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Effect of Sapindus trifoliatus on hyperalgesic in vivo migraine models BJMBR
Arulmozhi,D.K.; Veeranjaneyulu,A.; Bodhankar,S.L.; Arora,S.K..
Phytotherapies have offered alternative sources of therapy for migraine and gained much importance in prophylactic treatment. Sapindus trifoliatus is a medium-sized deciduous tree growing wild in south India that belongs to the family Sapindaceae. The pericarp is reported for various medicinal properties. A thick aqueous solution of the pericarp is used for the treatment of hemicrania, hysteria or epilepsy in folklore medicine. We have investigated the antihyperalgesic effects of the lyophilized aqueous extract of S. trifoliatus in animal models predictive of experimental migraine models using morphine withdrawal-induced hyperalgesia on the hot-plate test and on 0.3% acetic acid-induced abdominal constrictions in adult male Swiss albino mice. The extract...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sapindus trifoliatus; Hyperalgesia; Migraine; Dopamine; D2 receptor; Morphine withdrawal.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000300019
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Effect of vitamin D therapy in addition to amitriptyline on migraine attacks in pediatric patients BJMBR
Cayir,A.; Turan,M.I.; Tan,H..
The purpose of this study was to investigate the effect of supplementary vitamin D therapy in addition to amitriptyline on the frequency of migraine attacks in pediatric migraine patients. Fifty-three children 8-16 years of age and diagnosed with migraine following the International Headache Society 2005 definition, which includes childhood criteria, were enrolled. Patients were classified into four groups on the basis of their 25-hydroxyvitamin D [25(OH)D] levels. Group 1 had normal 25(OH)D levels and received amitriptyline therapy alone; group 2 had normal 25(OH)D levels and received vitamin D supplementation (400 IU/day) plus amitriptyline; group 3 had mildly deficient 25(OH)D levels and received amitriptyline plus vitamin D (800 IU/day); and group 4...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Children; Migraine; Vitamin D.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000400349
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The synergetic modulation of the excitability of central gray matter by a neuropeptide: two protocols using excitation waves in chick retina Anais da ABC (AABC)
Lima,Vera M.F. de; Piqueira,José R.C.; Hanke,Wolfgang.
The isolated chick retina provides an in vitro tissue model, in which two protocols were developed to verify the efficacy of a peptide in the excitability control of the central gray matter. In the first, extra-cellular potassium homeostasis is challenged at long intervals and in the second, a wave is trapped in a ring of tissue causing the system to be under self-sustained challenge. Within the neuropil, the extra-cellular potassium transient observed in the first protocol was affected from the initial rising phase to the final concentration at the end of the five-minute pulse. There was no change in the concomitants of excitation waves elicited by the extra-cellular rise of potassium. However, there was an increase on the elicited waves latency and/or a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Extra-cellular potassium; Migraine; Neuronal-glial dynamics; Somatostatin; Spread depression.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000100006
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