed on two occasions, and the use of antiretrovirals during the previous 48 hours was investigated by a self-report. Adherence was defined as use of 95% or more of the prescribed medication. Social-demographic variables were collected through direct questionnaires. The antiretroviral regimen and clinical data were copied from the patients' records. Associations between the independent variables and adherence were analyzed by means of logistic regression. The... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV/AIDS; Adherence; Antiretroviral therapy. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300004 Characterization of virologic failure after an initially successful 48-week course of antiretroviral therapy in HIV/AIDS outpatients treated in Santos, Brazil BJID Caseiro,Marcos M.; Golegã,Alcino A.C.; Etzel,Arnaldo; Diaz,Ricardo Sobhie. We characterized the virologic failure after an initially successful 48-week course of antiretroviral therapy among HIV/AIDS patients in a retrospective cohort study involving patients from Santos, Brazil. Patients with plasma HIV RNA below 500 copies/mL for 48 weeks were included. Variables analyzed included gender, age, level of education, marital status, mode of HIV acquisition, viral load, and CD4 cell count upon admission. There were 4,909 patients registered with the clinic, of which 669 patients met all the inclusion criteria (41.6% female and 58.4% male). Only 27.5% of the patients maintained undetectable viral loads during up to one year of follow-up. After 48 weeks, virologic failure occurred earlier in females and in patients first treated with... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antiretroviral therapy; Virologic failure; HIV; Brazil. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300001 CYP2B6 516 G&gt;T polymorphism and side effects of the central nervous system in HIV-positive individuals under Efavirenz treatment: Study of a sample from southern Brazil Anais da ABC (AABC) MÜLLER,TALISE E.; ELLWANGER,JOEL H.; MICHITA,RAFAEL T.; MATTE,MARIA CRISTINA C.; RENNER,JANE D.P.. ABSTRACT This study aimed to identify the 516 G>T polymorphism of the CYP2B6 gene and evaluate its influence on central nervous system (CNS) side effect development in HIV-positive individuals undergoing Efavirenz (EFV) treatment in a population from southern Brazil. Additionally, we performed a survey on the clinical and epidemiological characteristics of our sample. In addition to medical records evaluation, whole blood of 89 individuals was analyzed for viral load, T lymphocyte count (CD4+ and CD8+), and the polymorphism. Considering the side effects of the CNS reported by individuals but without considering the genetic variables, no statistically significant association was noted between the adverse effects and the antiretroviral treatment... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; Efavirenz; Antiretroviral therapy; CYP2B6. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000200497 Different nutritional-state indicators of HIV-positive individuals undergoing antiretroviral therapy J. Venom. Anim. Toxins incl. Trop. Dis. Geraix,J.; Carvalhaes,M. A. B. L.; Pereira,P. C. M.. This study aimed at learning about the nutritional profile of HIV-positive individuals undergoing antiretroviral therapy and at comparing the performance of nutritional-state indicators. A transversal study was performed on 94 patients attending the Tropical Diseases Outpatient Hospital of Botucatu Medical School (FMB) - UNESP. The body mass index (BMI) and the classification by Papini-Berto (PB) were used to evaluate nutritional state, aiming at detecting malnutrition and obesity. The waist-to-hips ratio (W/HR) and waist circumference (WC) were adopted for identification of abdominal obesity and lipodystrophy. According to BMI, most of the individuals were eutrophic, followed by 30.9% overweight and 6.4% malnourished. By using the PB classification, the... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; AIDS; Antiretroviral therapy; Nutritional indicators. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000200011 Efficacy and safety of Efavirenz in HIV patients on Rifampin for tuberculosis BJID Pedral-Sampaio,Diana B.; Alves,Carmosina R.; Netto,Eduardo M.; Brites,Carlos; Oliveira,Adriano S.; Badaro,Roberto. Forty-nine AIDS patients, most of who were antiretroviral therapy (ARV) naïve, with active tuberculosis, were treated with Rifampin 600mg, Isoniazid 400mg and Pirazinamide 2g daily. They also received ARV, consisting of Efavirenz (600mg/day) plus 2 NRTIs. All patients were prospectively followed for at least 24 months. Baselines were: male/female ratio 2:1, mean age 34.7 ± 9.4 yrs; weight 51 ± 9.0 kg, viral load 5.6 ± 0.6 logs, CD4 cell count 101 ± 128 cells/ mm³. Follow up mean values of data logs of VL and CD4+ cell /mm³ counts were: VL 1.7 and CD4+ 265; VL 1.3 and CD4+ 251; VL 1.4 and CD4+ 326 at 6, 12 and 24 months, respectively. Weight gain changes were: 5 ± 9.9 ± 12 and 21 ± 16 kg respectively at 6, 12 and 24 months. A non-concomitant ARV regimen was... Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; HIV/AIDS; Drug interaction; Rifampin; Efavirenz; Antiretroviral therapy. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000300004 Endothelial function and cardiovascular diseases in HIV infected patient BJID Andrade,Ana Cristina O.; Cotter,Bruno R.. The HIV epidemic has dramatically changed the paradigm for the development of drug therapy in the last 15 years. The goal is now not only to provide an effective reduction of plasma viremia , but also to reconstitute the immune deficiency due to the progression of the disease. Significant problems with the metabolism of sugars and lipids lead to the appearance of well-documented disorders such as insulin resistance, abnormalities in lipid metabolism and lipodystrophy in those patients on prolonged therapy with antiretrovirals. The question of whether or not HAART-associated lipid disorders contribute to the premature development of coronary artery disease is of major importance for the HIV community. Endothelial injury is associated with disease-related... Tipo: Info:eu-repo/semantics/article Palavras-chave: Human immunodeficiency virus; Endothelial dysfunction; Endothelial adhesion molecules; Antiretroviral therapy; Cardiovascular risk factors; Atherosclerosis; Coronary heart disease. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000200012 Enteric parasitic infections in HIV/AIDS patients before and after the highly active antiretroviral therapy BJID Bachur,Tatiana Paschoalette Rodrigues; Vale,Josias Martins; Coêlho,Ivo Castelo Branco; Queiroz,Telma Régia Bezerra Sales de; Chaves,Cristina de Souza. Enteroparasites are related to gastrointestinal alterations among patients with HIV/AIDS, some causing severe manifestations in the period before the institution of the highly active antiretroviral therapy (HAART). The prevalence of enteroparasitoses in patients with HIV/AIDS seen at two hospitals in Ceará , Brazil, was compared in the pre-HAART (Group 1; n = 482) and HAART (Group 2; n = 100) eras. Fecal parasitologic examinations (FPE) were performed using the direct, Lutz, Baermann-Moraes and modified Ziehl-Neelsen methods. The following parasites were detected in Groups 1 and 2, respectively: Strongyloides stercoralis - 30.1% and 11% (p<0.0001), Ascaris lumbricoides - 15.6% and 2% (p<0.0001), hookworms - 13.7% and 2% (p<0.0001), Trichuris... Tipo: Info:eu-repo/semantics/article Palavras-chave: Enteric parasitic infections; HIV; AIDS; Antiretroviral therapy. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000200004 Estimating the length of the first antiretroviral therapy regiment durability in São Paulo, Brazil BJID Medeiros,Roseane; Diaz,Ricardo S.; Castelo Filho,Adauto. Brazil was the first country to provide unrestricted, cost-free access to antiretroviral (ARV) medicine for AIDS treatment. However, there is little data about the benefits of such a policy for these patients. We evaluated the duration of benefit obtained with the introduction of ARVs, defined as the durability of the first ARV regiment. We reviewed the medical charts of patients attended from 1996-2000, at the outpatient clinics of the Federal University of São Paulo, Brazil. A total of 120 drug-naive HIV-1 infected patients were eligible to participate in the study. About half of the individuals (53%) presented with disease symptoms; 59% of them had CD4 count below 200 cells/mm³. Mean estimated duration of the benefit of therapy was 14.1 months. The most... Tipo: Info:eu-repo/semantics/article Palavras-chave: Zidovudine; Antiretroviral therapy; São Paulo; Brazil. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600005 Evaluation of genotype resistance testing for salvage antiretroviral therapy at AIDS care centers from Ribeirão Preto, São Paulo, Brazil BJMBR Pires Neto,R.J.; Colares,J.K.B.; Fonseca,B.A.L.. The availability of HIV-1 genotype resistance testing (GRT) to clinicians has been insufficiently studied outside randomized clinical trials. The present study evaluated the outcome of salvage antiretroviral therapy (ART) recommended by an expert physician based on GRT in a non-clinical trial setting in Ribeirão Preto, Brazil. A prospective, open, nonrandomized study evaluating easy access to GRT at six Brazilian AIDS Clinics was carried out. This cooperative study analyzed the efficacy of treatment recommended to patients whose salvage ART was guided by GRT with that of treatment with ART based only on previous ART history. A total of 112 patients with ART failure were included in the study, and 77 of them were submitted to GRT. The median CD4 cell count... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV-1; Antiretroviral therapy; Salvage therapy; HIV-1 genotype resistance testing. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000600016 Factors associated to modification of first-line antiretroviral therapy due to adverse events in people living with HIV/AIDS BJID Azevedo,Larissa Negromonte; Ximenes,Ricardo Arraes de Alencar; Monteiro,Polyana; Montarroyos,Ulisses Ramos; Miranda-Filho,Demócrito de Barros. ABSTRACT Antiretroviral therapy (ART) has modified the outcome of patients with HIV infection, providing virological control and reducing mortality. However, there are several reasons as to why patients may discontinue their antiretroviral therapy, with adverse events being one of the main reasons reported in the literature. This is a case-control nested in a cohort of people living with HIV/AIDS, conducted to identify the incidence of ART modification due to adverse events and the associated factors, in two referral services in Recife, Brazil, between 2011 and 2014. Of the modifications occurred in the first year of ART, 25.7% were driven by adverse events. The median time elapsed between initiating ART and the first modification due to adverse events was... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antiretroviral therapy; Zidovudine; Tenofovir; Efavirenz; Adverse events. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000100065 Factors associated with adherence to antiretroviral therapy in HIV/AIDS patients: a cross-sectional study in Southern Brazil BJMBR Pinheiro,C.A.T.; de-Carvalho-Leite,J.C.; Drachler,M.L.; Silveira,V.L.. A cross-sectional study was conducted on HIV-infected adults being treated with antiretroviral drugs at a reference service in Southern Brazil. Participants answered a sociodemographic questionnaire and were tested by scales assessing sociocognitive variables. Adherence to treatment was assessed by a self-report inventory developed for the study. Clinical information was obtained from the patients' records. Significance tests were conducted using univariate logistic regressions followed by multivariate logistic regression analysis. A total of 195 patients participated in the study and 56.9% of them reported > or = 95% adherence on the previous two days. In univariate analysis, the odds of adherence increased with self-efficacy (a person's conviction... Tipo: Info:eu-repo/semantics/article Palavras-chave: Adherence; Antiretroviral therapy; Self-efficacy; HIV; AIDS. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001000010 High incidence of adverse reactions to initial antiretroviral therapy in Brazil BJMBR Menezes de Pádua,C.A.; César,C.C.; Bonolo,P.F.; Acurcio,F.A.; Guimarães,M.D.C.. A concurrent prospective study was conducted from 2001 to 2003 to assess factors associated with adverse reactions among individuals initiating antiretroviral therapy at two public referral HIV/AIDS centers in Belo Horizonte, MG, Brazil. Adverse reactions were obtained from medical charts reviewed up to 12 months after the first antiretroviral prescription. Cox proportional hazard model was used to perform univariate and multivariate analyses. Relative hazards (RH) were estimated with 95% confidence intervals (CI). Among 397 charts reviewed, 377 (95.0%) had precise information on adverse reactions and initial antiretroviral treatment. Most patients received triple combination regimens including nucleoside reverse transcriptase inhibitors, non-nucleoside... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antiretroviral therapy; Adverse reactions to antiretroviral therapy; Medical records. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000400010 High vertical HIV transmission rate in the Midwest region of Brazil BJID Matos,Vanessa Terezinha Gubert de; Batista,Fabiani de Morais; Versage,Naiara Valera; Pinto,Clarice Souza; Oliveira,Vanessa Marcon de; Vasconcelos-Pereira,Érica Freire de; Matos,Roberta Barbeta dos Rios de; Fabbro,Márcia Maria Ferrairo Janini Dal; Oliveira,Ana Lúcia Lyrio de. ABSTRACT Objectives To estimate vertical HIV transmission rate in a capital city of the Midwest region of Brazil and describe the factors related to transmission. Methods A descriptive epidemiological study based on the analysis of secondary data from the Notifiable Diseases Information System (SINAN). The analysis considered all HIV-infected pregnant women with delivery in Campo Grande-MS in the years 2007-2013 and their HIV-exposed infants. Results A total of 218 births of 176 HIV-infected pregnant women were identified during the study period, of which 187 infants were exposed and uninfected, 19 seroconverted, and 12 were still inconclusive in July 2015. Therefore, the overall vertical HIV transmission rate in the period was 8.7%. Most (71.6%) of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Vertical transmission; HIV; Disease prevention; Antiretroviral therapy; Prenatal follow-up; Health services; Social environment. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000300177 HIV-1 drug resistance genotypic profiles in children with undetectable plasma viremia during antiretroviral therapy BJID Angelis,Daniela Souza Araújo de; Tateno,Adriana Fumie; Diaz,Ricardo Sobhie; Succi,Regina Célia de Menezes; Pannuti,Claudio Sergio; Gouvea,Aida de Fátima Barbosa; Machado,Daisy Maria. Treatment of HIV-1 infection with highly active antiretroviral therapy has led to sustained viral suppression in the plasma in a large number of children. However, studies have suggested that the integrated provirus in resting CD4+ T lymphocytes could be a source of reactivatable virus and maintain drug-resistant virus. We evaluated the resistance-related mutations in children receiving antiretroviral therapy with prolonged viral suppression. Thirty-two peripheral blood mononuclear cell samples from 16 children with viral loads that had been below detection limits for at least 12 months were obtained at two different time points and the DNAs sequenced. The median CD4 cell count was 1,016 cells/mm³ (347-2,588) and 938 cells/mm³ (440-3,038) at the first and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Children; HIV-1; Prolonged viral suppression; Antiretroviral therapy; Antiretroviral resistance. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000100011 HIV-1 viremia during the first 28 weeks of pregnancy is not associated with mother-to-child transmission BJID Senise,J.F.; Palacios,R.; Tanno,Z.N.; Lunardi,L.; Waghabi,G.R.; Vaz,M.J.R.; Diaz,RS.; Castelo,A.. It is currently recommended that antiretroviral prophylaxis to prevent mother-to-child transmission (MTCT) of HIV be initiated at 14 weeks of gestation. However, the relevance of early-gestation HIV viral load level for intrauterine MTCT is unknown. The objective of this study was to determine the relationship between prenatal maternal viral load and intrauterine MTCT. Records of HIV-infected pregnant women in two centers in Brazil, from 1999 to 2004 were analyzed. Three pregnancy periods were considered: earlier than 14 weeks, 14 to 27 6/7 weeks, and 28 weeks of gestation or more. Peripartum HIV exposure was also computed. Maximum viral load in each period was the measure of HIV exposure. Four hundred fifty-seven HIV-infected pregnant women were... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV-1; Disease transmission; Vertical transmission; Antiretroviral therapy; Highly active; Brazil; Viral load. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400009 HIV/AIDS treatment and physicochemical quality control of medicines: evaluation of non-generic lamivudine + zidovudine tablets manufactured in Brazil BJID Beck,Ruy Carlos Ruver; Athayde,Margareth Linde; Cardoso,Simone Gonçalves. In this work it was evaluated the physicochemical quality of lamivudine + zidovudine tablets, whose association belongs to the list of drugs distributed by the Brazil's National Program on Sexually Transmitted Diseases and AIDS. Four non-generic products (lamivudine + zidovudine tablets) were analyzed. They were obtained from different Brazilian manufacturers, besides a reference product. The quality was evaluated by physicochemical tests described in the official codes. A validated reversed-phase high performance liquid chromatography (HPLC) method was used for the assay of the active substances. All samples were in accordance to the requisites in relation to their physicochemical characteristics. Dissolution studies showed similar drug percentual... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antiretroviral therapy; Quality control; Lamivudine; Public health; Tablets; Zidovudine. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000600003 Registros recuperados: 36 Primeira ... 1 2 ... Última

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