Data/hora: 05/06/2024 17:22:49

Provedor de dados: | 17
País: | United Kingdom
Título: | 2011 German Escherichia coli O104:H4 outbreak: Alignment-free whole-genome phylogeny by feature frequency profiles
Autores: | Man Kit Cheung; Lei Li; Wenyan Nong; Hoi Shan Kwan.
Data: | 2011-07-27
Ano: | 2011
Palavras-chave: | Genetics &amp; Genomics; Microbiology; Bioinformatics; Evolutionary Biology.
Resumo: | Accuracy of SNP-based whole-genome phylogeny reconstruction relies heavily on quality of sequence alignment which is particularly hindered by poorly assembled genomes. Alignment-free methods might provide additional insights. Here, we constructed a whole-genome phylogeny of 10 isolates from the current German E. coli outbreak against 30 existing E. coli genomes as well as that of a historical EHEC isolate using the alignment-free feature frequency profile method. Our results revealed a high similarity among E. coli isolates from the current outbreak and the historical EHEC being the most closely related isolate sequenced thus far.
Tipo: | Manuscript

Identificador:

http://precedings.nature.com/documents/6109/version/2

oai:nature.com:10.1038/npre.2011.6109.2

http://dx.doi.org/10.1038/npre.2011.6109.2

Fonte: | Nature Precedings
Fonte: | Creative Commons Attribution 3.0 License