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	Provedor de dados BJMBR (2) Autor Carvalho,M.H.C. (1) David,F.L. (1) Fortes,Z.B. (1) Gattas,D. (1) Gonçalves,F.Z. (1) Lizarte Neto,F.S. (1) Lourenço,L.G. (1) Molina,C.A.F. (1) Montezano,A.C.I. (1) Nigro,D. (1) Novais,P.C. (1) Rebouças,N.A. (1) Tirapelli,D.P.C. (1) Tirapelli,L.F. (1) Tostes,R.C.A. (1) Tucci Jr,S. (1) de Carvalho,C.A.M. (1) Mais... Palavra-chave Endothelin receptors (2) Alcoholism (1) Calcium (1) Corpus cavernosum (1) DOCA-salt hypertension (1) Endothelin-1 (1) Gender (1) MiRNAs (1) Rats (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2018 (1) 2002 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Expression profile of endothelin receptors (ETA and ETB) and microRNAs-155 and -199 in the corpus cavernosum of rats submitted to chronic alcoholism and diabetes mellitus BJMBR Gonçalves,F.Z.; Lizarte Neto,F.S.; Novais,P.C.; Gattas,D.; Lourenço,L.G.; de Carvalho,C.A.M.; Tirapelli,D.P.C.; Molina,C.A.F.; Tirapelli,L.F.; Tucci Jr,S.. Recent evidence shows that chronic ethanol consumption increases endothelin (ET)-1 induced sustained contraction of trabecular smooth muscle cells of the corpora cavernosa in corpus cavernosum of rats by a mechanism that involves increased expression of ETA and ETB receptors. Our goal was to evaluate the effects of alcohol and diabetes and their relationship to miRNA-155, miRNA-199 and endothelin receptors in the corpus cavernosum and blood of rats submitted to the experimental model of diabetes mellitus and chronic alcoholism. Forty-eight male Wistar rats were divided into four groups: control (C), alcoholic (A), diabetic (D), and alcoholic-diabetic (AD). Samples of the corpus cavernosum were prepared to study the protein expression of endothelin... Tipo: Info:eu-repo/semantics/article Palavras-chave: Alcoholism; Corpus cavernosum; MiRNAs; Endothelin receptors. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000300615 Gender differences in vascular expression of endothelin and ET A/ET B receptors, but not in calcium handling mechanisms, in deoxycorticosterone acetate-salt hypertension BJMBR David,F.L.; Montezano,A.C.I.; Rebouças,N.A.; Nigro,D.; Fortes,Z.B.; Carvalho,M.H.C.; Tostes,R.C.A.. We determined if the increased vascular responsiveness to endothelin-1 (ET-1) observed in male, but not in female, DOCA-salt rats is associated with differential vascular mRNA expression of ET-1 and/or ET A/ET B receptors or with functional differences in Ca2+ handling mechanisms by vascular myocytes. Uninephrectomized male and female Wistar rats received DOCA and drinking water containing NaCl/KCl. Control rats received vehicle and tap water. Blood pressure and contractile responses of endothelium-denuded aortic rings to agents which induce Ca2+ influx and/or its release from internal stores were measured using standard procedures. Expression of mRNA for ET-1 and ET A/ET B receptors was evaluated by RT-PCR after isolation of total cell RNA from both aorta... Tipo: Info:eu-repo/semantics/article Palavras-chave: DOCA-salt hypertension; Endothelin-1; Gender; Endothelin receptors; Calcium; Rats. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000900006 Registros recuperados: 2 Primeira ... 1 ... Última

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