Data/hora: 05/06/2024 15:22:21

Provedor de dados: | 17
País: | United Kingdom
Título: | Open Standards and Resources in Systems Biology: collaborative scale-up toward virtual life
Autores: | Nicolas Le Novere.
Data: | 2006-11-30
Ano: | 2006
Palavras-chave: | Biotechnology; Data Standards.
Resumo: | The practise of Systems Biology relies on interfaces. Interfaces&amp;#xd;&amp;#xa;between the entities we study: the paradigm moved from a physical&amp;#xd;&amp;#xa;object centric view toward a relationship-centric one; interfaces&amp;#xd;&amp;#xa;between tools: From the retrieval of the primary data to the fine&amp;#xd;&amp;#xa;analysis of a model&amp;#x27;s behaviour, one uses many tools, more or less&amp;#xd;&amp;#xa;well connected; interfaces between individuals: To build any&amp;#xd;&amp;#xa;non-trivial mechanistic model requires to merge existing work and&amp;#xd;&amp;#xa;gather external expertise.&amp;#xd;&amp;#xa;&amp;#xd;&amp;#xa;If we want these interfaces to be generic enough to allow for anybody&amp;#xd;&amp;#xa;to leverage on existing toolkits, a fundamental requirement is the&amp;#xd;&amp;#xa;existence of community-developed well supported standards, but also&amp;#xd;&amp;#xa;open resources where to find the &amp;#x22;lego&amp;#x22; blocks. Over the last&amp;#xd;&amp;#xa;half-decade, several efforts have been launched in that direction,&amp;#xd;&amp;#xa;whether concerning encoding format, ontologies or databases. Some of&amp;#xd;&amp;#xa;them are now well-established in the field and play a significant role&amp;#xd;&amp;#xa;to improve its coherence but also to increase the size and the quality&amp;#xd;&amp;#xa;of quantitative models.&amp;#xd;&amp;#xa;
Tipo: | Presentation

Identificador:

http://precedings.nature.com/documents/10/version/1

oai:nature.com:10.1038/npre.2006.10.1

http://dx.doi.org/10.1038/npre.2006.10.1

Fonte: | Nature Precedings
Fonte: | Creative Commons Attribution 3.0 License