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	Provedor de dados BJMBR (3) Autor Azambuja,M.I (1) Benjamin,A.C.W. (1) Diniz,E.M.A. (1) Hoffmann,J.W. (1) Lyra,P.P.R. (1) Moreira,P.E. (1) Procianoy,R.S. (1) Silveira,R.C. (1) Vaz,F.A.C. (1) de Mello,D.E. (1) Mais... Palavra-chave Respiratory distress syndrome (3) Autoimmunity (1) Coronary disease (1) Disease outbreaks (1) Disease susceptibility (1) Endothelin-1 (1) Hyaline membrane disease (1) Influenza (1) Polymorphisms (1) Prematurity (1) Pulmonary hypertension (1) SNAPPE II (1) Surfactant protein B (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Info:eu-repo/semantics/other (1) Ano 2008 (1) 2007 (1) 2005 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Comparison of surfactant protein B polymorphisms of healthy term newborns with preterm newborns having respiratory distress syndrome BJMBR Lyra,P.P.R.; Vaz,F.A.C.; Moreira,P.E.; Hoffmann,J.W.; de Mello,D.E.; Diniz,E.M.A.. Polymorphisms and mutations in the surfactant protein B (SP-B) gene have been associated with the pathogenesis of respiratory distress syndrome (RDS). The objective of the present study was to compare the frequencies of SP-B gene polymorphisms between preterm babies with RDS and healthy term newborns. We studied 50 preterm babies with RDS (inclusion criteria - newborns with RDS and gestational age between 28 and 33 weeks and 6 days), and 100 healthy term newborns. Four SP-B gene polymorphisms were analyzed: A/C at nucleotide -18, C/T at nucleotide 1580, A/G at nucleotide 9306, and G/C at nucleotide 8714, by PCR amplification of genomic DNA and genotyping by cRFLP. The healthy newborns comprised 42 female and 58 male neonates; 39 were white and 61... Tipo: Info:eu-repo/semantics/article Palavras-chave: Polymorphisms; Surfactant protein B; Respiratory distress syndrome. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000600005 Connections: can the 20th century coronary heart disease epidemic reveal something about the 1918 influenza lethality? BJMBR Azambuja,M.I. This essay proposes that the ecologic association shown between the 20th century coronary heart disease epidemic and the 1918 influenza pandemic could shed light on the mechanism associated with the high lethality of the latter. It suggests that an autoimmune interference at the apoB-LDL interface could explain both hypercholesterolemia and inflammation (through interference with the cellular metabolism of arachidonic acid). Autoimmune inflammation, then, would explain the 1950s-60s acute coronary events (coronary thrombosis upon influenza re-infection) and the respiratory failure seen among young adults in 1918. This hypothesis also argues that the lethality of the 1918 pandemic may have not depended so much on the 1918 virus as on an immune vulnerability... Tipo: Info:eu-repo/semantics/other Palavras-chave: Respiratory distress syndrome; Autoimmunity; Influenza; Coronary disease; Disease susceptibility; Disease outbreaks. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000100001 Umbilical cord blood and neonatal endothelin-1 levels in preterm newborns with and without respiratory distress syndrome BJMBR Benjamin,A.C.W.; Silveira,R.C.; Procianoy,R.S.. Increased pulmonary vascular resistance in preterm newborn infants with respiratory distress syndrome is suggested, and endothelin-1 plays an important role in pulmonary vascular reactivity in newborns. We determined umbilical cord blood and neonatal (second sample) levels of endothelin-1 in 18 preterm newborns with respiratory distress syndrome who had no clinical or echocardiographic diagnosis of pulmonary hypertension and 22 without respiratory distress syndrome (gestational ages: 31.4 ± 1.6 and 29.3 ± 2.3 weeks, respectively). Umbilical cord blood and a second blood sample taken 18 to 40 h after birth were used for endothelin-1 determination by enzyme immunoassay. Median umbilical cord blood endothelin-1 levels were similar in both groups (control:... Tipo: Info:eu-repo/semantics/article Palavras-chave: Endothelin-1; Respiratory distress syndrome; Prematurity; Hyaline membrane disease; Pulmonary hypertension; SNAPPE II. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000900017 Registros recuperados: 3 Primeira ... 1 ... Última

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