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| Registros recuperados: 11 | |
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| ALENCAR,DANIEL B.; MELO,ARTHUR A.; SILVA,GISELLE C.; LIMA,REBECA L.; PIRES-CAVALCANTE,KELMA M.S.; CARNEIRO,RÔMULO F.; RABELO,ADRIANA S.; SOUSA,OSCARINA V.; VIEIRA,REGINE H.S.F.; VIANA,FRANCISCO A.; SAMPAIO,ALEXANDRE H.; SAKER-SAMPAIO,SILVANA. |
| Marine invertebrates are capable of synthesizing bioactive compounds, which may be beneficial to human health. The aim of this study was to evaluate the antioxidant, hemolytic, antimicrobial and cytotoxic activities of crude extract (70% EtOH), and dichloromethane (DCM), ethyl acetate (EtOAc), and aqueous (Aq) fractions of the marine zoanthid Palythoa caribaeorum. The phenolic compound contents of the crude extract, DCM, EtOAc and Aq fractions were 12.33, 18.17, 10.53, and 3.18 mg GAE per gram, respectively. DPPH radical scavenging activity showed slight variation. IC50 of crude extract, DCM, EtOAc and Aq fractions were 11.13, 11.25, 11.74, and 11.28 µg mL-1, respectively. Among the sample, ferrous ion chelating was the highest in crude extract (IC50... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biological activity; Marine invertebrate; Natural product; Sphenopidae. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000201113 |
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| Meneses,J.O.; Couto,M.V.S. do; Sousa,N.C.; Cunha,F. dos S.; Abe,H.A.; Ramos,F.M.; Chagas,E.C.; Chaves,F.C.M.; Martins,M.L.; Maria,A.N.; Carneiro,P.C F.; Fujimoto,R.Y.. |
| ABSTRACT The phythotherapy is an alternative to use of chemotherapeutical agents against monogenean infection. This study evaluated the anthelmintic activity of essential oil Ocimum gratissimum against monogenean Cichlidogyrus tilapiae as well as its acute toxicity in tilapia juveniles. The mean lethal concentration (LC50) and different concentrations of the essential oil, both in vitro and in vivo assays (short and long-term baths) were assessed. The LC50 was 40.70mg.L-1 and in the in vitro assay this concentration showed 80% efficacy at the last two hours and in the in vivo assay 65.87% efficacy in long-term bath. However, it provoked morphological alterations on the gills such as hyperplasia and edema. The parasites exposure at the highest concentration... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Disease; Freshwater fish; Helminth; Natural product; Treatment. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000200497 |
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| Castagnino, Guido Laercio; UFBA; Orsi, Ricardo de Oliveira; Unesp - Botucatu; Funari, Silvia Regina da Cunha; Unesp - Botucatu. |
| O presente trabalho teve como objetivo verificar o efeito do éster de sacarose no controle da infestação do ácaro Varroa destructor em abelhas africanizadas. Nos testes “in vitro”, testou-se o produto em abelhas e ácaros com cinco concentrações diluídas em água (T0: 100% de água destilada; T1: 0,5%; T2: 1%; T3: 2,0%; T4: 5% e T5: 10% de éster de sacarose). Nos testes de campo, o delineamento experimental utilizado foi inteiramente casualizado, com quatro tratamentos e sete repetições, totalizando 28 colônias, sendo sete delas como controle, sete com 0,1% de éster de sacarose, sete com 0,2% de éster de sacarose e sete colmeias com 0,5% éster de sacarose, diluídas em água. Nos testes “in vitro” com concentração de 0,5%, o éster de sacarose promoveu a... |
| Tipo: Pesquisa de campo |
Palavras-chave: 5.04.00.00-2 Apis mellifera; Ácaro; Bioacaricida; Produto natural Produção animal Apis mellifera; Mite; Bioacaricide; Natural product. |
| Ano: 2009 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/4988 |
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| RIBEIRO,Suzana Cardoso; CASTELO,Antonielson Silva; SILVA,Bruna Marjara Picanço da; CUNHA,Andreza da Silva; PROIETTI JÚNIOR,Aldo Aparecido; OBA-YOSHIOKA,Eliane Tie. |
| ABSTRACTIn fish farmings, diseases can be reduced by using immunostimulants. The aim of this study was to evaluate the immunostimulant potential of Mentha piperita in tambaqui fed with 0, 0.5, 1.0 and 1.5% of oil per kg of commercial fish feed. The fish were inoculated with Aeromonas hydrophila to challenge them. Hematological and biochemical parameters were determined after 30 days of feeding and seven days after the challenge. There was no mortality and M. piperita oil did not influence fish production parameters. However, blood hemoglobin concentration (Hb) increased in the fish fed with 0.5 and 1.5% of oil per kg of diet; albumin increased in those fed with 1.0%; cholesterol increased in all groups with oil; and triglycerides increased in those fed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Immune system; Natural product; Bacterial challenge; Biochemistry. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672016000100099 |
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| TOMAZONI,ELISA Z.; PANSERA,MÁRCIA R.; PAULETTI,GABRIEL F.; MOURA,SIDNEI; RIBEIRO,RUTE T.S.; SCHWAMBACH,JOSÉLI. |
| Several volatile natural compounds produced by plant secondary metabolism have been proven to present antimicrobial action, enabling their use in phytopathogen control. They also present low environmental impact when compared to conventional pesticides. Essential oils contain these compounds and can be found in several plant species, such as Lippia alba (Mill.) N.E. Brown (Verbenaceae). Essential oils of four chemotypes of L. alba, characterized by their major compounds, namely camphor, citral, linalool and camphor/1,8-cineole, were tested against the phytopathogen Alternaria solani Sorauer (Pleosporaceae), which causes early blight on tomatoes and is responsible for great economic losses regarding production. Essential oils antifungal action was tested in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Citral; Early blight; Natural product; Phytopathogen. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000300999 |
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| XU,Li-na; LU,Bi-nan; HU,Ming-ming; XU,You-wei; HAN,Xu; QI,Yan; PENG,Jin-yong. |
| Berberine, a constituent of some traditional Chinese medicinal plants, has been reported to have cytotoxicity effects on different human cancer cell lines. There is no available information about the effects and mechanism of action of berberine on human colon cancer cell line HCT-8. In this paper, the cytotoxicity of berberine on HCT-8 cancer cells was investigated by MTT assay, fluorescence microscopy and flow cytometry analysis. Our data revealed that berberine could significantly inhibit the growth of HCT-8 cells in a dose- and time-dependent manner. Morphology of apoptotic cells was studied with acridine orange/ethidium bromide staining. The concentrations of lactate dehydrogenase and both acid and alkaline phosphatases were significantly increased in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Apoptosis; Cell cycle arrest; Death receptor pathway; Mitochondrial pathway; Natural product. |
| Ano: 2012 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452012000300003 |
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| Begrem, Simon; Ivaniuk, Flora; Gigout Chevalier, Frederique; Kolypczuk, Laetitia; Bonnetot, Sandrine; Leroi, Francoise; Grovel, Olivier; Delbarre-ladrat, Christine; Passerini, Delphine. |
| Carnobacterium maltaromaticum and Carnobacterium divergens, isolated from food products, are lactic acid bacteria known to produce active and efficient bacteriocins. Other species, particularly those originating from marine sources, are less studied. The aim of the study is to select promising strains with antimicrobial potential by combining genomic and phenotypic approaches on large datasets comprising 12 Carnobacterium species. The biosynthetic gene cluster (BGCs) diversity of 39 publicly available Carnobacterium spp. genomes revealed 67 BGCs, distributed according to the species and ecological niches. From zero to six BGCs were predicted per strain and classified into four classes: terpene, NRPS (non-ribosomal peptide synthetase), NRPS-PKS (hybrid... |
| Tipo: Text |
Palavras-chave: Lactic acid bacteria; Antimicrobial activity; Carnobacteriumspp; Hydrogen peroxide; Bacteriocin; RiPP; NRPS; Terpene; Natural product; Genome mining. |
| Ano: 2020 |
URL: https://archimer.ifremer.fr/doc/00641/75335/75999.pdf |
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| Ávila,Renato Ivan de; Ferreira,Camila Carvalho; Alvarenga,Cátia Belo Mattos; Vieira,Marcelo de Sousa; Cortez,Alane Pereira; Batista,Aline Carvalho; Costa,Elson Alves; Valadares,Marize Campos. |
| This study evaluated the safety of Lafoensia pacari A. St.-Hil. (Lythraceae) stem bark hydroalcoholic extract (LPE) through acute and subchronic toxicological assessments in mice. In the acute toxicity evaluation, a single 2000 mg/kg oral dose of LPE was administered to mice and clinical observations were conducted for 14 days. For subchronic toxicity, LPE doses (6.25-1000 mg/kg) were administered orally for 28 days and biochemical, hematological, histopathological analyses and renal and liver expression of Ki-67 were carried out. The acute oral toxicity evaluation of LPE showed no toxicity in mice and it was was classified as category 5 (LD50>2000-5000 mg/kg). In a repeated dose 28-day toxicity study, LPE (100-1000 mg/kg) led to an increase in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mangava-brava; Lafoensia pacari/evaluation; Medicinal plant; Natural product. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100595 |
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| Croge,Camila Pereira; Cuquel,Francine Lorena; Pintro,Paula Toshimi Matumoto. |
| ABSTRACT: The unique chemical composition of yerba mate and its functionalities suggest that it needs to be explored for its innovation potential. New uses may boost consumption, surpassing the traditional consumption barrier, and making yerba mate accessible on a global level. Thus, to highlight the importance of yerba mate as a potential source of agro-economic resources, we present a review on its botanical, ecological, agronomic, and industrial aspects, along with information on the biochemical composition of this species and its biological activity. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ilex paraguariensis; Natural product; Agro-economic resources. |
| Ano: 2021 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162021000501801 |
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| Registros recuperados: 11 | |
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