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	Provedor de dados BJMBR (2) Autor Krieger,E.M. (2) Moreira,E.D. (2) Cestari,I.A. (1) Farah,V.M.A. (1) Irigoyen,M.C. (1) Silva,G.J.J. (1) Trindade Jr.,A.S. (1) Ushizima,M. (1) Mais... Palavra-chave Renal hypertension (2) Angiotensin II (1) Aortic depressor nerve (1) Arterial baroreceptor (1) Baroreflex sensitivity (1) Electrical stimul (1) Losartan (1) Sinoaortic denervation (1) Mais... Tipo do documento Info:eu-repo/semantics/other (2) Ano 2009 (1) 2000 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Acute AT1 receptor blockade does not improve the depressed baroreflex in rats with chronic renal hypertension BJMBR Farah,V.M.A.; Moreira,E.D.; Ushizima,M.; Cestari,I.A.; Irigoyen,M.C.; Krieger,E.M.. To assess the role of angiotensin II in the sensitivity of the baroreflex control of heart rate (HR) in normotensive rats (N = 6) and chronically hypertensive rats (1K1C, 2 months, N = 7), reflex changes of HR were evaluated before and after (15 min) the administration of a selective angiotensin II receptor antagonist (losartan, 10 mg/kg, iv). Baseline values of mean arterial pressure (MAP) were higher in hypertensive rats (195 ± 6 mmHg) than in normotensive rats (110 ± 2 mmHg). Losartan administration promoted a decrease in MAP only in hypertensive rats (16%), with no changes in HR. During the control period, the sensitivity of the bradycardic and tachycardic responses to acute MAP changes were depressed in hypertensive rats (~70% and ~65%, respectively)... Tipo: Info:eu-repo/semantics/other Palavras-chave: Baroreflex sensitivity; Losartan; Angiotensin II; Renal hypertension. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001200014 Evidence that blood pressure remains under the control of arterial baroreceptors in renal hypertensive rats BJMBR Trindade Jr.,A.S.; Moreira,E.D.; Silva,G.J.J.; Krieger,E.M.. The purpose of the present study was to determine the range of the influence of the baroreflex on blood pressure in chronic renal hypertensive rats. Supramaximal electrical stimulation of the aortic depressor nerve and section of the baroreceptor nerves (sinoaortic denervation) were used to obtain a global analysis of the baroreceptor-sympathetic reflex in normotensive control and in chronic (2 months) 1-kidney, 1-clip hypertensive rats. The fall in blood pressure produced by electrical baroreceptor stimulation was greater in renal hypertensive rats than in normotensive controls (right nerve: -47 ± 8 vs -23 ± 4 mmHg; left nerve: -51 ± 7 vs -30 ± 4 mmHg; and both right and left nerves: -50 ± 8 vs -30 ± 4 mmHg; P < 0.05). Furthermore, the increase in... Tipo: Info:eu-repo/semantics/other Palavras-chave: Arterial baroreceptor; Renal hypertension; Sinoaortic denervation; Aortic depressor nerve; Electrical stimul. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001000013 Registros recuperados: 2 Primeira ... 1 ... Última

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