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Arachidonic acid affects biofilm formation and PGE2 level in Candida albicans and non-albicans species in presence of subinhibitory concentration of fluconazole and terbinafine BJID
Mishra,Nripendra Nath; Ali,Shakir; Shukla,Praveen K..
Candida albicans utilizes arachidonic acid (AA) released during the course of infection (Candidiasis) from phospholipids of infected host cell membranes and synthesizes extracellular prostaglandin(s) which play an important role in hyphae formation and host cell damage. C. albicans biofilms secrete significantly more prostaglandin(s) and evidence suggests that Candida biofilms have dramatically reduced susceptibility to majority of antifungal drugs. AA influences the saturation level of lipids and fluidity of yeast cell membranes. Therefore the aim of this study was to evaluate the effect of AA alone or in combination with antifungal agents on biofilm formation and production of prostaglandin (PGE2) in C. albicans, C. parapsilosis, C. glabrata, C....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Arachidonic acid; Candida albicans; AmBR; Candida tropicalis; Prostaglandin E2; FDA.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000300287
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Biochemical characterization of a Kunitz inhibitor from Inga edulis seeds with antifungal activity against Candida spp. Repositório Alice
DIB, H. X.; OLIVEIRA, D. G. L. de; OLIVEIRA, C. F. R. de; TAVEIRA, G. B.; MELLO, E. de O.; VERBISCK, N. V.; CHANG, M. R.; CORRÊA JUNIOR, D.; GOMES, V. M.; MACEDO, M. L. R..
We describe the characterization of IETI, the first trypsin inhibitor purified from Inga edulis, a tree widely distributed in Brazil. Two-step chromatography was used to purify IETI, a protein composed of a single peptide chain of 19,685.10 Da. Amino-terminal sequencing revealed that IETI shows homology with the Kunitz family, as substantiated by its physical?chemical features, such as its thermal (up to 70 °C) and wide-range pH stability (from 2 to 10), and the value of its dissociation constant (6.2 nM). IETI contains a single reactive site for trypsin, maintained by a disulfide bridge; in the presence of DTT, its inhibitory activity was reduced in a time- and concentration-dependent manner. IETI presented activity against Candida ssp., including C....
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Candida buinensis; Trypsin inhibitors; Membrane permeability; Candida tropicalis.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1106185
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Biodegradation of crude petroleum oil and environmental pollutants by Candida tropicalis strain BABT
Farag,Soha; Soliman,Nadia A..
A local yeast isolate named A was isolated from polluted area of Abou-Qir gulf (Alexandria, Egypt), identified according to a partial sequence of 18sRNA as Candida tropicalis. The isolate showed a high potency in petroleum oil biodegradation as well some hydrocarbons. Morphological changes in cell diameter of this yeast were recognized upon growing the target cell in sea water medium supplemented with petroleum oil as sole carbon source in comparison to the growth in enriched medium. Statistically-based experimental design was applied to evaluate the significance of factors on petroleum oil biodegradation by this yeast isolate. Eleven culture conditions were examined by implementing Plackett-Burman factorial design where aeration, NH4Cl and K2HPO4 had the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Petroleum oil; Candida tropicalis; 18Sr RNA; Biodegradation; Plackett-Burman.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000400023
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Candiduria nosocomial: etiología y prevalencia de sus agentes causales en el Hospital Paroissien ABCL
Mónaco,Liliana Silvia; Bosio,Oscar; Bava,Amadeo Javier.
Se evaluó retrospectivamente la etiología y evolución de la frecuencia de los agentes causales de candiduria, en 300 episodios ocurridos en pacientes internados en el Hospital Paroissien, entre el 21 de enero de 2000 y el 30 de diciembre de 2009. Fueron diagnosticados 33 (11,0%) episodios en 2000, 26 (8,7%) en 2001, 34 (11,3%) en 2002, 20 (6,7%) en 2003, 30 (10,0%) en 2004, 25 (8,3%) en 2005, 47 (15,7%) en 2006, 27 (9,0%) en 2007, 33 (11,0%) en 2008 y 25 (8,3%) en 2009. Candida tropicalis, C. albicans, C. glabrata y C. parapsilosis prevalecieron en orden descendente de frecuencia y C. guillermondii, C. krusei y C. lusitaniae se aislaron excepcionalmente. C. tropicalis prevaleció entre 2000-2002, 2004-2006 y en 2008, seguida por C. albicans, que fue la más...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candiduria; Candida tropicalis; Micosis; Infección urinaria.
Ano: 2010 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-29572010000400012
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Physiological changes of Candida tropicalis population degrading phenol in fed batch reactor BABT
Komarkova,Eliska; Paca,Jan; Klapkova,Eva; Stiborova,Marie; Soccol,Carlos R; Sobotka,Miroslav.
Candida tropicalis can use phenol as the sole carbon and energy source. Experiments regarding phenol degradations from the water phase were carried out. The fermentor was operated as a fed-batch system with oxistat control. Under conditions of nutrient limitation and an excess of oxygen the respiration activity of cells was suppressed and some color metabolites (black-brown) started to be formed. An accumulation of these products inhibited the cell growth under aerobic conditions. Another impact was a decrease of the phenol hydroxylase activity as the key enzyme of the phenol degradation pathway at the end of the cell respiration activity. This decrease is linked with the above mentioned product inhibition. The cell death studied by fluorescent probe...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Phenol; Biodegradation; Candida tropicalis; Phenol hydroxylase; Starvation stress; Viability.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132003000400007
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Presence of the yeast Candida tropicalis in figs infected by the fruit fly Zaprionus indianus (dip.: Drosophilidae) BJM
Gomes,Luiz H.; Echeverrigaray,Sergio; Conti,José H.; Lourenço,Marcus Vinicius M.; Duarte,Keila M.R..
In the last years, the fruit fly Zapronius indianus became the most important plague of Brazilian fig production. A fermentation process is associated with infection of the fruit by this fly. A single yeast species, Candida tropicalis, was identified in all the infected figs. The presence of one species and the low genetic variability (RAPD) of the isolates indicates an uncommonly strict interaction between C. tropicalis and Z. indianus.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Zaprionus indianus; Candida tropicalis; RAPD markers; Yeast-insect association.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822003000100002
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Reclassification of Candida guilliermondii FTI 20037 as Candida tropicalis based on molecular phylogenetic analysis BJM
Lima,Luanne Helena Augusto; Felipe,Maria das Graças de Almeida; Torres,Fernando Araripe Gonçalves.
Yeasts of the genus Candida are of clinical importance and also have many industrial applications, mainly in the food industry. The yeast Candida guilliermondii FTI 20037 has been extensively studied in order to establish a biotechnological process for the production of xylitol. The goal of this study was to verify the taxonomic classification of this strain based on the analysis of rDNA sequences and the xyl1 gene. DNA fragments from these sequences were amplified by PCR and BLAST analysis revealed strong identity with the corresponding sequences from Candida tropicalis. Based on these results, we propose that C. guilliermondii FTI 20037 must be reclassified as C. tropicalis.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida guilliermondii; Candida tropicalis; Ribosomal DNA; Xylitol.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822003000500033
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Seleção e identificação de nova linhagem de levedura não-Saccharomyces tolerante ao hidrolisado lignocelulósico de cana-de-açúcar para produção de xilitol. Repositório Alice
MORAIS JÚNIOR, W. G. de; PACHECO, T. F.; TRICHEZ, D.; ALMEIDA, J. R. M. de; GONCALVES, S. B..
bitstream/item/184322/1/EnPI-2018-16.pdf
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Xilitol; Hidrolisado de cana-de-açúcar; Candida tropicalis.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1097342
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Septic arthritis as the first sign of Candida tropicalis fungaemia in an acute lymphoid leukemia patient BJID
Vicari,Perla; Pinheiro,Ronald Feitosa; Chauffaille,Maria de Lourdes Lopes Ferrari; Yamamoto,Mihoko; Figueiredo,Maria Stella.
Fungal infections caused by Candida species have increased in incidence during the past two decades in England, North America and Europe. Candidal arthritis is rare in patients who are not intravenous drug users or are who not using a prostheses. We report the case of a 24-year-old man with acute lymphoid leukemia, who developed Candida tropicalis arthritis during an aplastic period after chemotherapy. This is the eighth case described in the literature of C. tropicalis causing arthritis without intra-articular inoculation. We call attention to an unusual first sign of fungal infection: septic arthritis without intra-articular inoculation. However, this case differs from the other seven, since despite therapy a fast and lethal evolution was observed. We...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Septic arthritis; Candida tropicalis; Fungal infections; Candida tropicalis arthritis; Systemic candidiasis.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000600012
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Xylitol production on sugarcane biomass hydrolysate by newly identified Candida tropicalis JA2 strain. Repositório Alice
MOARAIS JUNIOR, W. G.; PACHECO, T. F.; TRICHEZ, D.; ALMEIDA, J. R. M. de; GONCALVES, S. B..
bitstream/item/207749/1/yea.3394.pdf
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Sugarcane biomass hydrolysate; Candida tropicalis; Xylitol.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1117561
Registros recuperados: 10
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