Data/hora: 05/06/2024 06:45:48

Provedor de dados: | 17
País: | United Kingdom
Título: | Is severity of clinical manifestations following _H. lepturus_ envenomation related to serum TNF-&amp;#x3b1; level?
Autores: | Amir A. Jalali; Mohammad H. Pipelzadeh; Mohammad M. Taraz; Ali A. Khodadadi; Manoochr M. Makvandi.
Data: | 2010-04-25
Ano: | 2010
Palavras-chave: | Immunology.
Resumo: | Thirty six patients, with varying degrees of severity of envenomation, because of envenomation by _Hemiscorpius lepturus_ scorpion, were systematically investigated. The serum levels (by double-ligand ELIZA kit) of interlukin-1 (IL-1), interlukin-6 (IL-6), interlukin-8 (IL-8) and tumor necrosis factor-&amp;#x3b1; (TNF- &amp;#x3b1;) were compared with 30 healthy controls and 10 age-matched patients envenomed by _Mesobuthus eupeus_ scorpion. Blood samples from _M. eupeus_ and _H. lepturus_ victims were taken on admission and once more after 6 hr after serotherapy with multivalent antivenom from _H. lepturus_ envenomed subjects. The results suggest that, unlike _M. eupeus_, the toxic manifestations observed following H lepturus may be associated with increase in serum TNF-&amp;#x3b1; level and are positively correlated with its severity.
Tipo: | Manuscript

Identificador:

http://precedings.nature.com/documents/4382/version/1

oai:nature.com:10101/npre.2010.4382.1

http://hdl.handle.net/10101/npre.2010.4382.1

Fonte: | Nature Precedings
Fonte: | Creative Commons Attribution 3.0 License