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Rodríguez-Martínez,M.; Torres-Rodríguez,M.L.; Brito-Orta,M.D.; López-Rodriguez,J.F.; Rodríguez-Pérez,A.S.; Calvo-Turrubiartes,M.Z.; Llamazares-Azuara,L.. |
There is no index or criterion of aortic barodenervation, nor can we differentiate among rats that have suffered chronic sham, aortic or sino-aortic denervation. The objective of this study was to develop a procedure to generate at least one quantitative, reproducible and validated index that precisely evaluates the extent of chronic arterial barodenervation performed in conscious rats. Data from 79 conscious male Wistar rats of about 65-70 days of age with diverse extents of chronic arterial barodenervation and used in previous experiments were reanalyzed. The mean arterial pressure (MAP) and the heart rate (HR) of all rats were measured systematically before (over 1 h) and after three consecutive iv bolus injections of phenylephrine (PHE) and sodium... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aortic denervation; Sinoaortic denervation; Effectiveness of barodenervation. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001100008 |
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