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Atherosclerosis and acute arterial thrombosis in rabbits: a model using balloon desendothelization without dietary intervention BJMBR
Acute thrombosis can be induced in rabbits by a triggering protocol using Russell's viper venom and histamine given after 8 months of a 1% cholesterol diet and balloon desendothelization. In the present study, we tested the hypothesis that aortic desendothelization performed 4 months before the triggering protocol without a high cholesterol diet is a highly effective and less expensive way of producing arterial atherosclerosis and thrombosis. Nineteen male New Zealand white rabbits on a normal diet were studied. The control group (N = 9) received no intervention during the 4-month observation period, while the other group (N = 10) was submitted to aortic balloon desendothelization using a 4F Fogarty catheter. At the end of this period, all animals were...
Palavras-chave: Endothelium; Histamine; Russell's viper venom; Coronary artery disease.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000300017
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Bacteria isolated from Korean black raspberry vinegar with low biogenic amine production in wine BJM
Song,Nho-Eul; Cho,Hyoun-Suk; Baik,Sang-Ho.
Abstract A high concentration of histamine, one of the biogenic amines (BAs) usually found in fermented foods, can cause undesirable physiological side effects in sensitive humans. The objective of this study is to isolate indigenous Acetobacter strains from naturally fermented Bokbunja vinegar in Korea with reduced histamine production during starter fermentation. Further, we examined its physiological and biochemical properties, including BA synthesis. The obtained strain MBA-77, identified as Acetobacter aceti by 16S rDNA homology and biochemical analysis and named A. aceti MBA-77. A. aceti MBA-77 showed optimal acidity % production at pH 5; the optimal temperature was 25 °C. When we prepared and examined the BAs synthesis spectrum during the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biogenic amines; Histamine; Acetic acid bacteria; Vinegar; Wine.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000200452
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Bioactive amines in Brazilian wines: types, levels and correlation with physico-chemical parameters BABT
Souza,Solange C.; Theodoro,Karine H.; Souza,Élson R.; Motta,Silvana da; Glória,Maria Beatriz Abreu.
The levels of ten bioactive amines and the physico-chemical characteristics of Cabernet Sauvignon, Cabernet Franc and Merlot wines from Bento Gonçalves, RS, Brazil, vintage of 1999 were investigated. The physico-chemical characteristics varied significantly: pH from 3.80 to 4.07, total acidity from 67.7 to 85.3 meq/L, alcohol content from 11.45 to 12.46 mL/100 mL and total SO2 from 9.6 to 102 mg/L. Six amines were detected in every sample - spermidine, putrescine, histamine, tyramine, serotonine and phenylethylamine. Total amine levels ranged from 2.03 to 7.60 mg/L. Putrescine was the prevalent amine, contributing with 20 to 66% of total levels. The amine profile and total levels were affected to a greater extent by vinification practices compared to grape...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Red wine; Amines; Histamine; Tyramine.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000100009
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Biogenic amines and the antioxidant capacity of juice and wine from brazilian hybrid grapevines. Repositório Alice
GOMEZ, H. A. G.; MARQUES, M. O. M; BORGES, C. O.; MINATE, I. O.; MONTEIRO, G. C.; RITSCHEL, P. S.; ZANUS, M. C.; DIAMANTE, M. S.; KLUGE, R. A.; LIMA; LIMA, G. P. P.
Some biogenic amines (BAs) are used as quality markers in grape-derived products. The prolife of 9 BAs was determined in juices and wines elaborated from hybrid grapes. Low levels of histamine, tyramine and cadaverine were found. Juices elaborated from ?BRS Rúbea? showed the highest tyramine levels (1.56 mg/L), while no histamine was found in wines elaborated from ?Seleção 34? and its higher content was detected in ?BRS Carmem? (3.55 mg/L). Juices elaborated from ?BRS Violeta? showed elevated content (472.88 mg/L) of total phenolic compounds (TPC) and mono-hydrated serotonin (6.20 mg/L), and wines elaborated from ?Violeta? presented a high serotonin mono-hydrate content (23.63 mg/L) and high antioxidant activity with FRAP test (77.24 mmol FeSO4/L). Juices...
Tipo: Artigo de periódico Palavras-chave: Juice; Histamine; Tyramine; Antioxidant activity; Serotonin; Wines.
Ano: 2020 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1128033
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Central Opioidergic System Interplay with Histamine on Food Intake in Neonatal Chicks: Role of µ-Opioid and H1/H3 Receptors Rev. Bras. Ciênc. Avic.
Jaefari-Anari,M; Zendehdel,M; Gilanpour,H; Asghari,A; Babapour,V.
ABSTRACT The present study was designed to examine the role of Opioidergic and Histaminergic systems on feeding behavior in 3-hour food deprived neonatal meat- type chicks. In experiment 1, chicks received intracerebroventricular (ICV) injection of (A) control solution, (B) α-FMH (alpha fluoromethyl histidine; 250 nmol), (C) DAMGO (µ-opioid receptor agonist, 125 pmol) and (D) α-FMH + DAMGO. Experiments 2-4 were similar to experiment 1, except chicken ICV injected with Chlorpheniramine (histamine H1 receptors antagonist; 300 nmol), famotidine (histamine H2 receptors antagonist; 82 nmol) and Thioperamide (histamine H3 receptors antagonist; 300 nmol) instead of the α-FMH. In experiments 5-8, birds ICV injected with the same procedure as experiments 1-4,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Central opioidergic; Histamine; Food intake; Broiler chicken.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2018000300595
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Chlorpheniramine impairs functional recovery in Carassius auratus after telencephalic ablation BJMBR
Garção,D.C.; Canto-de-Souza,L.; Romaguera,F.; Mattioli,R..
We determined the effect of an H1 receptor antagonist on the functional recovery of Carassius auratus submitted to telencephalic ablation. Five days after surgery the fish underwent a spatial-choice learning paradigm test. The fish, weighing 6-12 g, were divided into four groups: telencephalic ablation (A) or sham lesion (S) and saline (SAL) or chlorpheniramine (CPA, ip, 16 mg/kg). For eight consecutive days each animal was trained individually in sessions separated by 24 h (alternate days). Training trials (T1-T8) consisted of finding the food in one of the feeders, which were randomly blocked for each subject. Animals received an intraperitoneal injection of SAL or CPA 10 min after the training trials. The time spent by the animals in each group to find...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Functional recovery; Spatial-choice learning; Histamine; Chlorpheniramine; Carassius auratus; Telencephalic ablation.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000400010
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Chlorpheniramine impairs spatial choice learning in telencephalon-ablated fish Biol. Res.
ROMAGUERA,FERNANDA; MATTIOLI,ROSANA.
This work investigated the effect of the Hj receptor blockade in the forebrain of ablated Carassius auratus in a simple stimulus-response learning task using a T-maze test with positive reinforcement. The goldfish were submitted to surgery for removal of both telencephalic lobes five days before beginning the experiment. A T-shaped glass aquarium was employed, with two feeders located at the extremities of the long arm. One of the two feeders was blocked. The experimental triáis were performed in nine consecutive days. Each fish was individually placed in the short arm and confined there for thirty seconds, then it was allowed to swim through the aquarium to search for food for ten minutes (máximum period). Time to find food was analysed in seconds....
Tipo: Journal article Palavras-chave: Histamine; Learning; Teleost fish; Telencephalon.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000300010
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Compound 48/80, a histamine-depleting agent, blocks the protective effect of morphine against electroconvulsive shock in mice BJMBR
Karadag,C.H.; Dokmeci,D.; Dost,T.; Ulugol,A.; Dokmeci,I..
We have shown that morphine has an anticonvulsive effect against maximal electroconvulsive shock (MES) in mice, and this effect is antagonized by histamine H1-receptor antagonists. Brain histamine is localized both in neurons and in mast cells, and morphine is known to enhance the turnover of neuronal histamine and to release histamine from mast cells. In the present experiments, compound 48/80 was injected chronically (0.5 mg/kg on day 1, 1 mg/kg on day 2, 2 mg/kg on day 3, 3 mg/kg on day 4, and 4 mg/kg on day 5, twice daily, ip) to deplete mast cell contents. Morphine (0.001-10 mg/kg, ip; N = 20) produced a dose-dependent anticonvulsive effect against MES seizure in mice with non-depleted mast cells, whereas it did not exert any anticonvulsive effect in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Morphine; Anticonvulsive effect; Histamine; Mast cells; Compound 48/80; Electroshock.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000300011
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Differential effect of plant lectins on mast cells of different origins BJMBR
Lopes,F.C.; Cavada,B.S.; Pinto,V.P.T.; Sampaio,A.H.; Gomes,J.C..
Histamine release induced by plant lectins was studied with emphasis on the carbohydrate specificity, external calcium requirement, metal binding sites, and mast cell heterogeneity and on the importance of antibodies bound to the mast cell membrane to the lectin effect. Peritoneal mast cells were obtained by direct lavage of the rat peritoneal cavity and guinea pig intestine and hamster cheek pouch mast cells were obtained by dispersion with collagenase type IA. Histamine release was induced with concanavalin A (Con A), lectins from Canavalia brasiliensis, mannose-specific Cymbosema roseum, Maackia amurensis, Parkia platycephala, Triticum vulgaris (WGA), and demetallized Con A and C. brasiliensis, using 1-300 µg/ml lectin concentrations applied to Wistar...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mast cells; Histamine; Plant lectins.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000600016
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Dosage rapide de l'histamine dans le thon : mise au point, optimisation, applications ArchiMer
Bregeon, Nelly.
After a bibliographic analysis about histamine in tuna and thanks to a high matematical process - the experimental design method - the author has adjusted a quick proportioning method for histamine. The enzymatic technique used in this case requires a microplates reader. It was afterwards valided by comparison with HPLC methode consideres as reference.
Tipo: Text Palavras-chave: Thon Histamine; Plans cxperimentaux; Dosage enzymatiquc; Colorimetre; Test rapide; Tuna; Histamine; Experimental design method; Enzymatic analysis; Spectrophotometry; Quick test.
Ano: 1992 URL: https://archimer.ifremer.fr/doc/00464/57524/59714.pdf
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Effect of propolis extract on guines pig lung mast cell J. Venom. Anim. Toxins incl. Trop. Dis.
Orsi,R. O.; Sforcin,J. M.; Funari,S. R. C.; Gomes,J. C..
The direct effect of ethanolic extract of propolis on guinea pig lung cell suspension containing mast cells, as well as its influence on the histamine release induced by antigen (ovoalbumin 10 mug/ml) and ionophore A 23187 (3 muM) were investigated. Propolis ethanolic extract (300 mug/ml) increased the histamine release in guinea pig lung suspension containing mast cells by a cytotoxic effect. Lower concentrations of propolis had no effect on histamine release. Our results demonstrated that propolis (3, 10, 30, and 100 mug/ml) shows no significant effect on the histamine release induced by ionophore and antigen. Based on these results, we suggest that propolis could directly activate mast cells, promoting inflammatory mediators release by cytotoxic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mast cells; Allergy; Histamine; Propolis.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000100009
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Hippocampal histamine receptors and conflictive exploration in the rat: studies using the elevated asymmetric plus-maze BJMBR
Ruarte,M.B.; Orofino,A.G.; Alvarez,E.O..
The possible role of histamine receptors in the hippocampal formation on the exploratory motivation and emotionality of the rat was studied. An elevated asymmetric plus-maze composed of 4 different arms (no walls, single high wall, high and low walls and two high walls) arranged at 90o angles was used. The exploration score, considered to be an index of exploratory motivation, and the permanency score, considered to be an index of emotionality (anxiety), were determined. Histamine was administered locally into the ventral hippocampus at three different doses (9, 45 and 90 nmol). Another group of rats was also microinjected with 45 nmol of pyrilamine (a histamine H1 receptor antagonist) or ranitidine (a histamine H2 receptor antagonist) in addition to 9...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Emotionality; Motivation; Hippocampus; Histamine; Elevated asymmetric plus-maze.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001200012
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Histamine production by Enterobacter aerogenes in chub mackerel (Scomber japonicus) at various storage temperatures Ciênc. Tecnol. Aliment.
ZOU,Yu; HOU,Xiyan.
Abstract Growth of Enterobacter aerogenes and accumulation of histamine in chub mackerel (Scomber japonicus) were investigated through measuring bacterial count, histidine decarboxylase (HDC) activity and histamine content in fish samples stored at various temperatures from 4 to 37 °C. Results showed that bacterial count and HDC activity rapidly increased in chub mackerel inoculated with E. aerogenes at storage temperature above 20 °C and reached the highest values (8.64 log CFU/g and 31.68 U/g) at 37 °C. Meanwhile, fish samples stored at 25 and 37 °C for 18 h, formed histamine at above 50 mg/100 g of the potential hazard level. In contrast, bacterial growth and histamine formation were controlled for 36 h by cold storage at low temperature (4 °C)....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Histamine; Histidine decarboxylase; Enterobacter aerogenes; Chub mackerel.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612017000100076
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Human umbilical artery smooth muscle exhibits a 2-APB-sensitive capacitative contractile response evoked by vasoactive substances and expresses mRNAs for STIM, Orai and TRPC channels Biocell
Roldán Palomo,Ana Rocío; Martín,Pedro; Rebolledo,Alejandro; Enrique,Nicolás; Flores,Luis E.; Milesi,Verónica.
After depletion of intracellular Ca2+ stores the capacitative response triggers an extracellular Ca2+ influx through store-operated channels (SOCs) which refills these stores. Our objective was to explore if human umbilical artery smooth muscle presented this response and if it was involved in the mechanism of serotonin- and histamine-induced contractions. Intracellular Ca2+ depletion by a Ca2+-free extracellular solution followed by Ca2+ readdition produced a contraction in artery rings which was inhibited by the blocker of Orai and TRPC channels 2-aminoethoxydiphenyl borate (2-APB), suggesting a capacitative response. In presence of 2-APB the magnitude of a second paired contraction by serotonin or histamine was significantly less than a first one,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Human umbilical artery; Capacitative response; TRPC channels; Serotonin; Histamine.
Ano: 2012 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452012000200004
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Influence of physical damage and freezing on histamine concentration and microbiological quality of yellowfin tuna during processing Ciênc. Tecnol. Aliment.
García-Tapia,Gonzalo; Barba-Quintero,Guillermo; Gallegos-Infante,José Alberto; Aguilar,Ramón Pacheco; Ruíz-Cortés,Juan Antonio; Ramírez,José Alberto.
Yellowfin tuna has a high level of free histidine in their muscle, which can lead to histamine formation by microorganisms if temperature abuse occurs during handling and further processing. The objective of this study was to measure levels of histamine in damaged and undamaged thawed muscle to determine the effect of physical damage on the microbial count and histamine formation during the initial steps of canning processing and to isolate and identify the main histamine-forming microorganisms present in the flesh of yellowfin tuna. Total mesophilic and psicrophilic microorganisms were determined using the standard plate method. The presence of histamine-forming microorganisms was determined in a modified Niven's agar. Strains were further identified...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Yellowfin tuna; Histamine; Processing; Freezing.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612013000300012
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Potential anti-allergic action of three medicinal plants used in Amazon region: Effects on histamine release. Repositório Alice
OLIVEIRA, D. M. de; DI STASI, L. C.; PARACAMPO, N. E. N. P.; LAMEIRA, O. A.; CRESPO-LOPEZ, M. E..
Tipo: Separatas Palavras-chave: Anti-alergico; Anti-allergic; Amazon.; Histamina; Planta Medicinal.; Amazonia; Histamine; Medicinal plants..
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1004794
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Restoration of adenosine deaminase, histamine, and IgE in organs of mice injected with cobra venom followed by specific treatment and reversal period J. Venom. Anim. Toxins incl. Trop. Dis.
Lipps,B. V..
Adenosine deaminase (ADA), histamine, and IgE are endogenously present in animals. Research from this laboratory reported decreased levels of these substances in organs of mice as a consequence of sub-lethal injection of Naja kaouthia venom. This research reports that decreased ADA, histamine, and IgE levels were prevented by specific treatment and prolonged recovery periods. Adult Balb/c mice injected IM with sub-lethal venom dose were divided into five groups. Group 1 were injected with PBS; Group 2 with anti-cobra venom; and Group 3 with lethal toxin neutralizing factor (LTNF). Groups 4 and 5 were treated with IM or oral synthetic LT-10. After 24 hours, mice were sacrificed and organ homogenates were assayed for ADA, histamine, and IgE. Group 1 showed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cobra venom; Mouse organs; ADA; Histamine; IgE; Homeostasis.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992003000200007
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SUB-LETHAL INJECTION OF COBRA VENOM DECREASES ADENOSINE DEAMINASE, HISTAMINE, AND IgE IN ORGANS OF MICE J. Venom. Anim. Toxins
LIPPS,B. V..
The pharmacological substances adenosine deaminase (ADA), histamine, and IgE are endogenously present in animals. They are implicated in allergy and asthma and detectable in blood serum. This research reports the presence of ADA, histamine, and IgE at varying levels in almost all major organs of mice. This research further reports that intramuscular injection of sub-lethal dose of Naja kaouthia venom disrupted homeostasis and lowered the levels of ADA, histamine, and IgE in the organs of mice. Adult Balb/C male mice were injected with a half lethal dose of the venom. The mice were sacrificed at 2, 8, and 24 hours post-injection and different organs were collected. Organs were homogenized, centrifuged, and the supernatants were assayed for ADA, histamine,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cobra venom; Balb/C mice organs; Adenosine deaminase; Histamine; IgE; Naja kaouthia.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000100006
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Sub-lethal injection of honeybee venom decreased the levels of endogenously present substances in organs of mice J. Venom. Anim. Toxins
LIPPS,B. V..
Pharmacological substances such as adenosine deaminase (ADA), collagen, histamine, IgE, myoglobin, and nerve growth factor (NGF) are endogenously present in animals. Research from this laboratory reported decreased levels of ADA, histamine, IgE, and NGF in organs of mice injected with sub-lethal doses of cobra venom. The goal of this research is to observe the levels of ADA, collagen, histamine, IgE, myoglobin, and NGF in certain organs of mice injected with venom from the bee Apis mellifera. Adult Balb/c female mice IM injected with half lethal dose of bee venom were sacrificed after 2 and 8 hours for removal of organs. The homogenates of the organs were assayed by ELISA for ADA, collagen, histamine, IgE, myoglobin, and NGF using respective antisera....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Honeybee venom; Adenosine deaminase; Collagen; Histamine; IgE; Myoglobin; Nerve growth factor.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000200006
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The effect of L-arginine on guinea-pig and rabbit airway smooth muscle function in vitro BJMBR
Perez,A.C.; Paul,W.; Harrison,S.; Page,C.P.; Spina,D..
We have investigated the effects of L-arginine, D-arginine and L-lysine on airway smooth muscle responsiveness to spasmogens in vitro. Both L-arginine and D-arginine (100 mM) significantly reduced the contractile potency and maximal contractile response to histamine but not to methacholine or potassium chloride in guinea-pig epithelium-denuded isolated trachea. Similarly, the contractile response to histamine was significantly reduced by L-arginine (100 mM) in rabbit epithelium-denuded isolated bronchus. The amino acid L-lysine (100 mM) failed to significantly alter the contractile potency of histamine in guinea-pig isolated trachea (P>0.05). In guinea-pig isolated trachea precontracted with histamine, both L-arginine and D-arginine produced a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: L-Arginine; D-Arginine; L-Lysine; Histamine; H1 receptors.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000600014
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