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	Provedor de dados BJMBR (2) Autor Blatt,S.L. (1) Takahashi,R.N. (1) Palavra-chave Plus-maze (2) Animal models of anxiety (1) Anxiety (1) Behavioural profiling (1) Defence (1) Ethanol (1) Ethology (1) Pharmacology (1) Place preference (1) Risk assessment (1) Wistar rats (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 1999 (1) 1997 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Animal models of anxiety: an ethological perspective BJMBR In the field of anxiety research, animal models are used as screening tools in the search for compounds with therapeutic potential and as simulations for research on mechanisms underlying emotional behaviour. However, a solely pharmacological approach to the validation of such tests has resulted in distinct problems with their applicability to systems other than those involving the benzodiazepine/GABAA receptor complex. In this context, recent developments in our understanding of mammalian defensive behaviour have not only prompted the development of new models but also attempts to refine existing ones. The present review focuses on the application of ethological techniques to one of the most widely used animal models of anxiety, the elevated plus-maze... Tipo: Info:eu-repo/semantics/other Palavras-chave: Animal models of anxiety; Ethology; Defence; Risk assessment; Plus-maze; Behavioural profiling; Pharmacology. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000300002 Experimental anxiety and the reinforcing effects of ethanol in rats BJMBR Blatt,S.L.; Takahashi,R.N.. In order to examine the relationship between anxiety and reinforcing effects of alcohol, drug-naive male Wistar rats weighing 250-300 g were classified as "anxious" and "non-anxious" in the elevated plus-maze test. A conditioned place preference test was then used to investigate the reinforcing effects of ethanol (EtOH) on these animals. On 2 alternate days, groups of "anxious", "non-anxious" and "normal" rats received intraperitoneal (ip) injections of EtOH (0.5, 1.0 or 1.5 g/kg) immediately before a 15-min confinement to the white compartment. On the 2 intervening days the same rats received ip injections of saline before confinement to the opposite compartment. On day 5, a 15-min free-choice test was carried out with no injections. Rats classified as... Tipo: Info:eu-repo/semantics/article Palavras-chave: Anxiety; Plus-maze; Place preference; Ethanol; Wistar rats. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000400013 Registros recuperados: 2 Primeira ... 1 ... Última

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