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Autologous transplant: microbial contamination of hematopoietic stem cell products BJID
Almeida,Igor Dullius; Schmalfuss,Tissiana; Röhsig,Liane Marise; Goldani,Luciano Zubaran.
Hematopoietic progenitor cells from peripheral blood (HPCPB) are commonly used for autologous and allogenic transplants in patients with most various onco-hematological diseases, and despite the utilization of sterile techniques during collection and processing of these products, bacterial contamination can occur. This study aimed to investigate the microbial contamination of HPCPB products. Microbial cultures of 837 HPCPB products between the year 2000 and 2009 were retrospectively analyzed to determine the incidence of culture positivity and identify the main organisms that cause contamination. The microbiological studies were performed with an automated system (BacT/Alert® bioMérieux Corporate). Thirty-six (4.3%) of 837 microbial cultures were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Autologous transplant; Hematopoietic stem cell products; Microbial contamination; Quality control; Bacterial contamination.
Ano: 2012 URL:
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