Sabiia Seb
PortuguêsEspañolEnglish
Embrapa
        Busca avançada

Botão Atualizar


Botão Atualizar

Ordenar por: 

RelevânciaAutorTítuloAnoImprime registros no formato resumido
Registros recuperados: 26
Primeira ... 12 ... Última
Imagem não selecionada

Imprime registro no formato completo
A Feedback Mechanism to Control Apoptosis Occurs in the Digestive Gland of the Oyster Crassostrea gigas Exposed to the Paralytic Shellfish Toxins Producer Alexandrium catenella ArchiMer
Rolland, Jean-luc; Medhioub, Walid; Vergnes, Agnes; Abi-khalil, Celina; Savar, Veronique; Abadie, Eric; Masseret, Estelle; Amzil, Zouher; Laabir, Mohamed.
To better understand the effect of Paralytic Shellfish Toxins (PSTs) accumulation in the digestive gland of the Pacific oyster, Crassostrea gigas, we experimentally exposed individual oysters for 48 h to a PSTs producer, the dinoflagellate Alexandrium catenella. In comparison to the effect of the non-toxic Alexandrium tamarense, on the eight apoptotic related genes tested, Bax and BI.1 were significantly upregulated in oysters exposed 48 h to A. catenella. Among the five detoxification related genes tested, the expression of cytochrome P450 (CYP1A) was shown to be correlated with toxin concentration in the digestive gland of oysters exposed to the toxic dinoflagellate. Beside this, we observed a significant increase in ROS production, a decrease in...
Tipo: Text Palavras-chave: Shellfish; Toxin; Biomarker; Expression; Phytoplankton.
Ano: 2014 URL: http://archimer.ifremer.fr/doc/00225/33606/32003.pdf
Imagem não selecionada

Imprime registro no formato completo
A sensitive bioassay for destruxins, cyclodepsipeptides from the culture filtrates of the entomopathogenic fungus Metarhizium anisopliae (Metsch.) Sorok. Anais da SEB
Samuels,Richard I..
Destruxin A, a toxic cyclodepsipeptide, was purified from culture filtrates of the entomopathogenic fungus Metarhizium anisopliae (Metsch.) Sorok. by Reverse-Phase HPLC, and assayed for its effects on a larval Manduca sexta (L.) (Lepidoptera: Sphingidae) heart preparation. Destruxin A was found to cause reversible and dose-dependent acceleration of the heart beat. The heart bioassay was highly sensitive to pulse applications of destruxin A at concentrations as low as 35 pmol. Because of its high level of sensitivity, the M. sexta heart bioassay could be used to detect and quantify destruxins in tissue extracts from mycosed insects or to confirm bioactivity of HPLC fractions. The site of action of Destruxin A was not determined. However, this toxin did not...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Insecta; Manduca sexta; Heart; Toxin; Peptide; Destruxin.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0301-80591998000200009
Imagem não selecionada

Imprime registro no formato completo
Anticancer potential of nanogold conjugated toxin GNP-NN-32 from Naja naja venom J. Venom. Anim. Toxins incl. Trop. Dis.
Attarde,Saurabh S.; Pandit,Sangeeta V..
Abstract Background: Cancer is the second most common fatal disease in the world, behind cardiovascular disorders in the first place. It accounts for around 0.3 million deaths per year in India due to the lack of proper diagnostic facilities, prevention and treatment. Current therapeutic methods do not provide adequate protection and affect normal cells along with cancerous ones. Thus, there is a need for some alternative therapeutic strategy, preferably from natural products, which have been traditionally used for treatment of various diseases in the country. Methods: In this study, we have conjugated purified NN-32 toxin from Naja naja venom with gold nanoparticles and its anticancer potential was evaluated against human breast cancer cell lines....
Tipo: Info:eu-repo/semantics/article Palavras-chave: GNP-NN-32; Anticancer; Toxin; Naja naja; Venom; Breast cancer; MCF-7; MDA-MB-231.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100304
Imagem não selecionada

Imprime registro no formato completo
Biodistribution studies of bee venom and spider toxin using radiotracers J. Venom. Anim. Toxins incl. Trop. Dis.
Yonamine,C. M.; Costa,H.; Silva,J. A. A.; Muramoto,E.; Rogero,J. R.; Troncone,L. R. P.; Camillo,M. A. P..
The use of radiotracers allows the understanding of the bioavailability process, biodistribution, and kinetics of any molecule labelled with an isotope, which does not alter the molecule's biological properties. In this work, technetium-99m and iodine-125 were chosen as radiotracers for biodistribution studies in mice using bee (Apis mellifera) venom and a toxin (PnTX2-6) from the Brazilian "armed" spider (Phoneutria nigriventer) venom. Incorporated radioactivity was measured in the blood, brain, heart, lung, liver, kidney, adrenal gland, spleen, stomach, testicle, intestine, muscle, and thyroid gland. Results provided the blood kinetic parameter, and different organs distribution rates.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Phoneutria nigriventer; Apis mellifera; Toxin; Venom; Radiotracer; Biodistribution.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000100006
Imagem não selecionada

Imprime registro no formato completo
Characterization of Leiurus abdullahbayrami (Scorpiones: Buthidae) venom: peptide profile, cytotoxicity and antimicrobial activity J. Venom. Anim. Toxins incl. Trop. Dis.
Erdeş,Efe; Doğan,Tuğba Somay; Coşar,İlhan; Danışman,Tarık; Kunt,Kadir Boğaç; Şeker,Tamay; Yücel,Meral; Özen,Can.
Background Scorpion venoms are rich bioactive peptide libraries that offer promising molecules that may lead to the discovery and development of new drugs.Leiurus abdullahbayrami produces one of the most potent venoms among Turkish scorpions that provokes severe symptoms in envenomated victims.Methods In the present study, the peptide profile of the venom was investigated by electrophoretic methods, size-exclusion and reversed-phase chromatography and mass spectroscopy. Cytotoxic and antimicrobial effects were evaluated on a breast cancer cell line (MCF-7) and various bacterial and fungal species.Results Proteins make up approximately half of the dry weight of L. abdullahbayrami crude venom. Microfluidic capillary electrophoresis indicated the presence of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion venom; Toxin; Peptide; Leiurus abdullahbayrami; Microfluidic capillary; Electrophoresis; Peptidomics; Venomics; Cytotoxicity; Antimicrobial activity; Turkey.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200338
Imagem não selecionada

Imprime registro no formato completo
Cyanobacteria, microcystins and cylindrospermopsin in public drinking supply reservoirs of Brazil Anais da ABC (AABC)
BITTENCOURT-OLIVEIRA,MARIA DO CARMO; PICCIN-SANTOS,VIVIANE; MOURA,ARIADNE N.; ARAGÃO-TAVARES,NÍSIA K.C.; CORDEIRO-ARAÚJO,MICHELINE K..
Brazil has a history of blooms and contamination of freshwater systems by cyanobacterial toxins. The monitoring relevance of toxins from cyanobacteria in reservoirs for public supply is notorious given its high toxicity to mammals, included humans beings. The most recurrent toxins in Brazilian water bodies are microcystins (MC). However, the recent record of cylindrospermopsin (CYN) in northeastern Brazil, Pernambuco state, alerts us to the possibility that this could be escalating. This study reports occurrence of MC and CYN, quantified with ELISA, in 10 reservoirs, devoted to public drinking supply in northeastern Brazil. The composition and quantification of the cyanobacteria community associated with these water bodies is also presented. From 23...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bloom; Harmful algae; Monitoring; Toxin; Water quality.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000100297
Imagem não selecionada

Imprime registro no formato completo
Fitness cost of resistance to Bacillus thuringiensis in velvetbean caterpillar Anticarsia gemmatalis Hübner (Lepidoptera, Noctuidae) Rev. Bras. entomol.
Sosa-Gómez,Daniel Ricardo; Miranda,José Ednilson.
Selection pressure to obtain resistant genotypes can result in fitness cost. In this study, we report the effects of the selection pressure of a commercial formulation of Bacillus thuringiensis on biological aspects of a Dipel-resistant strain of velvetbean caterpillar, Anticarsia gemmatalis Hübner. Comparisons of Dipel-resistant and susceptible individuals revealed significant differences in pupal weight and larval development time. Both strains (Dipel-resistant and susceptible) were susceptible to Cry1Ac toxin expressed in foliar cotton tissues. Resistant and susceptible strains showed low survival rates of 22.5% and 51.2%, respectively, when fed with Greene diet containing Bt-cotton. Larvae bioassayed after three laboratory generations presented lower...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anticarsia gemmatalis; Toxin; Cry1Ac; Dipel-resistant; Strain.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262012000300014
Imagem não selecionada

Imprime registro no formato completo
Heterologous expression, protein folding and antibody recognition of a neurotoxin from the Mexican coral snake Micrurus laticorallis J. Venom. Anim. Toxins incl. Trop. Dis.
Clement,Herlinda; Flores,Vianey; la Rosa,Guillermo De; Zamudio,Fernando; Alagon,Alejandro; Corzo,Gerardo.
Abstract Background The cysteine-rich neurotoxins from elapid venoms are primarily responsible for human and animal envenomation; however, their low concentration in the venom may hamper the production of efficient elapid antivenoms. Therefore, the aim of the present study was to produce fully active elapid neurotoxic immunogens for elapid antivenom production. Method Cysteine-rich neurotoxins showed recombinant expression in two strains of E. coli, and were purified using affinity chromatography and reverse-phase HPLC (rpHPLC). Results The cDNA of the four disulfide-bridged peptide neurotoxin Mlat1 was cloned into a modified expression vector, pQE30, which was transfected into two different E. coli strains. The recombinant toxin (HisrMlat1) was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Micrurus laticorallis; Protein folding; Recombinant; Elapid; Toxin; Protein recognition.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100318
Imagem não selecionada

Imprime registro no formato completo
Idenfication of a novel storage glycine-rich peptide from guava (Psidium guajava) seeds with activity against Gram-negative bacteria. Repositório Alice
PELEGRINI, P. B.; MURAD, A. M.; SILVA, L. P.; SANTOS, R. C. P. dos; COSTA, F. T.; TAGLIARI, P. D.; BLOCH JÚNIOR, C.; NORONHA, E. F.; MILLER, R. N. G.; FRANCO, O. L..
Tipo: Artigo de periódico Palavras-chave: Toxin; Glycine-rich proteins; Proteína; Psidium Guajava; Toxina; Antimicrobial peptides.
Ano: 2008 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/190360
Imagem não selecionada

Imprime registro no formato completo
Influencia da temperatura de cultivo no crescimento e producao e toxicidade do isolado S93 de Bacillus thuringiensis subesp. kurstaki. Repositório Alice
GIUSTI, J. S.; COSTA, D. C.; DIAS, J. M. C. S..
Tipo: Anais e Proceedings de eventos Palavras-chave: Cultivo; Toxin; Culture.; Bacillus Thuringiensis; Toxina; Temperatura.; Temperature..
Ano: 1996 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/171476
Imagem não selecionada

Imprime registro no formato completo
Investigation of mad honey use as an alternative treatment in patients admitted to the pulmonary clinic: Ordu, Turkey example BABT
Ugur,Hacer Gok; Sıralı,Recep; Tekgul,Ahmet Talha; Efe,Burcin.
Abstract This study assessed mad honey use in alternative treatments. The universe of this descriptive study was patients admitted to the pulmonary disease clinic located in the Ordu province of the Black Sea region between 15 December 2014 and 15 February 2015. We did not use a sampling method and patients who agreed to participate were included in the study (n=353). In order to collect the data, we used a questionnaire prepared by the researchers. In this study, 77% of the participants stated that mad honey was beneficial to health, 44.5% used mad honey, and 53.5% consumed it daily. Furthermore, 28.7% used mad honey for asthma, 6.4% for cough, 12.1% for gastrointestinal diseases, and 3.2% for hypertension. There was a significant relationship between the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mad honey; Health; Alternative treatment; Toxin; Poisoning.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100310
Imagem não selecionada

Imprime registro no formato completo
Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin BJM
Alves,Guilherme Guerra; Machado-de-Ávila,Ricardo Andrez; Chávez-Olórtegui,Carlos Delfin; Silva,Rodrigo Otávio Silveira; Lobato,Francisco Carlos Faria.
Abstract The epsilon toxin, produced by Clostridium perfringens, is responsible for enterotoxemia in ruminants and is a potential bioterrorism agent. In the present study, 15 regions of the toxin were recognized by antibodies present in the serum, with different immunodominance scales, and may be antigen determinants that can be used to formulate subunit vaccines.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Epsilon; Toxin; Enterotoxemia; Epitope; Mapping.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000300570
Imagem não selecionada

Imprime registro no formato completo
Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum. Repositório Alice
SCHWARTZ, E. F.; CAMARGOS, T. S.; ZAMUDIO, R. Z.; SILVA, L. P.; BLOCH JÚNIOR, C.; CAIXETA, F.; SCHWARTZ, C. A.; POSSANI, L. D..
Tipo: Artigo de periódico Palavras-chave: Opisthacanthus cayaporum; Antimicrobial agent; Lon Channel; Phospolipase; Scorpion; Toxin; Escorpião; Toxina; Mass spectrometry.
Ano: 2008 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/190351
Imagem não selecionada

Imprime registro no formato completo
New parasitism record of Pyemotes tritici (LaGreze-Fossat e Montagne, 1851) (Acari: Pyemotidae) on boll weevils inside cotton squares. Repositório Alice
SILVA, C. A. D. da; MORAES, G. J. de; CASTILHO, R. C.; RAMALHO, F. S.; LIMA, T. A..
Mites of the family Pyemotidae are reported as ectoparasites of a large number of arthropods He et al., 2019; Sousa et al., 2020; Chen et al. 2021), mainly insects of the orders Lepidoptera (Cunha et al., 2006; Oliveira et al., 2007; He et al. 2012, 2014; Liu et al, 2020; Tian et al. 2020), Hemiptera (Han, 2016; Li et al. 2019; Yu et al. 2019), and Coleoptera (Cunha et al. 2006; Guo et al. 2009; Oliveira et al., 2010). Pyemotes spp., also known as ?straw itch mites?, are of particular interest in applied acarology, both for their behavior as insect parasites and for their medical importance (Tomczyk-Socha et al. 2017; He et al., 2019). Adult females of this mite attach themselves to the host to feed, undergoing physogastry, the expansion of the posterior...
Tipo: Artigo de periódico Palavras-chave: Toxin; Artrópodes; Ácaro da palha; Algodão; Ácaro; Toxina; Parasitismo; Anthonomus Grandis; Anthonomus grandis grandis; Dust mites; Parasitism; Cotton.
Ano: 2022 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1146824
Imagem não selecionada

Imprime registro no formato completo
Paralytic shellfish poison outbreaks in the Penze estuary: Environmental factors affecting toxin uptake in the oyster, Crassostrea gigas ArchiMer
Lassus, Patrick; Baron, Regis; Garen, Pierre; Truquet, Philippe; Masselin, Pierre; Bardouil, Michele; Leguay, Didier; Amzil, Zouher.
Several experiments using a self-regulated system were conducted to define the factors likely to influence the uptake of paralytic shellfish poison (PSP) by oysters in the Penze estuary (France, Brittany). Each 4-day experiment was carried out in a recirculated sea water system using 15 Pacific oysters (Crassostrea gigas) separated from each other and supplied with unfiltered natural seawater containing alternatively toxic (Alexandrium minutum) or non-toxic (Skeletonema costatum) algal diets. The food supply and exposure times to toxic diets were determined according to field studies of the Upstream and downstream movement of patches containing A. minutum. The experimental parameters corresponded roughly to the hydrological conditions generally observed in...
Tipo: Text Palavras-chave: Experimental contamination; Oyster toxicity; Dinophyceae; Toxin; PSP.
Ano: 2004 URL: http://archimer.ifremer.fr/doc/2004/publication-400.pdf
Imagem não selecionada

Imprime registro no formato completo
Phycotoxin monitoring in France : risk-based strategy and main results (2006-2008) ArchiMer
Belin, Catherine; Amzil, Zouher.
Toxin monitoring is carried out along the coasts of France by a national network, REPHY, which is the National Monitoring Network for Phytoplankton and Phycotoxins. Sampling strategy differs according to the type of zone coastal or offshore and to the family of toxins. For PSP and ASP toxins, monitoring is based on the detection of toxic phytoplankton species. For lipophilic toxins, a systematic analysis of toxins is performed in risk areas during high risk periods. Experimental monitoring for palytoxins has also been conducted along the Mediterranean coast since 2007. The total number of toxin analyses is in the order of 2500 to 3000 per year. The detailed results for each family of toxins showed that the most frequent toxic events for the period from...
Tipo: Text Palavras-chave: Monitoring; Phytoplankton; Toxin; Sampling; Shellfish; French coasts.
Ano: 2010 URL: http://archimer.ifremer.fr/doc/00077/18821/16398.pdf
Imagem não selecionada

Imprime registro no formato completo
Production of zearalenone by Fusarium spp. in maize kernel Thai Agricultural
Chintana Chana; Pranee Hamelink; Chiradej Chamswarng; Ronnapop Bunjoedchoedchu.
2 tables
Palavras-chave: Corn; Maize; Fungi; Fusarium spp.; Toxin; Zearalenone; ข้าวโพด; การสร้างเซียราลีโนน; ฟูซาเรียม.
Ano: 1989 URL: http://anchan.lib.ku.ac.th/agnet/handle/001/4369
Imagem não selecionada

Imprime registro no formato completo
PURIFICATION AND CHARACTERIZATION OF TOXINS FROM WHEAT ISOLATES OF Drechslera tritici-repentis, Bipolaris bicolor, AND Bipolaris sorokiniana J. Venom. Anim. Toxins
BACH,E. E.; KIMATI,H..
Low molecular weight metabolites produced by Bipolaris bicolor, Bipolaris sorokiniana, and Drechslera tritici-repentis are considered to be toxins that facilitate disease in wheat cultivars. Several such toxins were isolated from these fungi. Electrophoresis demonstrated bands of proteins that reduced shoot inhibition in susceptible plants but not in resistant plants. Chlorophyll content was reduced during the first 10 hours of light in the susceptible plants and after 18 hours in the resistant plants. The enzyme beta-1,3-glucanase increased in the resistant plants after treatment with toxins, but in the susceptible plants this enzyme decreased compared to the control. This suggests that the toxin was a protein and the susceptible plants needed other...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Toxin; Wheat pathogens; Protein toxin.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301999000200006
Imagem não selecionada

Imprime registro no formato completo
Skin secretion of Siphonops paulensis (Gymnophiona, Amphibia) forms voltage-dependent ionic channels in lipid membranes BJMBR
Schwartz,E.F.; Stucchi-Zucchi,A.; Schwartz,C.A.; Salomão,L.C..
The effect of the skin secretion of the amphibian Siphonops paulensis was investigated by monitoring the changes in conductance of an artificial planar lipid bilayer. Skin secretion was obtained by exposure of the animals to ether-saturated air, and then rinsing the animals with distilled water. Artificial lipid bilayers were obtained by spreading a solution of azolectin over an aperture of a Delrin cup inserted into a cut-away polyvinyl chloride block. In 9 of 12 experiments, the addition of the skin secretion to lipid bilayers displayed voltage-dependent channels with average unitary conductance of 258 ± 41.67 pS, rather than nonspecific changes in bilayer conductance. These channels were not sensitive to...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Siphonops; Toxin; Channel-forming toxins; Skin secretion; Ion channel; Hemolysin.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000900020
Imagem não selecionada

Imprime registro no formato completo
Species-specific mechanisms of cytotoxicity toward immune cells determine the successful outcome of Vibrio infections ArchiMer
Rubio, Tristan; Oyanedel, Daniel; Labreuche, Yannick; Toulza, Eve; Luo, Xing; Bruto, Maxime; Chaparro, Cristian; Torres, Marta; De Lorgeril, Julien; Haffner, Philippe; Vidal-dupiol, Jeremie; Lagorce, Arnaud; Petton, Bruno; Mitta, Guillaume; Jacq, Annick; Le Roux, Frederique; Charriere, Guillaume; Destoumieux-garzon, Delphine.
Vibrio species cause infectious diseases in humans and animals, but they can also live as commensals within their host tissues. How Vibrio subverts the host defenses to mount a successful infection remains poorly understood, and this knowledge is critical for predicting and managing disease. Here, we have investigated the cellular and molecular mechanisms underpinning infection and colonization of 2 virulent Vibrio species in an ecologically relevant host model, oyster, to study interactions with marine Vibrio species. All Vibrio strains were recognized by the immune system, but only nonvirulent strains were controlled. We showed that virulent strains were cytotoxic to hemocytes, oyster immune cells. By analyzing host and bacterial transcriptional...
Tipo: Text Palavras-chave: T6SS; Toxin; Dual RNA-seq; Cytolysis; Pathogenesis.
Ano: 2019 URL: https://archimer.ifremer.fr/doc/00507/61837/65900.pdf
Registros recuperados: 26
Primeira ... 12 ... Última
 

Empresa Brasileira de Pesquisa Agropecuária - Embrapa
Todos os direitos reservados, conforme Lei n° 9.610
Política de Privacidade
Área restrita

Embrapa
Parque Estação Biológica - PqEB s/n°
Brasília, DF - Brasil - CEP 70770-901
Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco

Valid HTML 4.01 Transitional