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Characterization and Cytotoxic Evaluation of Silver and Gold Nanoparticles Produced with Aqueous Extract of Lavandula dentata L. in Relation to K-562 Cell Line BABT
Justus,Barbara; Arana,Andrés Fernando Montenegro; Gonçalves,Melissa Marques; Wohnrath,Karen; Boscardin,Patrícia Mathias Döll; Kanunfre,Carla Cristine; Budel,Jane Manfron; Farago,Paulo Vitor; Paula,Josiane de Fátima Padilha de.
Abstract Metallic nanoparticles have great potential as a chemotherapeutic agent. The aim of this study was to develop and characterize silver and gold nanoparticles using a simple method, as well as evaluating the potential cytotoxic activity in relation to the K-562 cell line. For the synthesis, a solution containing the metallic ions was subjected to magnetic stirring with the aqueous extract of Lavandula dentata L. and a change of colour was observed. With the data obtained from the analyses we concluded that the nanoparticles were successfully obtained by a simple and green method using the aqueous extract of L. dentata. The obtained nanoparticles presented a reduced size, a low level of polydispersion, and a homogenous spherical shape. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Green synthesis; Metallic nanoparticles; Myelogenous leukemia line; Cytotoxic potential; Lamiaceae.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100420
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Silver and gold nanoparticles from tannic acid: synthesis, characterization and evaluation of antileishmanial and cytotoxic activities Anais da ABC (AABC)
LOPES,LOURDES C.S.; BRITO,LUCAS M.; BEZERRA,THAYLLAN T.; GOMES,KLEYTON N.; CARVALHO,FERNANDO A. DE A.; CHAVES,MARIANA HELENA; CANTANHÊDE,WELTER.
Abstract Gold (Au0) and silver (Ag0) nanoparticles were synthesized using tannic acid (TA) as both reducing and stabilizer. Nanoparticles formation, stability, and interaction with TA were compared to citrate-coated nanoparticles and monitored by UV-Vis, zeta potential, and transmission electron microscopy. TA coating resulted in a red-shift and broadening of bands compared to citrate-coated nanoparticles (NPs-Cit). AgNPs-TA and AuNPs-TA are negatively charged with mean surface charge of -29.4 mV and -29.6 mV, respectively. TEM images showed polydispersety of AuNPs-TA (6-42 nm) and aggregation of AgNPs-TA (12-71 nm). In vitro assays of Leishmania amazonensis promastigotes showed an increment of antileishmanial activity for AgNPs-TA in relation to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Green synthesis; Leishmaniasis; Metallic nanoparticles; Tannic acid.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000602679
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