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Effects of chondroitin sulfate and sodium hyaluronate on chondrocytes and extracellular matrix of articular cartilage in dogs with degenerative joint disease Arq. Bras. Med. Vet. Zootec.
Gonçalves,G.; Melo,E.G.; Gomes,M.G.; Nunes,V.A.; Rezende,C.M.F..
Samples of articular cartilage of femur, tibia and patella of 15 dogs with experimentally induced degenerative joint disease (DJD) were microscopically analyzed. Animals were distributed into three groups (n=5): the control group received no medication; the second group was treated with chondroitin sulfate and the third received sodium hyaluronate. Samples were processed and stained with HE and toluidine blue for morphological evaluation. The metabolic and proliferative activity of the chondrocytes was evaluated by the measurement of nucleolar organizer regions (NORs) after impregnation by silver nitrate. Significant differences were not observed (P>0.05) in the morphology among the groups, however, the group treated with sodium hyaluronate had a higher...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dog; Degenerative joint disease; Chondroitin sulfate; Sodium hyaluronate; NOR.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000100014
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Morgan line and its relationship with distraction index, angle of inclination and degenerative joint disease in the diagnosis of canine hip dysplasia Arq. Bras. Med. Vet. Zootec.
Miranda,F.G.; Rezende,C.M.F.; Silva,E.F.; Rocha,B.D.; Melo,M.M.; Tôrres,R.C.S..
ABSTRACT We evaluated 160 hip joint radiographs of 40 dogs of different large breeds (25 females and 15 males) from the metropolitan area of Belo Horizonte, Minas Gerais, Brazil. The radiographs of each dog were obtained at two different stages: stage 1 (mean 7.23 months) and stage 2 (mean 14.25). The conventional radiographic method (CRM) and the radiographic distraction method (RDM) were used, carried out in both stages. CRM measured the Norberg angle (NA), the angle of inclination (AI) and evaluated the presence of degenerative joint disease (DJD). The MRD was performed to establish the distraction index (DI). The aims were to evaluate the presence of the Morgan line and other signs of DJD and correlate them with the degree of canine hip dysplasia (CHD)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dogs; Morgan line; Hip dysplasia; Distraction index; Degenerative joint disease.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000400894
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Osteoarthritis in horses - Part 1: relationship between clinical and radiographic examination for the diagnosis BABT
Souza,Maria Verônica de.
ABSTRACT Locomotor disorders are very common in the equine clinic, which may be partly due to the different types of activities horses develop. Osteoarthritis (OA), commonly known as degenerative joint disease, presents an considerable role in the series of disorders of the musculoskeletal system and may be associated with other problems such as navicular syndrome, periostitis or osteochondrosis. This affection causes progressive deterioration of articular cartilage, accompanied by bone and soft-tissue periarticular changes. In fact, it results from a complex interaction between biochemical and biomechanical factors. The objective of this article is to review information about clinical and radiographic findings of OA, the biochemical and biomechanical...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Equine; Degenerative joint disease; Synovitis; Cartilage degeneration; Pathology of articular disease..
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100325
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Osteoarthritis in horses - Part 2: a review of the intra-articular use of corticosteroids as a method of treatment BABT
Souza,Maria Verônica de.
ABSTRACT: The problem considered in this review is related to the frequent use of corticosteroids (COs) (i.e. steroids) in the practice of equine medicine and surgery as a therapeutic strategy in the treatment of degenerative joint disease, commonly known as osteoarthritis (OA). This disease is one of the most common among the equine musculoskeletal diseases, and is clinically characterized by pain, lameness, joint effusion at the initial stage, which usually reduces with the progression of the disease, and reduced physical performance. Although steroids are considered excellent drugs in the control of clinical signs resulting from osteoarthritis, they also influence cellular activity through activation of various signaling mechanisms. However, they can...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Equine; Degenerative joint disease; Steroids; Intra-articular drugs; Treatment.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100324
Registros recuperados: 4
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