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Registros recuperados: 9
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Activities, procedures and doses in pediatric patients due to radiopharmaceuticals BABT
Oliveira,Silvia Maria Velasques de; Boasquevisque,Edson Mendes; Santos,Felipe Sima dos; Biancardi,Rodrigo.
An investigation performed between 2003 and 2005 in sixteen selected public and private institutions in Northeast, Southeast and South geographical regions of Brazil evaluated average organ doses and effective doses in 2,411 pediatric patients due to diagnostic procedures with radiopharmaceuticals. For 1 year, effective doses were greater than literature. For 5 years, differences were noticed between present work and literature for bone scintigraphy, thyroid scintigraphy and 67Ga citrate scintigraphy. These differences may be attributed to the uncertainties in internal dose calculations. High absorved doses in bone surfaces of children due to 67Ga citrate and bone scintigraphy should be evaluated accordingly. Current protocols used recommend standardized...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pediatrics; Oncology; Dosimetry; Radiopharmaceuticals; Nuclear medicine; Radiation protection.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700019
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Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc BABT
Dantas,Bernardo Maranhão; Dantas,Ana Letícia Almeida; Marques,Fábio Luiz Navarro; Bertelli,Luiz; Stabin,Michael G..
99mTc is a radionuclide widely used for imaging diagnosis in nuclear medicine. In Brazil it is obtained by elution from 99Mo-99mTc generators supplied by the Nuclear Energy Research Institute (IPEN). The elution is carried out in radiopharmacy laboratories located in hospitals and clinics. Depending of the quality of the generator and conditions of use during the elution process, 99Mo can be extracted from the column of the generator, becoming a radionuclidic impurity of the eluate used for the obtention of the radiopharmaceutical to be administered to the patient. 99Mo emits high-energy photons and beta particles and its presence degrades the quality of the image and unnecessarily increases the radiation dose delivered to the patient. An in-vivo...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Molybdenum 99; Technetium 99m; Nuclear medicine; Internal dosimetry; In vivo measurements; Whole body counter.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700032
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Guidance for nuclear medicine staff on radiopharmaceuticals drug interaction BJPS
Santos-Oliveira,Ralph.
Numerous drug interactions related to radiopharmaceuticals take place every day in hospitals many of which are not reported or detected. Information concerning this kind of reaction is not abundant, and nuclear medicine staff are usually overwhelmed by this information. To better understand this type of reaction, and to help nuclear medicine staff deal with it, a review of the literature was conducted. The results show that almost all of radiopharmaceuticals marketed around the world present drug interactions with a large variety of compounds. This suggests that a logical framework to make decisions based on reviews incorporating adverse reactions must be created. The review also showed that researchers undertaking a review of literature, or even a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nuclear medicine; Radiology; Radiopharmaceuticals/drug interaction; Molecular imaging.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400003
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Influence of radiation on endotoxin test using the PTS TM for 18-FDG radiopharmaceutical BJPS
Santos-Oliveira,Ralph.
F-18 FDG (2-[18-F] fluoro-2-deoxy-D-glucose) is the most frequently used radiopharmaceutical for PET and PET CT imaging exams. The FDA recently approved the use of the PTS TM (Portable Test System) as an alternative to the standard test proposed by the United States Pharmacopeia using the LAL (Limulus Amebocyte Lysates), that takes longer to perform (about 1h) than the PTS TM (15 min). Recent studies have demonstrated that radiation could interfere with the PTS TM test. In order to study the effects of radiation on the PTS TM test and/or equipment, 27 batches of F-18 FDG produced in the Nuclear Engineering Institute were analyzed. The results showed that no direct correlation with radiation was found in any of the cases.
Tipo: Info:eu-repo/semantics/article Palavras-chave: 18-FDG/utilization; Radiopharmaceuticals; Nuclear medicine; Endotoxin test; Portable Test System/radiation effects.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300019
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Internal exposure in nuclear medicine: application of IAEA criteria to determine the need for internal monitoring BABT
Dantas,Bernardo Maranhão; Lucena,Eder Augusto de; Dantas,Ana Letícia Almeida.
The manipulation of unsealed sources in nuclear medicine poses significant risks of internal exposure to the staff. According to the International Atomic Energy Agency, the radiological protection program should include an evaluation of such risks and an individual monitoring plan, assuring acceptable radiological safety conditions in the workplace. The IAEA Safety Guide RS-G-1.2 recommends that occupational monitoring should be implemented whenever it is likely that committed effective doses from annual intakes of radionuclides would exceed 1 mSv. It also suggests a mathematical criterion to determine the need to implement internal monitoring. This paper presents a simulation of the IAEA criteria applied to commonly used radionuclides in nuclear medicine,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nuclear medicine; Internal monitoring; Radiation protection.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700017
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Nuclear medicine imaging technique in the erectile dysfunction evaluation: a mini-review BABT
Ribeiro,Camila Godinho; Moura,Regina; Neves,Rosane de Figueiredo; Spinosa,Jean Pierre; Bernardo-Filho,Mario.
Functional imaging with positron emission tomography and single photon emission computed tomography is capable of visualizing subtle changes in physiological function in vivo. Erectile dysfunction(ED) diminishes quality of life for affected men and their partners. Identification of neural substrates may provide information regarding the pathophysiology of types of sexual dysfunction originating in the brain. The aim of this work is to verify the approaches of the nuclear medicine techniques in the evaluation of the erectile function/disfunction. A search using the words ED and nuclear medicine, ED and scintigraphy, ED and spect and ED and pet was done in the PubMed. The number of citations in each subject was determined. Neuroimaging techniques offer...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nuclear medicine; Erectile dysfunction; Positron emission tomography; Single photon emission computed tomography.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600010
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Nuclear medicine in tropical diseases BABT
Braga,Francisco José Hossri Nogueira.
Tropical diseases affect more people in the world than any other kind of disease, but scintigraphic data on that matter are not so frequent in the literature. Since the geographic regions where such diseases occur are normally very poor, scintillation cameras may not be available. We present a resumed summary of part of what has been done on this subject to-date. Leprosy affects circa 12 million people worldwide and has already been studied by means of the following scintigraphic exams: Gallium-67, 99mTc-MDP or HMDP, 99mTc-colloid or Dextran, 99mTc-DTPA and 99mTc-WBC. Paracoccidiodomycosis is a deep mycosis and such cases may be evaluated by means of Gallium-67, bone scintigraphy, lymphoscintigraphy, hepato-billiary, bone marrow and liver / spleen...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nuclear medicine; Scintigraphy; Tropical diseases; Leprosy; Paracoccidioidomycosis; Blastomycosis; Mucormycosis; Tuberculosis; Neurocysticercosis; Cutaneous and mucous leishmaniasis; Chagas’ disease.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500002
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Nuclear medicine methods in the assessment of acupuncture effects: a short review BABT
Souza,Deise Elisabete; Rebello,Bernardo Machado; Silva Filho,Reginaldo de Carvalho; Agostinho,Raquel Terra; Bastos,Sohaku R. C.; Bernardo-Filho,Mario.
The mechanisms of acupuncture are poorly understood. In consequence, numerous investigators have conducted clinical trials to test the efficacy of acupuncture in various conditions. We have used PubMed database system to evaluate the number of publications in acupuncture and nuclear medicine procedures in the period from 1964 to 2007, using the keywords: "nuclear medicine and acupuncture", "SPECT and acupuncture", "PET and acupuncture", "scintigraphy and acupuncture", "radionuclide and acupuncture", "radiopharmaceutical and acupuncture", "radioisotope and acupuncture" and "99mTc and acupuncture". Some papers published in English language were selected and a short review is presented The analysis of the number of publications shows that when a method is...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acupuncture; Nuclear medicine; Traditional Chinese Medicine.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600012
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Tc-99m direct radiolabeling of monoclonal antibody ior egf/r3: quality control and image studies in mice BABT
Dias,Carla Roberta; Marczewski,Barbara; Moraes,Vanessa; Barboza,Marycel Figols de; Osso Junior,João Alberto.
Monoclonal antibodies (Mabs) have been useful for immunoscintigraphic applications in clinical diagnosis since they were introduced in the practice of nuclear medicine. The ior egf/r3 (Centis, Cuba) is a murine monoclonal antibody against epidermal growth factor receptor (EGF-R) and has been widely used in the radioimmunodiagnosis of tumors of epithelial origin. Labeled with 99mTc, its main application in Nuclear Medicine is the follow up, detection and evaluation of tumor recurrences. The objective of this work is to describe the preparation of a lyophilized formulation (kit) for radiolabeling the Mab ior egf/r3 with 99mTc for immunoscintigraphic applications. Radiolabeling efficiency, effects on immunoreactivity, image studies and stability of the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Radiolabeling; Technetium; Monoclonal antibodies; Nuclear medicine.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700004
Registros recuperados: 9
Primeira ... 1 ... Última
 

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