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131I-induced changes in rat thyroid gland function BJMBR
Torlak,V.; Zemunik,T.; Modun,D.; Capkun,V.; Pesutic-Pisac,V.; Markotic,A.; Pavela-Vrancic,M.; Stanicic,A..
Therapeutic doses of 131I administered to thyrotoxic patients may cause thyroid failure. The present study used a rat model to determine thyroid function after the administration of different doses of 131I (64-277 µCi). Thirty male Fisher rats in the experimental group and 30 in the control group (untreated) were followed for 6 months. The animals were 4 months old at the beginning of the experiment and were sacrificed at an age of 9 months. Hormone concentration was determined before 131I administration (4-month-old animals) and three times following 131I administration, when the animals were 7, 8, and 9 months old. The thyroid glands were removed and weighed, their volume was determined and histopathological examination was performed at the end of the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Thyroid gland; 131I; Hormones; Histopathology; T3; T4; TSH.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000800009
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Acute toxicity and histopathology in ornamental fish amazon bluespotted corydora (Corydoras melanistius) exposed to formalin. Repositório Alice
SANTOS, R. F. B.; DIAS, H. M.; FUJIMOTO, R. Y..
2012
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Histopathology.
Ano: 2012 URL: http://www.alice.cnptia.embrapa.br/handle/doc/944640
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Acute Toxicity by Water Containing Hexavalent or Trivalent Chromium in Native Brazilian Fish, Piaractus mesopotamicus: Anatomopathological Alterations and Mortality. Repositório Alice
CASTRO, M. P.; MORAES, F. R. de; FUJIMOTO, R. Y.; CRUZ, C. da; BELO, M. A. de A.; MORAES, J. R. E. de..
This study evaluated the toxicity of hexavalent and trivalent compounds of chromium to the pacu, Piaractus mesopotamicus, in acute exposures of 96 h through mortality and histopathological responses. Hexavalent otassium dichromate was more toxic than trivalent compounds of chromium chloride, chromium oxide and chromium carbochelate. Sufficient mortalities occurred only with potassium dichromate to yield an LC50 value at 124.2 mg L-1. Hexavalent chromium caused reversible and irreversible lesions, which may affect organ functionality. Histopathological evaluation showed that trivalent chromium caused lesions of lower severity. Pacu subjected to different concentrations of chromium carbochelate showed no histopathological changes in the kidneys, liver, skin...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Chromium; Toxicity; Piaractus mesopotamicus; Histopathology.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1002178
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An infection of Ruditapes decussatus (Bivalvia) by Rickettsia ArchiMer
Mialhe, Eric; Chagot, Dominique; Boulo, Viviane; Comps, Michel; Ruano, Francisco; Grizel, Henri.
The authors report the presence of a Rickettsia in Ruditapes decussatus from natural populations of the Algarve (Portugal). Light microscopic shows infections of varying importance in gill tissues. Some enclose small procaryotic colonies (cp) scattered in all lamellae; in others, the colonies are scarce and hypertrophic (100 mu m). These different pictures suggest an amplification process. Digestive diverticulae may also be infected, but to a lesser extent. The ultrastructural features of this intravacuolar (mvd: densified vacuolar membrane) procaryote (P) and its multiplication by scission without a complex developmental cycle allows its classification in the order Rickettsiales.
Tipo: Text Palavras-chave: Ruditapes philippinarum; Pathogens; Histopathology; Pathology.
Ano: 1987 URL: http://archimer.ifremer.fr/doc/1987/acte-3107.pdf
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An unusual case of ectopic tungiasis with pseudoepitheliomatous hyperplasia BJID
Heukelbach,J.; Sahebali,S.; Van Marck,E.; Sabóia Moura,R.C.; Feldmeier,H..
Tungiasis is caused by the penetration of the female sand flea Tunga penetrans into the epidermis, and subsequent hypertrophy of the parasite. In most cases lesions are confined to the feet. During a cross-sectional study, an unusual case of ectopic tungiasis in the inguinal area was detected. Histological examination of tissue samples showed a remarkable pseudoepitheliomatous aspect of the epidermis. Clinical features and differential diagnoses are discussed.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Ectoparasite; Tunga penetrans; Tungiasis; Ectopic localization; Histopathology; Brazil.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000600012
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Anesthesia by sprinkling method in the gills of tambaqui Colossoma macropomum does not influence intensity and morphology of monogeneans. Repositório Alice
BOIJINK, C. L.; MACIEL, P. O.; TAVARES-DIAS, M.; IWASHITA, M. K. P.; MORAIS, M. S.; HIDE, D. M. V.; SOUZA, N. C.; COUTO, M. V. S.; MENESES, J. O.; CUNHA, F. S.; FUJIMOTO, R. Y..
Anestesia por meio de aspersão nas brânquias de tambaqui Colossoma maropomum não influencia a intensidade e a morfologia de monogeneas. O presente estudo avalia a influência da anestesia sobre a fauna parasitária de monogeneas em peixes, sua intensidade e sua viabilidade.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Tambaqui; Parasitology; Animal welfare; Humane slaughter; Histopathology; Parasitologia; Bem-estar animal; Abate humanitário; Histopatologia.
Ano: 2017 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1073358
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Antifibrotic effects of total or partial application of amniotic membrane in hepatic fibrosis Anais da ABC (AABC)
MAMEDE,KARINA M.; SANT’ANNA,LUCIANA B..
Abstract: Liver fibrosis is the final common pathway of chronic liver diseases, having cirrhosis as a possible progression, which has liver transplantation as the only effective treatment. Human amniotic membrane represents a potential strategy as a therapy for liver fibrosis, due to its anti-inflammatory, anti-fibrotic and immunomodulatory properties. The aim of this study was to evaluate amniotic membrane effects as a treatment for hepatic fibrosis induced in rats by bile duct ligation (BDL), verifying alterations between two different forms of amniotic membrane application, around all the lobes of the liver and around only one lobe of the liver. Two weeks after inducing fibrosis, an amniotic membrane fragment was applied to the surface of the liver,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Amniotic membrane; Histopathology; Immunohistochemistry; Liver fibrosis; Myofibroblasts.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500702
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Appraisal of acute oral toxicity of glucuronoxylan hydrogel from Mimosa pudica seeds BJPS
Muhammad,Gulzar; Hussain*,Muhammad Ajaz; Ashraf,Muhammad Umer; Naeem-ul-Hassan,Muhammad; Bukhari,Syed Nasir Abbas.
Glucuronoxylan hydrogel (GXH) isolated from M. pudica seeds was assessed for acute toxicology in albino mice that were alienated into four groups. Three groups, i.e., II, III and IV received GXH at a dose of 1, 2 and 5 g/kg, respectively while group I was retained untreated and provided routine diet. After administering GXH, mice were examined for vomiting, diarrhea, allergy and tremors for 8 h. All animals were carefully observed for food and water consumption at 1, 2, 3, 7 and 14 day after administering GXH. At the end of studies, blood samples were drawn for investigation of hematological and biochemical parameters. All animals were sacrificed, relative body weight of vital organs was calculated and their histopathology was studied. It was concluded...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Glucuronoxylan; Acute toxicity; Histopathology; Toxicology; Mimosa pudica.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000300619
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Aspectos nutricionais para a tilápia-do-Nilo. Repositório Alice
OTA, E. do C..
Os aspectos nutricionais são relevantes para otimizar a produção da tilápia-do-Nilo e redução do impacto ambiental causado pela atividade. Em função do potencial no escopo dos aspectos nutricionais, estudos precisam ser incentivados acerca da qualidade das rações comerciais, uso de extratos de plantas e adubação de viveiros com cama-de-frango, considerando a variedade de sistemas de produção, fases de desenvolvimento dos peixes, características climáticas do local de produção e condição imunológica dos animais. Portanto, o objetivo deste estudo foi avaliar a qualidade de rações comerciais para tilápiado-Nilo em crescimento; testar a incorporação do extrato aquoso de folhas de Serjania marginata na dieta da tilápia; e verificar os efeitos da adubação com...
Tipo: Tese/dissertação (ALICE) Palavras-chave: Nutrição Animal; Histopatologia; Planta Medicinal; Peixe; Tilápia Nilótica; Oreochromis Niloticus; Animal nutrition; Histopathology; Medicinal plants; Fish.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1112678
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Avaliação da virulência de isolados de Corynebacterium pseudotuberculosis em camundongos BALB/c Infoteca-e
ROSINHA, G. M. S.; MELO, P. R. de; SANTOS, L. R. dos; CARVALHO, C. E. G.; ALVARENGA, L. C. O.; ANDRADE, G. B.; SOARES, C. O..
Corynebacterium pseudotuberculosis é uma bactéria Gram-positiva, agente etiológico da linfadenite caseosa (LC) em pequenos ruminantes e causadora de piogranulomas, linfangite ulcerativa, mastite e dermatite ulcerativa em bovinos, que são doenças de grande relevância médica e veterinária. Esta doença é de difícil controle e a vacinação é a maneira mais eficiente de preveni-la nos rebanhos. Objetivou-se neste estudo selecionar cepas virulentas de C. pseudotuberculosis, a partir de cinco isolados obtidos de caprinos e ovinos, para uso em estudos de desafio em testes de novas vacinas contra linfadenite caseosa em camundongos. Primeiramente, os isolados foram caracterizados bioquimicamente com o kit API Coryne (APIbioMerieux, Inc., La Balme les Grottes, France)...
Tipo: Boletim de Pesquisa e Desenvolvimento (INFOTECA-E) Palavras-chave: Corynebacterium Pseudotuberculosis; Histopatologia; Linfadenite Caseosa; Patogenicidade; Caseous lymphadenitis; Virulence; Histopathology.
Ano: 2018 URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/1106896
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Bartholin’s gland adenoma in a Saanen goat Ciência Rural
Moreira,Jessica Regina; Oliveira,Thalita Evani Silva de; Tongu,Eriky Akio de Oliveira; Leite,Raissa Oliveira; Nogueira,Geison Morel; Michelazzo,Mariana de Mello Zanim; Delfiol,Diego José Zanzarini; Saut,João Paulo Elsen; Headley,Selwyn Arlington.
ABSTRACT: Tumors affecting Bartholin’s gland are considered rare in human medicine; there are few reports in the veterinary literature, with descriptions occurring only in cows. This article described the clinical and pathological findings associated with Bartholin’s gland adenoma in a goat. Clinically, a 7-year-old pregnant Saanen goat presented bilateral enlargement of the vulva that did not regress spontaneously after parturition. Grossly, these vulvar masses were multilobulated, contained cystic areas from which oozed a whitish fluid. Histopathology revealed an adenoma characterized by the proliferation of irregularly shaped neoplastic epithelial cells that formed tubular to glandular-like structures. These neoplastic cells demonstrated moderate...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Histopathology; Ki-67 protein; Adenoma; Major vestibular glands.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000100501
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Bonamia sp. (Protozoa, Haplosporidia) parásito de Ostrea puelchana D’Orbigny, (Mollusca, Bivalvia) en el Golfo San Matías (Patagonia Argentina): Histopatología, identificación e infección OceanDocs
Kroeck, M.A..
Los moluscos bivalvos son organismos sedentarios que establecen una relación íntima no sólo entre ellos, sino también con el espacio que ocupan y con sus condiciones fisicoquímicas. Sus poblaciones pueden ser hospedadoras de múltiples organismos patógenos (virus,bacterias, hongos, protistas y metazoos), cuya presencia es regulada eficazmente a niveles infra, meta y suprapoblacionales en ambientes silvestres, no provocando, salvo excepcionalmente, impactos severos. Los cultivos a escala comercial producen concentraciones de individuos, con la consiguiente alteración del medio y del equilibrio natural en la relación parásito-hospedador, generándose condiciones apropiadas para el desarrollo de enfermedades. Entre los años 1995 y 1996 se instala, en la zona...
Tipo: Theses and Dissertations Palavras-chave: Fishery biology; Marine molluscs; Parasitology; Protozoan diseases; Histopathology; Spatial distribution; Environmental conditions; Methodology; Examinations.
Ano: 2005 URL: http://hdl.handle.net/1834/5244
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Bothrops alternatus ENVENOMING IN YOUNG DOGS J. Venom. Anim. Toxins
PEREZ,O. A. DE; KOSCINCZUK,P.; FLINTA,S. M.; MAIDANA,H. R.; SANCHEZ NEGRETTE,M..
Bothrops alternatus venom was intramuscularly inoculated (3 mg/kg) into 12 dogs, 30 to 65 days old. Spontaneous bleeding commenced twenty minutes later. Blood samples obtained 3 and 20 minutes after venom inoculation presented spontaneous clotting formation. Plasmatic fibrinogen decreased within 3 minutes. Partial thromboplastin time (PTT) and one-stage prothrombin time (PT) were found. Plasma did not coagulate 40 minutes after inoculation. Platelet counts did not vary but their function was altered. Histopathology pointed out severe muscular necrosis and massive hemorrhage in the inoculation area. Regional ganglia showed intense hemorrhage. The 45 and 65-day-old animals showed alveolar thickening of the septum and generalized congestion, but the...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Dogs; Bothrops alternatus; Coagulation; Histopathology.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301997000100006
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Canine visceral leishmaniasis: a remarkable histopathological picture of one asymptomatic animal reported from Belo Horizonte, Minas Gerais, Brazil Arq. Bras. Med. Vet. Zootec.
Xavier,S.C.; Chiarelli,I.M.; Lima,W.G.; Gonçalves,R.; Tafuri,W.L..
A remarkable histopathological picture of one asymptomatic dog naturally infected with Leishmania infantum (syn. chagasi) has been presented. Intracellular parasites were ease found in macrophages of all exanimated organs, especially in skin. Embedded paraffin tissues of liver, spleen, axillary and popliteal lymph nodes, and skin (ear, muzzle and abdomen) were stained by hematoxylin and eosin and by immunocytochemical reaction (streptoavidin-peroxidase method) to detect parasites. All organs showed an intense parasitism associated to severe pathological changes. All lymph nodes had conspicuous histological architecture alterations. Lymphocytes were replaced by macrophages stuffed with an intense number of amastigotes forms of Leishmania. The lymphoid...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dog; Leishmania infantum; Histopathology.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000600004
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Clostridium perfringens types A and D associated with enterotoxemia in an 18-month-old goat J. Venom. Anim. Toxins incl. Trop. Dis.
Miyashiro,S.; Nassar,A. F. C.; Del Fava,C.; Cabral,A. D.; Silva,M..
Postmortem examination of a Boer buck that died peracutely revealed bowel and liver diffusely congested and edematous. Kidney was apparently edematous. Clostridium perfringens type A was isolated from bowel and type D from kidney. Microscopic examination revealed large areas of necrosis in the renal cortex and medulla (pulpy kidney disease), hyperemia and centrilobular necrosis of the liver, necrosis of the small-intestine wall, pulmonary edema and congestion, intense hyperemia of the cerebellum, hyperemia and edema of the brain.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Goats; Enterotoxemia; Pulpy kidney disease; Clostridium perfringens type A; Clostridium perfringens type D; Histopathology.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000400017
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Comparative evaluation of the susceptibility of cultivated fishes to the natural infection with myxosporean parasites and tissue changes in the host BJB
MARTINS,M. L.; SOUZA,V. N. de; MORAES,J. R. E. de; MORAES,F. R. de; COSTA,A. J. da.
The purpose of the study was to evaluate the susceptibility of 4 important cultivated fishes to sporozoan parasites. Fishes were collected bimonthly from a pond for a period of 1 year. Myxobolus colossomatis and Henneguya piaractus were found in the internal organs and gills, respectively. The combined incidence of parasitism by both myxozoa was 97.3% in pacu (Piaractus mesopotamicus), 33.3% in hybrid tambacu (Piaractus mesopotamicus x Colossoma macropomum), 5.6% in tambaqui (Colossoma macropomum) and 0% in carp (Cyprinus carpio). Pacu was the most susceptible fish and was parasitized 79.2% in the gills, 66.7% in the kidney and 50% in the spleen. Histopathological evaluation of the gills showed hemorrhages, inflammatory reaction with mononuclear cells and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Myxozoa; Susceptibility; Histopathology; Cultivated fish.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-71081999000200010
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Comparative study of histopathology and immunohistochemistry of indefinite round cell cutaneous tumors and characterization of canine lymphoma Arq. Bras. Med. Vet. Zootec.
Machado,L.H.A.; Palumbo,M.I.P.; Zahn,F.S.; Amorim,R.L.; Farias,M.R.; Werner,J.; Torres Neto,R.; Rodrigues,J.C.; Oliveira,F.C..
With the purpose of shedding light on some doubts in veterinary oncology, the present article intends to compare the results of histopathological and immunohistochemical examinations of unspecific round cell neoplasia, to realize immunophenotyping of canine lymphoma cases, to establish the T or B origin of neoplastic cells, and to determine the degree of proliferation and apoptosis of lymphomas by immunohistochemistry. Of 11 animals presenting immunohistochemical diagnosis of lymphoma, five had been diagnosed as Lymphoma by HE staining of histopathological slides and six had been classified as unspecific round cell neoplasia. All cases submitted to immunohistochemical examination were T-cell lymphomas. There was a positive correlation between cell...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dog; Histopathology; Immunohistochemistry; Round cell neoplasia; Lymphoma.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352015000100032
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Comparison of the effects of the dietary addition of two lactic acid bacteria on the development and conformation of sea bass larvae, Dicentrarchus labrax, and the influence on associated microbiota ArchiMer
Lamari, Faouzi; Castex, Mathieu; Larcher, Thibaut; Ledevin, Mireille; Mazurais, David; Bakhrouf, Amina; Gatesoupe, Joel.
Probiotics may have many effects on health and development of fish larvae. One of the most promising is related to spinal conformation, though the mode of action is not clearly understood. The present study attempted to investigate the effects of two strains of lactic acid bacteria on associated microbiota, histological development and gene expression. Sea bass larvae were fed since 5 dph (day post hatch) with either a standard control diet (Diet C), or the same diet supplemented with Pediococcus acidilactici MA18/5M (Diet P), or with an autochthonous strain of Lactobacillus casei (X2; Diet L). The two lactic acid bacteria were incorporated in the diets at the levels of 106 and 107 CFU (colony forming units) g-1 in two consecutive experiments,...
Tipo: Text Palavras-chave: Fish larvae; Probiotics; Microbiota; Histopathology; Gene expression; DGGE.
Ano: 2013 URL: http://archimer.ifremer.fr/doc/00108/21966/19673.pdf
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Constitutional and somatic methylation status of DMRH19 and KvDMR in Wilms tumor patients Genet. Mol. Biol.
Cardoso,Leila C.A.; Castaño,Jair A. Tenorio; Pereira,Hanna S.; Lima,Maria Angélica de F.D.; Santos,Anna Cláudia E. dos; Faria,Paulo S. de; Ferman,Sima; Seuánez,Héctor N.; Nevado,Julián B.; Almeida,José Carlos Cabral de; Lapunzina,Pablo; Vargas,Fernando R..
The most frequent epigenetic alterations in Wilms tumor (WT) occur at WT2, assigned to 11p15. WT2 consists of two domains: telomeric domain 1 (DMRH19) that contains the IGF2 gene and an imprinted maternally expressed transcript (H19) and centromeric domain 2 (KvDMR) that contains the genes KCNQ1, KCNQ1OT1 and CDKN1C. In this work, we used pyrosequencing and MS-MLPA to compare the methylation patterns of DMRH19/KvDMR in blood and tumor samples from 40 WT patients. Normal constitutional KvDMR methylation indicated that most of the epigenetic alterations in WT occur at DMRH19. Constitutional DMRH19 hypermethylation (HM DMRH19) was observed in two patients with Beckwith-Wiedemann syndrome. Pyrosequencing and MS-MLPA showed HM DMRH19 in 28/34 tumor samples:...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Epigenetic; Histopathology; Methylation; MS-MLPA; Pyrosequencing.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000500002
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Diagnosis to Detect Porcine Transmissible Gastroenteritis Virus (TGEV) by Optical and Transmission Electron Microscopy Techniques International Journal of Morphology
Martins,A. M. C. R. P. F; Bersano,J. G; Ogata,R; Amante,G; Nastari,B. D. B; Catroxo,M. H. B.
The porcine transmissible gastroenteritis is a highly severe contagious disease, caused by virus of the Coronaviridae family, genus Coronavirus. Its epizootic shape can reach a rate of up to 100% mortality in piglets under two weeks of age as a result of severe dehydration. In this study fragments of small intestine and stool samples were collected from 75 autopsied pigs from properties. The samples of the fragments were frozen and sent to the Laboratory of Electron Microscopy, Instituto Biológico, SP, Brazil, for histological and transmission electron microscopic analyses. According to histological H&E technique, atrophy, villous necrosis and destruction of the enterocytes were observed in 35 (46.6%) out of the 75 fragments of the small intestine...
Tipo: Journal article Palavras-chave: Porcine Transmissible Gastroenteritis; Coronavirus; Histopathology; Transmission Electron Microscopy.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200059
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