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| Paccola,Edneia A. de Souza; Maki,Cristina Sayuri; Nobrega,Gisele M.A. de; Paccola-Meirelles,Luzia Doretto. |
| Five species of edible mushrooms, Lentinula edodes, Pleurotus ostreatus, Pholiota nameko, Macrolepiota bonaerensis and Agaricus blazei, were tested for their potential to inhibit the in vitro growth of the pathogenic yeast Candida albicans. Only L. edodes had a fungistatic effect on this human pathogen. The inhibitory compound was produced intra and extracellularly in submersed L. edodes culture, and was also present in fresh and dehydrated mushroom basidiocarps. The fungistatic compound was heat sensitive and lost activity after 72 hours. |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Mushrooms; Antibiotics; Candidiasis; Fungistatic effect. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822001000300003 |
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| Colombo,Arnaldo Lopes; Guimarães,Thaís; Camargo,Luis Fernando Aranha; Richtmann,Rosana; Queiroz-Telles,Flavio de; Salles,Mauro José Costa; Cunha,Clóvis Arns da; Yasuda,Maria Aparecida Shikanai; Moretti,Maria Luiza; Nucci,Marcio. |
| Candida infections account for 80% of all fungal infections in the hospital environment, including bloodstream, urinary tract and surgical site infections. Bloodstream infections are now a major challenge for tertiary hospitals worldwide due to their high prevalence and mortality rates. The incidence of candidemia in tertiary public hospitals in Brazil is approximately 2.5 cases per 1000 hospital admissions. Due to the importance of this infection, the authors provide a review of the diversity of the genus Candida and its clinical relevance, the therapeutic options and discuss the treatment of major infections caused by Candida. Each topography is discussed with regard to epidemiological, clinical and laboratory diagnostic and therapeutic recommendations... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candidiasis; Candidemia; Treatment; Antifungals. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300001 |
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| Queiroz-Telles,Flávio; Silva,Nanci; Carvalho,Miriam M.; Alcântara,Ana Paula; Matta,Daniel da; Barberino,Maria G.; Bartczak,Sergio; Colombo,Arnaldo Lopes. |
| This study was a non-comparative multicenter clinical trial to evaluate the efficacy and tolerability of itraconazole oral solution 200 mg/day (100 mg twice a day in the fasting state) for the treatment of oropharyngeal candidiasis in AIDS patients. We included 50 patients who were treated and followed for up to 3 weeks after ending therapy in the analysis. Mycological cures at the end of therapy occurred in 20/50 patients (40%), but colonization by Candida sp. was recorded in 42/50 (84%) by the end of follow-up. A high rate of clinical response was observed in 46/50 (92%), and the response was sustained for up to 21 days after stopping therapy in 24/46 patients (52%). Clinical relapses were documented among 22 patients, but all causative fungal organisms... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: AIDS; Candidiasis; Itraconazole. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000200003 |
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| OLIVEIRA,FERNANDO A. DE; RORATO,VANESSA C.; ALMEIDA-APOLONIO,ADRIANA A.; RODRIGUES,ALLAN B.; BARROS,ALINE L. DE; SANGALLI,ANDRÉIA; ARENA,ARIELLE C.; MOTA,JONAS S.; GRISOLIA,ALEXÉIA B.; OLIVEIRA,KELLY M.P. DE. |
| ABSTRACT Myracrodruon urundeuva is a plant native to Brazil, which is used by the indigenous population for the treatment of candidiasis. The aims of this study were to evaluate the antifungal activity of extract against human vaginal Candida species and evaluate the possible toxicological activities of M. urundeuva. Initially, ethanol extracts, ethyl acetate fractions, and hydroalcoholic fractions of the bark and leaf of M. urundeuva were used to determine the minimum inhibitory concentration. The extracts that showed antifungal activity were characterized by liquid chromatography and subjected to toxicity assessment. Toxic, cytotoxic, genotoxic, and mutagenic testing were performed using Allium cepa and Ames assays with the ethanol extracts of the bark... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anacardiaceae; Candidiasis; Myracrodruon urundeuva; Traditional medicine. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000502423 |
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