Data/hora: 06/06/2024 05:37:41

Provedor de dados: 	17	
País: 	United Kingdom	
Título: 	Reactome - a knowledgebase of human biological pathways	
Autores: 	Bijay Jassal; Esther E. Schmidt; Guanming Wu; Imre Vastrik; David Croft; Bernard de Bono; Gopal Gopinath; Marc Gillespie; Steven Jupe; Gavin O&amp;#x27;Kelly; Lisa Matthews; Phani V. Garapati; Michael Caudy; Alexander Kanapin; Bruce May; Shahana Mahajan; Ewan Birney; Peter  D&amp;#x27;Eustachio; Lincoln Stein.	
Data: 	2009-04-29	
Ano: 	2009	
Palavras-chave: 	Chemistry; Genetics &amp; Genomics; Immunology; Molecular Cell Biology; Bioinformatics.	
Resumo: 	Reactome (&amp;#x22;http://www.reactome.org&amp;#x22;:http://www.reactome.org) is an expert-authored, peer-reviewed knowledgebase of human reactions and pathways that functions as a data mining resource and electronic textbook. Its current release includes 2921 human proteins, 2871 reactions and 4167 literature citations. This curated dataset is integrated with a functional interaction network assembled computationally from non-curated sources of information including protein-protein interactions, gene co-expression, and gene ontology annotations, providing access. A new entity-level pathway viewer and improved search and data mining tools facilitate searching and visualizing pathway data and the analysis of user-supplied high-throughput data sets.&amp;#xd;&amp;#xa; &amp;#xd;&amp;#xa;Reactome has increased its utility to the model organism communities with improved orthology prediction methods allowing pathway inference for 22 species and through collaborations to create manually curated Reactome pathway datasets for species including Arabidopsis, Oryza sativa (rice), Drosophila and Gallus gallus (chicken). Reactome&amp;#x27;s data content and software can all be freely used and redistributed under open source terms. Reactome instances are cross-referenced to corresponding ones in databases including EntrezGene, OMIM, Ensembl, UniProt, the UCSC Genome Browser, KEGG, ChEBI, and Gene Ontology.	
Tipo: 	Poster	
Identificador: 	http://precedings.nature.com/documents/3200/version/1

oai:nature.com:10.1038/npre.2009.3200.1

http://dx.doi.org/10.1038/npre.2009.3200.1	
Fonte: 	Nature Precedings	
Fonte: 	Creative Commons Attribution 3.0 License