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APOA1/C3/A4 gene cluster variability and lipid levels in Brazilian children BJMBR
França,E. de; Alves,J.G.B.; Hutz,M.H..
Genetic studies have suggested that polymorphisms of genes coding for apolipoproteins are significant determinants of serum lipoprotein and lipid levels in adults. However, only a few studies have investigated the association of these polymorphisms in children. Therefore, in the present investigation we studied the distribution of APOA1 -75 G>A, +83 C>T, APOC3 -482 C>T, -455 T>C and 3238 C>G, and APOA4 Q360H and T347S polymorphisms and their influence on plasma lipoprotein levels in children from a Brazilian northeastern admixed population. The seven polymorphic sites were genotyped in 414 children aged 5 to 15 years (mean 8.9 ± 2.9). The genotypes of the seven polymorphic sites were assessed by PCR-RFLP methods. The frequencies of the less...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Apolipoproteins; Gene variants; Lipid levels; Children.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000400006
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Association of KCNJ11 gene variants with tenderness in Nelore breed. Repositório Alice
TIZIOTO, P. C.; SOUZA, M. M. de; MUDADU, M. de A.; THOLON, P.; MEIRELLES, S. L. C.; TULLIO, R. R.; NASSU, R. T.; ROSA, A. do N.; MEDEIROS, S. R. de; SIQUEIRA, F.; FEIJO, G. L. D.; REGITANO, L. C. de A..
The KCNJ11 (potassium inwardly-rectifying channel, subfamily J, member 11) gene is located in BTA15, near a quantitative trait loci for meat tenderness. In this study, single nucleotide polymorphisms (SNPs) were described in KCNJ11 and associated with Warner ? Bratzler shear force (WBSF) at different aging times: 1 d after slaughter (WBSF0), after 7 d (WBSF7) and 14 d (WBSF14) of aging. Fourteen steers of Nelore breed, characterized as extreme for the distribution of WBSF0 in a half-sib population of 500 progenies from 32 sires, were selected for sequencing.
Tipo: Separatas Palavras-chave: KCNJ11; Gene variants; Nelore breed; SNP.; Cattle; Meat..
Ano: 2012 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/951696
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