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| Costa,Brunna Soares Rodrigues; Freitas,Erika Paula Silva; Cruz,Marina Sampaio; Duarte,Victor Hugo Rezende; Silva,Ananília Medeiros Gomes da; Santos,Isabelle Cristina Clemente dos; Santos,Jéssica Cavalcante dos; Rezende,Adriana Augusto; Sena-Evangelista,Karine Cavalcanti Maurício; Silbiger,Vivian Nogueira. |
| ABSTRACT Chronic kidney disease (CKD) increases cardiovascular disease (CVD) risk development. However, the mechanisms of reduced kidney function with CVD risk are unclear. This study aimed to investigate the association between kidney function and Framingham risk score (FRS) in participants with traditional cardiovascular risk factors and normal estimated glomerular filtration rate (eGFR) > 60 mL/min/1.73 m² in an admixed population of Brazil. The participants were divided into three groups according to FRS: low risk group with 0% to <10%, moderate risk group with ≥10% to 20% and high risk group with >20%. The eGFR was calculated using Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). Data from participants were collected by... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chronic kidney disease; Cardiovascular diseases/risk factors; Glomerular filtration rate; Framingham risk score (FRS).. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000300626 |
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| Franco,M.C.P.; Nagasako,S.S.; Machado,P.G.; Nogueira,P.C.K.; Pestana,J.O.M.; Sesso,R.. |
| In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function. We compared GFR estimated by plasma cystatin C with GFR estimated by serum creatinine in a sample of 50 pediatric renal transplant recipients and 24 healthy children. The correlation between GFR estimated by serum creatinine and by cystatin C was significant (r = 0.75; P < 0.001, Person’s correlation); however, in pediatric kidney transplant recipients, the GFR was 6.7 mL/min lower when determined using cystatin C rather than serum creatinine. Moreover, using GFR estimated by cystatin C we found that 42% of the pediatric kidney transplant... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Children; Kidney transplant; Cystatin C; Creatinine; Glomerular filtration rate. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200017 |
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| Moehlecke,M.; Leitão,C.B.; Kramer,C.K.; Rodrigues,T.C.; Nickel,C.; Silveiro,S.P.; Gross,J.L.; Canani,L.H.. |
| The objective of this study was to evaluate the effect of metabolic syndrome (MetS) and its individual components on the renal function of patients with type 2 diabetes mellitus (DM). A cross-sectional study was performed in 842 type 2 DM patients. A clinical and laboratory evaluation, including estimated glomerular filtration rate (eGFR) calculated by the modification of diet in renal disease formula, was performed. MetS was defined according to National Cholesterol Education Program - Adult Treatment Panel III criteria. Mean patient age was 57.9 ± 10.1 years and 313 (37.2%) patients were males. MetS was detected in 662 (78.6%) patients. A progressive reduction in eGFR was observed as the number of individual MetS components increased (one: 98.2 ± 30.8;... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Metabolic syndrome; Type 2 diabetes mellitus; Glomerular filtration rate; Modification of diet in renal disease. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000700012 |
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| Silva Junior,G.B.; Libório,A.B.; Vieira,A.P.F.; Bem,A.X. Couto; Lopes Filho,A.S.; Figueiredo Filho,A.C.; Guedes,A.L.M.O.; Souza,J.H.; Costa,C.M.B.E.; Costa,R.; Daher,E.F.. |
| The objective of this study was to investigate renal function in a cohort of 98 patients with sickle cell disease (SCD) followed up at a tertiary hospital in Brazil. Clinical and laboratory characteristics at the time of the most recent medical examination were analyzed. Renal function was evaluated by the estimation of glomerular filtration rate (GFR) by the criteria of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). We compared patients with normal GFR to patients with decreased GFR (<60 mL·min-1·(1.73 m²)-1) and hyperfiltration (>120 mL·min-1·(1.73 m²)-1). Comparison between patients according to the use of hydroxyurea and comparison of clinical and laboratory parameters according to GFR were also carried out. Average patient... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Sickle cell disease; Kidney disease; Glomerular filtration rate; Creatinine; Chronic kidney disease; Hydroxyurea. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000700013 |
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| Luque,A.; Shimizu,M.H.M.; Andrade,L.; Sanches,T.R.; Seguro,A.C.. |
| Mechanical ventilation has been associated with organ failure in patients with acute respiratory distress syndrome. The present study examines the effects of tidal volume (V T) on renal function using two V T values (8 and 27 mL/kg) in anesthetized, paralyzed and mechanically ventilated male Wistar rats. Animals were randomized into two groups of 6 rats each: V T8 (V T, 8 mL/kg; 61.50 ± 0.92 breaths/min; positive end-expiratory pressure, 3.0 cmH2O; peak airway pressure (PAW), 11.8 ± 2.0 cmH2O), and V T27 (V T, 27 mL/kg; 33.60 ± 1.56 breaths/min; positive end-expiratory pressure, none, and PAW, 22.7 ± 4.0 cmH2O). Throughout the experiment, mean PAW remained comparable between the two groups (6.33 ± 0.21 vs 6.50 ± 0.22 cmH2O). For rats in the V T27 group,... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Artificial respiration; Kidney; Physiology; Glomerular filtration rate; Wistar rats. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001100017 |
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| Salgado,J.V.; Neves,F.A.; Bastos,M.G.; França,A.K.; Brito,D.J.; Santos,E.M.; Salgado Filho,N.. |
| Chronic kidney disease (CKD) is a world-wide public health problem, with adverse outcomes of kidney failure, cardiovascular disease, and premature death. This finding has led to the hypothesis that earlier recognition of kidney disease and successful intervention may improve outcome. The National Kidney Foundation, through its Kidney Disease Outcomes Quality Initiative (K/DOQI), and other National institutions recommend glomerular filtration rate (GFR) for the definition, classification, screening, and monitoring of CKD. Blood creatinine clearance, the most widely used clinical marker of kidney function, is now recognized as an unreliable measure of GFR because serum creatinine is affected by age, weight, muscle mass, race, various medications, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Kidney function; Glomerular filtration rate; Creatinine; Cystatin C; Measurement and calculation of GFR. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000600002 |
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| Figueiredo,Mariana da Silva; Malm,Christina; Mamão,Leonardo Dias; Oliveira,Juliana de; Veado,Júlio César Cambraia; Costa,Mariana Pádua; Valente,Pâmela Cristina Lopes Gurgel; Horta,Rodrigo dos Santos; Castro,Marina Lopes; Castro,Aline Gomes de; Sbaraini,Leila; Souza,Eliana Matias de. |
| ABSTRACT: Pyometra is a common disease in intact female dogs and can cause glomerulopathy and tubular injury. This study aimed to evaluate kidney injury in female dogs with pyometra, as well as progression of the injury during treatment and the markers of this condition. This study analyzed 20 intact female dogs with both clinical and sonographic diagnosis of pyometra. Dogs were treated with intravenous fluids and antibiotics, and an ovariohysterectomy was performed. The following parameters were assessed at eight separate time points: blood pressure; serum creatinine, phosphorus, and urea levels; urinalysis and urinary biochemical parameters [urinary gamma-glutamyl transferase (uGGT) and urinary protein-to-creatinine ratio (UPCR)]; glomerular filtration... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Kidney disease; Kidney function; Urinary GGT; Urinary protein-to-creatinine ratio; Glomerular filtration rate. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000500603 |
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